Details for: Cyp2c12

Gene ID: 25011

Symbol: Cyp2c12

Ensembl ID: ENSRNOG00000047945

Description: cytochrome P450, family 2, subfamily c, polypeptide 12

Associated with

  • Arachidonic acid epoxygenase activity
    (GO:0008392)
  • Aromatase activity
    (GO:0070330)
  • Cytoplasm
    (GO:0005737)
  • Endoplasmic reticulum
    (GO:0005783)
  • Endoplasmic reticulum membrane
    (GO:0005789)
  • Epoxygenase p450 pathway
    (GO:0019373)
  • Heme binding
    (GO:0020037)
  • Intracellular membrane-bounded organelle
    (GO:0043231)
  • Iron ion binding
    (GO:0005506)
  • Monooxygenase activity
    (GO:0004497)
  • Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    (GO:0016705)
  • Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    (GO:0016712)
  • Xenobiotic metabolic process
    (GO:0006805)

Other Information

Genular Protein ID: 1506419382

Symbol: CP2CC_RAT

Name: Cytochrome P450 2C12, female-specific

UniProtKB Accession Codes:

P11510

Database IDs:

AGR 1 AlphaFoldDB 1 CDD 1 CTD 1 ChEBI 10 DrugBank 1 EC 2 EMBL 1 GO 10 Gene3D 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 RGD 1 RefSeq 1 Rhea 3 SMR 1 STRING 1 SUPFAM 1 eggNOG 1

Citations:

PubMed ID: 2837761

Title: cDNA cloning, sequence, and regulation of a major female-specific and growth hormone-inducible rat liver cytochrome P-450 active in 15 beta-hydroxylation of steroid sulfates.

PubMed ID: 2837761

DOI: 10.1073/pnas.85.12.4214

PubMed ID: 3164963

Title: Sequence and regulation of two growth-hormone-controlled, sex-specific isozymes of cytochrome P-450 in rat liver, P-450(15)beta and P-450(16)alpha.

PubMed ID: 3164963

Sequence Information:

  • Length: 490
  • Mass: 55919
  • Checksum: C2B637DA69F62C82
  • Sequence:
    • MDPFVVLVLS LSFLLLLYLW RPSPGRGKLP PGPTPLPIFG NFLQIDMKDI RQSISNFSKT 
YGPVFTLYFG SQPTVVLHGY EAVKEALIDY GEEFSGRGRM PVFEKATKGL GISFSRGNVW 
RATRHFTVNT LRSLGMGKRT IEIKVQEEAE WLVMELKKTK GSPCDPKFII GCAPCNVICS 
IIFQNRFDYK DKDFLSLIEN VNEYIKIVST PAFQVFNAFP ILLDYCPGNH KTHSKHFAAI 
KSYLLKKIKE HEESLDVSNP RDFIDYFLIQ RCQENGNQQM NYTQEHLAIL VTNLFIGGTE 
TSSLTLRFAL LLLMKYPHIT DKVQEEIGQV IGRHRSPCML DRIHMPYTNA MIHEVQRYID 
LAPNGLLHEV TCDTKFRDYF IPKGTAVLTS LTSVLHARKE FPNPEMFDPG HFLDENGNFK 
KSDYFMPFSA GKRKCVGEGL ASMELFLFLT TILQNFKLKS LSDPKDIDIN SIRSEFSSIP 
PTFQLCFIPV

Genular Protein ID: 665142067

Symbol: A0A9K3Y6X0_RAT

Name: N/A

UniProtKB Accession Codes:

A0A9K3Y6X0

Database IDs:

ARBA 8 CDD 1 CTD 1 EMBL 10 GO 4 Gene3D 1 HOGENOM 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 1 Pfam 1 Proteomes 1 RGD 2 RefSeq 1 RuleBase 1 SAM 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

  • Length: 490
  • Mass: 55894
  • Checksum: AF77EA6A18E27897
  • Sequence:
    • MDPFVVLVLS LSFLLLLYLW RPSPGRGKLP PGPTPLPIFG NFLQIDMKDI RQSISNFSKT 
YGPVFTLYFG SQPTVVLHGY EAVKEALIDY GEEFSGRGRM PVFEKATKGL GISFSRGNVW 
RATRHFTVNT LRSLGMGKRT IEIKVQEEAE WLVMELKKTK GSPCDPKFII GCAPCNVICS 
IIFQNRFDYK DKDFLSLIEN VNEYIKIVST PAFQVFNAFP ILLDYCPGNH KTHSKHFAAI 
KSYLLKKIKE HEESLDVSNP RDFIDYFLIQ RCQENGNQQM NYTQEHLAIL VTNLFIGGTE 
TSSLTLRFAL LLLMKYPHIT DKVQEEIGQV IGRHRSPCML DRIHMPYTNA MIHEVQRYID 
LAPNGLLHEV TCDTKFRDYF IPKGTAVLTS LTSVLHDSKE FPNPEMFDPG HFLDENGNFK 
KSDYFMPFSA GKRKCVGEGL ASMELFLFLT TILQNFKLKS LSDPKDIDIN SIRSEFSSIP 
PTFQLCFIPV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.