Details for: ALPP

Gene ID: 250

Symbol: ALPP

Ensembl ID: ENSG00000163283

Description: alkaline phosphatase, placental

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 31.2249
    Cell Significance Index: -7.9200
  • Cell Name: trophoblast giant cell (CL0002488)
    Fold Change: 23.9503
    Cell Significance Index: 172.5500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3053
    Cell Significance Index: 166.7300
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 0.0375
    Cell Significance Index: 1.6300
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.0079
    Cell Significance Index: 0.1100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0011
    Cell Significance Index: 0.1300
  • Cell Name: lung pericyte (CL0009089)
    Fold Change: 0.0003
    Cell Significance Index: 0.0000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0008
    Cell Significance Index: -0.4400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0010
    Cell Significance Index: -0.0400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0012
    Cell Significance Index: -0.9200
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.0025
    Cell Significance Index: -0.0300
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: -0.0027
    Cell Significance Index: -0.0300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0045
    Cell Significance Index: -2.8500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0046
    Cell Significance Index: -0.9800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0052
    Cell Significance Index: -3.9400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0056
    Cell Significance Index: -0.1500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0060
    Cell Significance Index: -1.0200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0087
    Cell Significance Index: -3.9700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0136
    Cell Significance Index: -2.4500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0167
    Cell Significance Index: -0.7800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0192
    Cell Significance Index: -2.7900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0207
    Cell Significance Index: -4.1600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0228
    Cell Significance Index: -4.5300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0238
    Cell Significance Index: -2.9300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0268
    Cell Significance Index: -3.6800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0444
    Cell Significance Index: -0.9300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0508
    Cell Significance Index: -3.2000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0592
    Cell Significance Index: -6.7800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.0608
    Cell Significance Index: -0.9400
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: -0.0630
    Cell Significance Index: -0.8000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0703
    Cell Significance Index: -4.7300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.0855
    Cell Significance Index: -0.9300
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.1008
    Cell Significance Index: -2.0100
  • Cell Name: PP cell (CL0000696)
    Fold Change: -0.1011
    Cell Significance Index: -1.0300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1024
    Cell Significance Index: -3.7600
  • Cell Name: IgA plasma cell (CL0000987)
    Fold Change: -0.1156
    Cell Significance Index: -0.7700
  • Cell Name: peridermal cell (CL0000078)
    Fold Change: -0.1219
    Cell Significance Index: -0.7600
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1294
    Cell Significance Index: -2.9900
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1325
    Cell Significance Index: -2.2500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1393
    Cell Significance Index: -4.5600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1487
    Cell Significance Index: -4.7400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1508
    Cell Significance Index: -4.0400
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1576
    Cell Significance Index: -3.9300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1656
    Cell Significance Index: -4.7300
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.1660
    Cell Significance Index: -1.9100
  • Cell Name: articular chondrocyte (CL1001607)
    Fold Change: -0.1716
    Cell Significance Index: -0.9300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1719
    Cell Significance Index: -4.5200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1739
    Cell Significance Index: -2.4900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1769
    Cell Significance Index: -4.5200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1836
    Cell Significance Index: -4.5800
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.1890
    Cell Significance Index: -1.4600
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.1916
    Cell Significance Index: -1.8200
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1938
    Cell Significance Index: -4.8400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1979
    Cell Significance Index: -4.2000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.1991
    Cell Significance Index: -3.6800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2037
    Cell Significance Index: -4.4600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2037
    Cell Significance Index: -4.4000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2118
    Cell Significance Index: -6.0700
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.2140
    Cell Significance Index: -3.1300
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.2151
    Cell Significance Index: -4.4900
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.2181
    Cell Significance Index: -2.7600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2187
    Cell Significance Index: -4.3900
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.2294
    Cell Significance Index: -4.4900
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.2303
    Cell Significance Index: -2.3800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2377
    Cell Significance Index: -4.7000
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.2388
    Cell Significance Index: -4.7000
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.2392
    Cell Significance Index: -2.9100
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.2432
    Cell Significance Index: -4.0900
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.2432
    Cell Significance Index: -2.8600
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.2449
    Cell Significance Index: -2.9200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2528
    Cell Significance Index: -4.2300
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.2538
    Cell Significance Index: -4.1100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2585
    Cell Significance Index: -2.3800
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.2627
    Cell Significance Index: -4.4900
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.2662
    Cell Significance Index: -1.9100
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.2698
    Cell Significance Index: -3.4100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.2707
    Cell Significance Index: -4.6800
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: -0.2715
    Cell Significance Index: -1.6800
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.2829
    Cell Significance Index: -3.9700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2837
    Cell Significance Index: -7.5900
  • Cell Name: myoepithelial cell (CL0000185)
    Fold Change: -0.2847
    Cell Significance Index: -3.2300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2922
    Cell Significance Index: -3.0300
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: -0.3026
    Cell Significance Index: -3.2300
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.3088
    Cell Significance Index: -4.0300
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.3106
    Cell Significance Index: -4.2300
  • Cell Name: pulmonary alveolar type 1 cell (CL0002062)
    Fold Change: -0.3179
    Cell Significance Index: -3.4900
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.3194
    Cell Significance Index: -4.0000
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: -0.3211
    Cell Significance Index: -2.9800
  • Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
    Fold Change: -0.3218
    Cell Significance Index: -3.2200
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.3222
    Cell Significance Index: -4.5200
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: -0.3235
    Cell Significance Index: -3.8500
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: -0.3280
    Cell Significance Index: -3.2200
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.3296
    Cell Significance Index: -4.3800
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: -0.3309
    Cell Significance Index: -3.3800
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.3322
    Cell Significance Index: -4.1500
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.3324
    Cell Significance Index: -4.2000
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.3383
    Cell Significance Index: -4.7300
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.3399
    Cell Significance Index: -3.7800
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.3413
    Cell Significance Index: -4.0300
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.3452
    Cell Significance Index: -3.8900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression Pattern:** ALPP is expressed in a diverse range of cell types, including oligodendrocyte precursor cells, progenitor cells, endothelial cells, pericytes, goblet cells, cardiac endothelial cells, and neoplastic cells. 2. **Enzymatic Activity:** ALPP exhibits alkaline phosphatase activity, which involves the removal of phosphate groups from various substrates, including phospholipids, proteins, and nucleotides. 3. **Cell Surface Expression:** ALPP is localized to the cell surface, where it can interact with other proteins and lipids to regulate cellular signaling and trafficking. 4. **Zinc and Magnesium Binding:** ALPP binds to zinc and magnesium ions, which are essential cofactors for its enzymatic activity. **Pathways and Functions:** 1. **Dephosphorylation:** ALPP plays a crucial role in dephosphorylation reactions, including the removal of phosphate groups from phospholipids, proteins, and nucleotides. 2. **Intra-Golgi and Retrograde Golgi-to-Er Trafficking:** ALPP is involved in the regulation of intra-golgi and retrograde golgi-to-er trafficking, which is essential for the proper functioning of cellular membranes and protein secretion. 3. **Membrane Trafficking:** ALPP regulates membrane trafficking by interacting with other proteins and lipids to modulate the dynamics of cellular membrane structure and function. 4. **Protein Binding:** ALPP binds to various proteins, including proteins involved in signaling pathways, protein degradation, and protein transport. **Clinical Significance:** 1. **Cancer Metastasis:** ALPP has been implicated in the regulation of metastasis in various cancers, including breast, lung, and colon cancer. 2. **Neurological Disorders:** ALPP has been linked to neurological disorders, such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. 3. **Cardiovascular Disease:** ALPP has been found to play a role in cardiovascular disease, including atherosclerosis and cardiac remodeling. 4. **Immunological Disorders:** ALPP has been implicated in immunological disorders, including autoimmune diseases and inflammatory responses. In conclusion, ALPP is a multifunctional enzyme that plays a crucial role in various cellular processes, including dephosphorylation, membrane trafficking, and protein binding. Its expression pattern and involvement in multiple pathways underscore its significance in various biological processes, including cancer metastasis, neurological disorders, cardiovascular disease, and immunological responses. Further research is needed to fully elucidate the biological functions and clinical implications of ALPP.

