Genular: Defining Cellular Identity and Function

Details for: Cd8a

Gene ID: 24930

Symbol: Cd8a

Ensembl ID: ENSRNOG00000007178

Description: CD8 subunit alpha

Associated with

Adaptive immune system
(R-RNO-1280218)
Immune system
(R-RNO-168256)
Immunoregulatory interactions between a lymphoid and a non-lymphoid cell
(R-RNO-198933)
Calcium-mediated signaling
(GO:0019722)
Cell surface
(GO:0009986)
Cell surface receptor signaling pathway
(GO:0007166)
Cytotoxic t cell differentiation
(GO:0045065)
Defense response to virus
(GO:0051607)
External side of plasma membrane
(GO:0009897)
Identical protein binding
(GO:0042802)
Mhc class i protein complex binding
(GO:0023024)
Plasma membrane
(GO:0005886)
Plasma membrane raft
(GO:0044853)
Positive regulation of calcium-mediated signaling
(GO:0050850)
Protein kinase binding
(GO:0019901)
Receptor complex
(GO:0043235)
T cell activation
(GO:0042110)
T cell mediated immunity
(GO:0002456)
T cell receptor signaling pathway
(GO:0050852)

Other Information

Proteins

T-cell surface glycoprotein CD8 alpha chain

Genular Protein ID: 1806122924

Symbol: CD8A_RAT

Name: T-cell surface glycoprotein CD8 alpha chain

UniProtKB Accession Codes:

P07725

Database IDs:

Citations:

PubMed ID: 3932064

Title: Purification, chain separation and sequence of the MRC OX-8 antigen, a marker of rat cytotoxic T lymphocytes.

PubMed ID: 3932064

DOI: 10.1002/j.1460-2075.1985.tb03968.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1908233

Title: Glycosylation sites identified by detection of glycosylated amino acids released from Edman degradation: the identification of Xaa-Pro-Xaa-Xaa as a motif for Thr-O-glycosylation.

PubMed ID: 1908233

DOI: 10.1016/0006-291x(91)91019-9

Sequence Information:

Length: 236
Mass: 26196
Checksum: ADFAC54E4C99C1BE
Sequence:

MASRVICFLS LNLLLLDVIT RLQVSGQLQL SPKKVDAEIG QEVKLTCEVL RDTSQGCSWL 
FRNSSSELLQ PTFIIYVSSS RSKLNDILDP NLFSARKENN KYILTLSKFS TKNQGYYFCS 
ITSNSVMYFS PLVPVFQKVN SIITKPVTRA PTPVPPPTGT PRPLRPEACR PGASGSVEGM 
GLGFACDIYI WAPLAGICAV LLLSLVITLI CCHRNRRRVC KCPRPLVKPR PSEKFV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.