Details for: Slc22a1
Associated with
Other Information
Genular Protein ID: 3099228690
Symbol: S22A1_RAT
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7990927
Title: Drug excretion mediated by a new prototype of polyspecific transporter.
PubMed ID: 7990927
DOI: 10.1038/372549a0
PubMed ID: 9195965
Title: Cloning and functional characterization of a rat renal organic cation transporter isoform (rOCT1A).
PubMed ID: 9195965
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8955087
Title: Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.
PubMed ID: 8955087
PubMed ID: 9405386
Title: A reevaluation of substrate specificity of the rat cation transporter rOCT1.
PubMed ID: 9405386
PubMed ID: 9703985
Title: Membrane localization of the electrogenic cation transporter rOCT1 in rat liver.
PubMed ID: 9703985
PubMed ID: 9830022
Title: Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain.
PubMed ID: 9830022
PubMed ID: 9776363
Title: Catecholamine transport by the organic cation transporter type 1 (OCT1).
PubMed ID: 9776363
PubMed ID: 9808712
Title: Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.
PubMed ID: 9808712
PubMed ID: 10570053
Title: Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate.
PubMed ID: 10570053
PubMed ID: 10997918
Title: Localization of organic cation transporters OCT1 and OCT2 in rat kidney.
PubMed ID: 10997918
PubMed ID: 11083459
Title: Differential localization of organic cation transporters rOCT1 and rOCT2 in the basolateral membrane of rat kidney proximal tubules.
PubMed ID: 11083459
PubMed ID: 10864577
Title: The affinity of the organic cation transporter rOCT1 is increased by protein kinase C-dependent phosphorylation.
PubMed ID: 10864577
DOI: 10.1681/asn.v1171216
PubMed ID: 11502595
Title: Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.
PubMed ID: 11502595
PubMed ID: 11408531
Title: Comparison of 'type I' and 'type II' organic cation transport by organic cation transporters and organic anion-transporting polypeptides.
PubMed ID: 11408531
PubMed ID: 11758759
Title: Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.
PubMed ID: 11758759
PubMed ID: 11792693
Title: Tissue distribution and renal developmental changes in rat organic cation transporter mRNA levels.
PubMed ID: 11792693
DOI: 10.1124/dmd.30.2.212
PubMed ID: 12395288
Title: The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP.
PubMed ID: 12395288
PubMed ID: 15122767
Title: Down-regulation of the organic cation transporter 1 of rat liver in obstructive cholestasis.
PubMed ID: 15122767
DOI: 10.1002/hep.20176
PubMed ID: 15817714
Title: Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium.
PubMed ID: 15817714
PubMed ID: 16142924
Title: Purification and functional reconstitution of the rat organic cation transporter OCT1.
PubMed ID: 16142924
DOI: 10.1021/bi050676c
PubMed ID: 15640376
Title: Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney.
PubMed ID: 15640376
PubMed ID: 16272756
Title: Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.
PubMed ID: 16272756
DOI: 10.2133/dmpk.20.379
PubMed ID: 15829703
Title: Individual PKC-phosphorylation sites in organic cation transporter 1 determine substrate selectivity and transport regulation.
PubMed ID: 15829703
PubMed ID: 15662044
Title: Amino acids critical for substrate affinity of rat organic cation transporter 1 line the substrate binding region in a model derived from the tertiary structure of lactose permease.
PubMed ID: 15662044
PubMed ID: 16581093
Title: Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain.
PubMed ID: 16581093
PubMed ID: 17567940
Title: Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity.
PubMed ID: 17567940
PubMed ID: 17553914
Title: Effect of pregnane X receptor ligand on pharmacokinetics of substrates of organic cation transporter Oct1 in rats.
PubMed ID: 17553914
PubMed ID: 17616214
Title: Transport of organic cations across the blood-testis barrier.
PubMed ID: 17616214
DOI: 10.1021/mp070023l
PubMed ID: 22673903
Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
PubMed ID: 22673903
DOI: 10.1038/ncomms1871
Sequence Information:
- Length: 556
- Mass: 61541
- Checksum: 9F42131CCCEC0920
- Sequence:
MPTVDDVLEQ VGEFGWFQKQ AFLLLCLISA SLAPIYVGIV FLGFTPGHYC QNPGVAELSQ RCGWSQAEEL NYTVPGLGPS DEASFLSQCM RYEVDWNQST LDCVDPLSSL VANRSQLPLG PCEHGWVYDT PGSSIVTEFN LVCGDAWKVD LFQSCVNLGF FLGSLVVGYI ADRFGRKLCL LVTTLVTSVS GVLTAVAPDY TSMLLFRLLQ GMVSKGSWVS GYTLITEFVG SGYRRTTAIL YQMAFTVGLV GLAGVAYAIP DWRWLQLAVS LPTFLFLLYY WFVPESPRWL LSQKRTTRAV RIMEQIAQKN GKVPPADLKM LCLEEDASEK RSPSFADLFR TPNLRKHTVI LMYLWFSCAV LYQGLIMHVG ATGANLYLDF FYSSLVEFPA AFIILVTIDR IGRIYPIAAS NLVTGAACLL MIFIPHELHW LNVTLACLGR MGATIVLQMV CLVNAELYPT FIRNLGMMVC SALCDLGGIF TPFMVFRLME VWQALPLILF GVLGLTAGAM TLLLPETKGV ALPETIEEAE NLGRRKSKAK ENTIYLQVQT GKSSST
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.