Genular: Defining Cellular Identity and Function

Details for: Glp1r

Gene ID: 25051

Symbol: Glp1r

Ensembl ID: ENSRNOG00000001152

Description: glucagon-like peptide 1 receptor

Associated with

Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Associative learning
(GO:0008306)
Camp-mediated signaling
(GO:0019933)
Cell surface receptor signaling pathway
(GO:0007166)
Cellular response to glucagon stimulus
(GO:0071377)
Feeding behavior
(GO:0007631)
Glucagon-like peptide 1 receptor activity
(GO:0044508)
Glucagon receptor activity
(GO:0004967)
G protein-coupled peptide receptor activity
(GO:0008528)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Hormone secretion
(GO:0046879)
Insulin secretion
(GO:0030073)
Learning or memory
(GO:0007611)
Memory
(GO:0007613)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of blood pressure
(GO:0045776)
Negative regulation of neuron apoptotic process
(GO:0043524)
Neuropeptide signaling pathway
(GO:0007218)
Peptide hormone binding
(GO:0017046)
Peptide receptor activity
(GO:0001653)
Plasma membrane
(GO:0005886)
Positive regulation of blood pressure
(GO:0045777)
Positive regulation of cell differentiation
(GO:0045597)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of glucose import
(GO:0046326)
Positive regulation of insulin secretion
(GO:0032024)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Post-translational protein targeting to membrane, translocation
(GO:0031204)
Regulation of calcium ion transport
(GO:0051924)
Regulation of heart contraction
(GO:0008016)
Release of sequestered calcium ion into cytosol
(GO:0051209)
Response to glucose
(GO:0009749)
Response to psychosocial stress
(GO:1990911)

Other Information

Proteins

Glucagon-like peptide 1 receptor

Genular Protein ID: 638416018

Symbol: GLP1R_RAT

Name: Glucagon-like peptide 1 receptor

UniProtKB Accession Codes:

P32301 Q64073 Q6LD83

Database IDs:

Citations:

PubMed ID: 1326760

Title: Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1.

PubMed ID: 1326760

DOI: 10.1073/pnas.89.18.8641

PubMed ID: 7813606

Title: Molecular cloning of a cDNA encoding for the GLP-1 receptor expressed in rat lung.

PubMed ID: 7813606

DOI: 10.1055/s-0029-1211301

Sequence Information:

Length: 463
Mass: 52877
Checksum: ABE2183E8EBE621F
Sequence:

MAVTPSLLRL ALLLLGAVGR AGPRPQGATV SLSETVQKWR EYRHQCQRFL TEAPLLATGL 
FCNRTFDDYA CWPDGPPGSF VNVSCPWYLP WASSVLQGHV YRFCTAEGIW LHKDNSSLPW 
RDLSECEESK QGERNSPEEQ LLSLYIIYTV GYALSFSALV IASAILVSFR HLHCTRNYIH 
LNLFASFILR ALSVFIKDAA LKWMYSTAAQ QHQWDGLLSY QDSLGCRLVF LLMQYCVAAN 
YYWLLVEGVY LYTLLAFSVF SEQRIFKLYL SIGWGVPLLF VIPWGIVKYL YEDEGCWTRN 
SNMNYWLIIR LPILFAIGVN FLVFIRVICI VIAKLKANLM CKTDIKCRLA KSTLTLIPLL 
GTHEVIFAFV MDEHARGTLR FVKLFTELSF TSFQGFMVAV LYCFVNNEVQ MEFRKSWERW 
RLERLNIQRD SSMKPLKCPT SSVSSGATVG SSVYAATCQN SCS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.