Genular Protein ID: 3168680542

Symbol: PPB1_HUMAN

Name: Alkaline phosphatase, placental type

UniProtKB Accession Codes:

P05187 P05188 P06861 Q53S78 Q96DB7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 21 ChEMBL 1 ChiTaRS 1 DEPOD 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EC 2 EMBL 9 Ensembl 1 EvolutionaryTrace 1 GO 6 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 2 SABIO-RK 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3042787

Title: Nucleotide sequence of the human placental alkaline phosphatase gene. Evolution of the 5' flanking region by deletion/substitution.

PubMed ID: 3042787

DOI: 10.1016/s0021-9258(18)37887-6

PubMed ID: 3512548

Title: Molecular cloning and sequence analysis of human placental alkaline phosphatase.

PubMed ID: 3512548

DOI: 10.1016/s0021-9258(17)35755-1

PubMed ID: 3461452

Title: Products of two common alleles at the locus for human placental alkaline phosphatase differ by seven amino acids.

PubMed ID: 3461452

DOI: 10.1073/pnas.83.15.5597

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3001717

Title: Cloning, sequencing, and chromosomal localization of human term placental alkaline phosphatase cDNA.

PubMed ID: 3001717

DOI: 10.1073/pnas.82.24.8715

PubMed ID: 6651840

Title: Purification and partial sequencing of human placental alkaline phosphatase.

PubMed ID: 6651840

DOI: 10.1016/s0006-291x(83)80252-6

PubMed ID: 3459156

Title: Expression of different-sized placental alkaline phosphatase mRNAs in placenta and choriocarcinoma cells.

PubMed ID: 3459156

DOI: 10.1073/pnas.83.11.3781

PubMed ID: 3422741

Title: Aspartic acid-484 of nascent placental alkaline phosphatase condenses with a phosphatidylinositol glycan to become the carboxyl terminus of the mature enzyme.

