Details for: Camk4

Gene ID: 25050

Symbol: Camk4

Ensembl ID: ENSRNOG00000020478

Description: calcium/calmodulin-dependent protein kinase IV

Associated with

Other Information

Genular Protein ID: 2182656101

Symbol: KCC4_RAT

Name: Calcium/calmodulin-dependent protein kinase type IV

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1648230

Title: Relationship of genes encoding Ca2+/calmodulin-dependent protein kinase Gr and calspermin: a gene within a gene.

PubMed ID: 1648230

DOI: 10.1073/pnas.88.13.5784

PubMed ID: 1649385

Title: A novel Ca2+/calmodulin-dependent protein kinase and a male germ cell-specific calmodulin-binding protein are derived from the same gene.

PubMed ID: 1649385

DOI: 10.1128/mcb.11.8.3960-3971.1991

PubMed ID: 8412563

Title: Cloning and sequencing of a gene encoding the beta polypeptide of Ca2+/calmodulin-dependent protein kinase IV and its expression confined to the mature cerebellar granule cells.

PubMed ID: 8412563

DOI: 10.1016/0169-328x(93)90029-o

PubMed ID: 7493991

Title: Organization and analysis of the complete rat calmodulin-dependent protein kinase IV gene.

PubMed ID: 7493991

DOI: 10.1074/jbc.270.49.29507

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2538431

Title: Ca2+/calmodulin-dependent protein kinase enriched in cerebellar granule cells. Identification of a novel neuronal calmodulin-dependent protein kinase.

PubMed ID: 2538431

DOI: 10.1016/s0021-9258(18)83630-4

PubMed ID: 2914893

Title: Molecular cloning sequence and distribution of rat calspermin, a high affinity calmodulin-binding protein.

PubMed ID: 2914893

DOI: 10.1016/s0021-9258(18)94144-x

PubMed ID: 1646483

Title: CREB: a Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases.

PubMed ID: 1646483

DOI: 10.1126/science.1646483

PubMed ID: 7961813

Title: Activation mechanisms for Ca2+/calmodulin-dependent protein kinase IV. Identification of a brain CaM-kinase IV kinase.

PubMed ID: 7961813

DOI: 10.1016/s0021-9258(19)61953-8

PubMed ID: 8065343

Title: Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.

PubMed ID: 8065343

DOI: 10.1128/mcb.14.9.6107-6116.1994

PubMed ID: 7592527

Title: Full activation of brain calmodulin-dependent protein kinase IV requires phosphorylation of the amino-terminal serine-rich region by calmodulin-dependent protein kinase IV kinase.

PubMed ID: 7592527

DOI: 10.1093/oxfordjournals.jbchem.a124764

PubMed ID: 7615569

Title: Phosphorylation and activation of Ca(2+)-calmodulin-dependent protein kinase IV by Ca(2+)-calmodulin-dependent protein kinase Ia kinase. Phosphorylation of threonine 196 is essential for activation.

PubMed ID: 7615569

DOI: 10.1074/jbc.270.29.17616

PubMed ID: 8621702

Title: Regulation of activating transcription factor-1 and the cAMP response element-binding protein by Ca2+/calmodulin-dependent protein kinases type I, II, and IV.

PubMed ID: 8621702

DOI: 10.1074/jbc.271.6.3066

PubMed ID: 8636117

Title: Inactivation of calmodulin-dependent protein kinase IV by autophosphorylation of serine 332 within the putative calmodulin-binding domain.

PubMed ID: 8636117

DOI: 10.1074/jbc.271.12.6903

PubMed ID: 8631893

Title: Multiple Ca(2+)-calmodulin-dependent protein kinase kinases from rat brain. Purification, regulation by Ca(2+)-calmodulin, and partial amino acid sequence.

PubMed ID: 8631893

DOI: 10.1074/jbc.271.18.10806

PubMed ID: 9822657

Title: Components of a calmodulin-dependent protein kinase cascade. Molecular cloning, functional characterization and cellular localization of Ca2+/calmodulin-dependent protein kinase kinase beta.

PubMed ID: 9822657

DOI: 10.1074/jbc.273.48.31880

PubMed ID: 9596578

Title: A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A.

PubMed ID: 9596578

DOI: 10.1126/science.280.5367.1258

PubMed ID: 10336483

Title: Substrate recognition by Ca2+/Calmodulin-dependent protein kinase kinase. Role of the arg-pro-rich insert domain.

PubMed ID: 10336483

DOI: 10.1074/jbc.274.22.15803

PubMed ID: 14701808

Title: Catalytic activity is required for calcium/calmodulin-dependent protein kinase IV to enter the nucleus.

PubMed ID: 14701808

DOI: 10.1074/jbc.m312613200

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

  • Length: 474
  • Mass: 53151
  • Checksum: E7B20E942419EB89
  • Sequence:
  • MLKVTVPSCP SSPCSSVTSS TENLVPDYWI DGSKRDPLSD FFEVESELGR GATSIVYRCK 
    QKGTQKPYAL KVLKKTVDKK IVRTEIGVLL RLSHPNIIKL KEIFETPTEI SLVLELVTGG 
    ELFDRIVEKG YYSERDAADA VKQILEAVAY LHENGIVHRD LKPENLLYAT PAPDAPLKIA 
    DFGLSKIVEH QVLMKTVCGT PGYCAPEILR GCAYGPEVDM WSVGIITYIL LCGFEPFYDE 
    RGDQFMFRRI LNCEYYFISP WWDEVSLNAK DLVKKLIVLD PKKRLTTFQA LQHPWVTGKA 
    ANFVHMDTAQ KKLQEFNARR KLKAAVKAVV ASSRLGSASS SHTNIQESNK ASSEAQPAQD 
    GKDKTDPLEN KMQAGDHEAA KAAADETMKL QSEEVEEEEG VKEEEEEEEE EEETSRMVPQ 
    EPEDRLETDD QEMKRNSEET LKSVEEEMDP KAEEEAAAVG LGVPPQQDAI LPEY

Genular Protein ID: 3642484810

Symbol: A0A8L2UQP4_RAT

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

  • Length: 502
  • Mass: 55706
  • Checksum: B2E949CC06FECC8E
  • Sequence:
  • MSCAGNDQAA ASGSSSGSGG IFRSPAAKML KVTVPSCPSS PCSSVTSSTE NLVPDYWIDG 
    SKRDPLSDFF EVESELGRGA TSIVYRCKQK GTQKPYALKV LKKTVDKKIV RTEIGVLLRL 
    SHPNIIKLKE IFETPTEISL VLELVTGGEL FDRIVEKGYY SERDAADAVK QILEAVAYLH 
    ENGIVHRDLK PENLLYATPA PDAPLKIADF GLSKIVEHQV LMKTVCGTPG YCAPEILRGC 
    AYGPEVDMWS VGIITYILLC GFEPFYDERG DQFMFRRILN CEYYFISPWW DEVSLNAKDL 
    VKKLIVLDPK KRLTTFQALQ HPWVTGKAAN FVHMDTAQKK LQEFNARRKL KAAVKAVVAS 
    SRLGSASSSH TNIQESNKAS SEAQPAQDGK DKTDPLENKM QAGDHEAAKA AADETMKLQS 
    EEVEEEEGVK EEEEEEEEEE ETSRMVPQEP EDRLETDDQE MKRNSEETLK SVEEEMDPKA 
    EEEAAAVGLG VPPQQDAILP EY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.