Genular: Defining Cellular Identity and Function

Details for: RT1 Db2

Gene ID: 24981

Symbol: RT1 Db2

Ensembl ID: ENSRNOG00000030431

Description: RT1 class II, locus Db2

Associated with

Adaptive immune system
(R-RNO-1280218)
Costimulation by the cd28 family
(R-RNO-388841)
Downstream tcr signaling
(R-RNO-202424)
Generation of second messenger molecules
(R-RNO-202433)
Immune system
(R-RNO-168256)
Mhc class ii antigen presentation
(R-RNO-2132295)
Pd-1 signaling
(R-RNO-389948)
Phosphorylation of cd3 and tcr zeta chains
(R-RNO-202427)
Tcr signaling
(R-RNO-202403)
Translocation of zap-70 to immunological synapse
(R-RNO-202430)
Adaptive immune response
(GO:0002250)
Antigen processing and presentation of exogenous peptide antigen via mhc class ii
(GO:0019886)
Late endosome membrane
(GO:0031902)
Lysosomal membrane
(GO:0005765)
Mhc class ii protein complex
(GO:0042613)
Mhc class ii protein complex binding
(GO:0023026)
Peptide antigen assembly with mhc class ii protein complex
(GO:0002503)
Peptide antigen binding
(GO:0042605)
Positive regulation of immune response
(GO:0050778)
Positive regulation of t cell activation
(GO:0050870)

Other Information

Proteins

A0A023IKK2_RAT

Genular Protein ID: 1840972802

Symbol: A0A023IKK2_RAT

Name: N/A

UniProtKB Accession Codes:

A0A023IKK2 A0A0G2JZX8 D3ZT06

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

PubMed ID: 24586191

Title: Natural polymorphisms in Tap2 influence negative selection and CD4?CD8 lineage commitment in the rat.

PubMed ID: 24586191

DOI: 10.1371/journal.pgen.1004151

Sequence Information:

Length: 287
Mass: 32180
Checksum: 44DC8F3C5A80DA9C
Sequence:

MVCLWLPRDP CVAAVVLSLL MLSPPVALVR DPRPRFLEQL KAECHYVKGR EHVWSVTRFI 
YNQEEFARFD SVFGKFLAVT ELGRPIAEYL NTQKDMLDNY RASVDRCRNN YDLVDIFMSN 
LKAKPKVTVY PSKTQPLEYH NLLVCSVSDF YPGTIEIRWF RNGEEEKTGV VSTDLISNGD 
WTYQTLVMLE TVPQGGEVYT CQVEHPSLTS PVRVEWRARS TSAQNKMLSG AMGMALGLFI 
LAVGLFIYLR NLRAGSVSHG AGEGAESSTS RLTGSRSECH TGPALSV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.