Genular: Defining Cellular Identity and Function

Details for: Itgam

Gene ID: 25021

Symbol: Itgam

Ensembl ID: ENSRNOG00000019728

Description: integrin subunit alpha M

Associated with

Extracellular matrix organization
(R-RNO-1474244)
Integrin cell surface interactions
(R-RNO-216083)
Activated t cell proliferation
(GO:0050798)
Amyloid-beta clearance
(GO:0097242)
Cargo receptor activity
(GO:0038024)
Cell-cell adhesion
(GO:0098609)
Cell adhesion
(GO:0007155)
Cell surface
(GO:0009986)
Cellular extravasation
(GO:0045123)
Complement-mediated synapse pruning
(GO:0150062)
Complement component c3b binding
(GO:0001851)
Complement receptor mediated signaling pathway
(GO:0002430)
Ectodermal cell differentiation
(GO:0010668)
External side of plasma membrane
(GO:0009897)
Extracellular space
(GO:0005615)
Forebrain development
(GO:0030900)
Heat shock protein binding
(GO:0031072)
Heparan sulfate proteoglycan binding
(GO:0043395)
Heparin binding
(GO:0008201)
Heterotypic cell-cell adhesion
(GO:0034113)
Integrin-mediated signaling pathway
(GO:0007229)
Integrin alpham-beta2 complex
(GO:0034688)
Leukocyte adhesion to vascular endothelial cell
(GO:0061756)
Leukocyte cell-cell adhesion
(GO:0007159)
Leukocyte migration involved in inflammatory response
(GO:0002523)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Microglia development
(GO:0014005)
Microglial cell activation
(GO:0001774)
Negative regulation of dopamine metabolic process
(GO:0045963)
Neutrophil apoptotic process
(GO:0001781)
Neutrophil chemotaxis
(GO:0030593)
Nucleus
(GO:0005634)
Opsonin binding
(GO:0001846)
Phagocytosis
(GO:0006909)
Phagocytosis, engulfment
(GO:0006911)
Plasma membrane
(GO:0005886)
Plasma membrane raft
(GO:0044853)
Positive regulation of mast cell differentiation
(GO:0060376)
Positive regulation of microglial cell mediated cytotoxicity
(GO:1904151)
Positive regulation of neutrophil degranulation
(GO:0043315)
Positive regulation of protein targeting to membrane
(GO:0090314)
Positive regulation of superoxide anion generation
(GO:0032930)
Protein-containing complex binding
(GO:0044877)
Receptor-mediated endocytosis
(GO:0006898)
Response to curcumin
(GO:1904643)
Response to estradiol
(GO:0032355)
Response to gram-positive bacterium
(GO:0140459)
Response to ischemia
(GO:0002931)
Response to mechanical stimulus
(GO:0009612)
Vertebrate eye-specific patterning
(GO:0150064)

Other Information

Proteins

Q9JI30_RAT

Genular Protein ID: 3356621311

Symbol: Q9JI30_RAT

Name: N/A

UniProtKB Accession Codes:

Q9JI30

Database IDs:

Citations:

PubMed ID: 15072240

Title: Cloning of the rat CR3 alphaM (CD11b) subunit, expression and binding assay of recombinant isolated CD11b VA (A-domain) and ICAM-1 Ig modules.

PubMed ID: 15072240

Sequence Information:

Length: 1151
Mass: 126944
Checksum: 8F785695D4074CA5
Sequence:

MTLKVLLATV LTLCHGFNLD TENPMTFQEN ASGFGQSVIQ LGETRVVVAA PQEVKAVNQT 
GALYQCDYST NRCDPIPLQV PPEAVNMSLG LSLAATTVPP QLLACGPTVH QNCKENTYVN 
GLCYLFGSNL LRKPQQFPEA LRGCPQQESN IAFLIDGSGS INTIDFQKMK EFVSTVMDQF 
QKSKTLFSLM QYSDEFRTHF TFNDFKRNPD PKSHVRPIRQ LNGRTKTASG IRKVVRELFQ 
KINGARDNAA KILVVITDGE KFGDPLNYED VIPEAEEAGI IRYVIGVGNA FHKPQSRREL 
DTIASKPAGD HVFQVDNFEA LNTIRNQLQE KIFAIEGTQT GSTSSFEHEM SQEGFSAAIT 
SNGPLLGSVG SFDWAGGAFL YPSKDKASFI NTTRIDSDMN DAYLGYASAV ISRNRVQSLV 
LGAPRYQHIG LVVMFKQNFG AWEPHTDIKG SQIGSYFGAS LCSVDMDADG NTNLILIGAP 
HHYEKTRGGQ VSVCPLPRGR ARWQCEAILH GDQGHPWGRF GAALTVLGDV NGDKLTDVAI 
GAPGEQENQG AVYIFHGASV ASISTPHSQR IAGARFSPGL QYFGQSLSGG KDLTMDGLMD 
LAVGAQGRLL LIRAQPVLRL EATMEFSPKN LARSVFACQE EVVKNKDAGE VRVCLQVRKN 
TKDRLREGDI QSTVTYDLAL DPGRSVVRAF FDETKNGILR RIRVFGLTQK CETLKLILPD 
CVDNSVSPII LRLNYTLVGE PLRSSRDLRP VLAMEAQRIF TAMFPFEKNC GNDTICQDDL 
SITVSSTRVN TLVVGDSRDF DVSVTLRNDG EDSYGTKVTC YYPSGLSYRK VSASQNQFSK 
KPWRVIAEPS SSEGQGVLKS TIWDINHPIF PANSEVTFNV TFDVDSDASL GNKLLLKVVV 
TSENNVSRTD KTESQLELPV KYAIYMVVTS GESSIKYLNF TASEMTSKVI QHQYQFNNLG 
QRSFPVSVVF WIPVQINKVT IWDPPQVTFS QNLSSVCRTE QKSPSHSKFQ DELERTPVLN 
CSVAVCKRIQ CDIPSFNSKE IFNVTLQGNL LFDWYIETSH DHLLLVSTAE ILFNDSAFAL 
LPGQETFVKA QTETKVEPYT VHNPVPLIVG SSVGGLVLLA LITAGLYKLG FFKRQYKDMM 
NEAGGQDGPP Q

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Itgam

Associated with

Other Information

Cloning of the rat CR3 alphaM (CD11b) subunit, expression and binding assay of recombinant isolated CD11b VA (A-domain) and ICAM-1 Ig modules. PubMed ID: 15072240

Database document:

PubMed ID: 15072240