PubMed ID: 3422741

DOI: 10.1073/pnas.85.5.1398

PubMed ID: 2153284

Title: Selectivity of the cleavage/attachment site of phosphatidylinositol-glycan-anchored membrane proteins determined by site-specific mutagenesis at Asp-484 of placental alkaline phosphatase.

PubMed ID: 2153284

DOI: 10.1073/pnas.87.1.157

PubMed ID: 1939159

Title: Mutation of a single amino acid converts germ cell alkaline phosphatase to placental alkaline phosphatase.

PubMed ID: 1939159

DOI: 10.1016/s0021-9258(18)54836-5

PubMed ID: 1730777

Title: Site-specific mutations in the COOH-terminus of placental alkaline phosphatase: a single amino acid change converts a phosphatidylinositol-glycan-anchored protein to a secreted protein.

PubMed ID: 1730777

DOI: 10.1083/jcb.116.3.799

PubMed ID: 11937510

Title: Function assignment to conserved residues in mammalian alkaline phosphatases.

PubMed ID: 11937510

DOI: 10.1074/jbc.m202298200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 25775211

Title: Functional significance of calcium binding to tissue-nonspecific alkaline phosphatase.

PubMed ID: 25775211

DOI: 10.1371/journal.pone.0119874

PubMed ID: 11124260

Title: Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution. Implication for a substrate specificity.

PubMed ID: 11124260

DOI: 10.1074/jbc.m009250200

PubMed ID: 15946677

Title: Structural studies of human placental alkaline phosphatase in complex with functional ligands.

PubMed ID: 15946677

DOI: 10.1016/j.jmb.2005.04.068

PubMed ID: 16815919

Title: Structural studies of human alkaline phosphatase in complex with strontium: implication for its secondary effect in bones.

PubMed ID: 16815919

DOI: 10.1110/ps.062123806

PubMed ID: 20693656

Title: Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site.

PubMed ID: 20693656

DOI: 10.1107/s1744309110019767

Sequence Information:

  • Length: 535
  • Mass: 57954
  • Checksum: 13C136679A70C76B
  • Sequence:
    • MLGPCMLLLL LLLGLRLQLS LGIIPVEEEN PDFWNREAAE ALGAAKKLQP AQTAAKNLII 
FLGDGMGVST VTAARILKGQ KKDKLGPEIP LAMDRFPYVA LSKTYNVDKH VPDSGATATA 
YLCGVKGNFQ TIGLSAAARF NQCNTTRGNE VISVMNRAKK AGKSVGVVTT TRVQHASPAG 
TYAHTVNRNW YSDADVPASA RQEGCQDIAT QLISNMDIDV ILGGGRKYMF RMGTPDPEYP 
DDYSQGGTRL DGKNLVQEWL AKRQGARYVW NRTELMQASL DPSVTHLMGL FEPGDMKYEI 
HRDSTLDPSL MEMTEAALRL LSRNPRGFFL FVEGGRIDHG HHESRAYRAL TETIMFDDAI 
ERAGQLTSEE DTLSLVTADH SHVFSFGGYP LRGSSIFGLA PGKARDRKAY TVLLYGNGPG 
YVLKDGARPD VTESESGSPE YRQQSAVPLD EETHAGEDVA VFARGPQAHL VHGVQEQTFI 
AHVMAFAACL EPYTACDLAP PAGTTDAAHP GRSVVPALLP LLAGTLLLLE TATAP

Genular Protein ID: 195624628

Symbol: B2R7C7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2R7C7

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 16 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 4 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 1 RuleBase 2 SAM 2 SMART 1 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 535
  • Mass: 57854
  • Checksum: EEB12EED89A2C6A4
  • Sequence:
    • MLGPCMLLLL LLLGLRLQLS LGIIPVEEEN PDFWNRQAAE ALGAAKKLQP AQTAAKNLII 
FLGDGMGVST VTAARILKGQ KKDKLGPEIP LAMDRFPYVA LSKTYNVDKH VPDSGATATA 
YLCGVKGNFQ TIGLSAAARF NQCNTTRGNE VISVMNRAKK AGKSVGVVTT TRVQHASPAG 
TYAHTVNRNW YSDADVPASA RQEGCQDIAT QLISNMDIDV ILGGGRKYMF RMGTPDPEYP 
DDYSQGGTRL DGKNLVQEWL AKRQGARYVW NRTELMQASL DPSVTHLMGL FEPGDMKYEI 
HRDSTLDPSL MEMTEAALRL LSRNPRGFFL FVEGGRIDHG HHESRAYGAL TETIMFDDAI 
ERAGQLTSEE DTLSLVTADH SHVFSFGGYP LRGSSIFGLA PGKARDRKAY TVLLYGNGPG 
YVLKDGARPD VTESESGSPE YRQQSAVPLD EETHAGEDVA VFARGPQAHL VHGVQEQTFI 
AHVMAFAACL EPYTACDLAP PAGTTDAAHP GRSVVPALLP LLAGTLLLLE TATAP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.