Hk1 | ENSRNOG00000046891 | NCBI 25058

Details for: Hk1

Gene ID: 25058

Symbol: Hk1

Ensembl ID: ENSRNOG00000046891

Description: hexokinase 1

Associated with

Glucose metabolism
(R-RNO-70326)
Glycolysis
(R-RNO-70171)
Metabolism
(R-RNO-1430728)
Metabolism of carbohydrates
(R-RNO-71387)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Canonical glycolysis
(GO:0061621)
Carbohydrate phosphorylation
(GO:0046835)
Caveola
(GO:0005901)
Cilium
(GO:0005929)
Cytosol
(GO:0005829)
Establishment of protein localization to mitochondrion
(GO:0072655)
Fructokinase activity
(GO:0008865)
Fructose 6-phosphate metabolic process
(GO:0006002)
Glucokinase activity
(GO:0004340)
Glucosamine kinase activity
(GO:0047931)
Glucose 6-phosphate metabolic process
(GO:0051156)
Glucose binding
(GO:0005536)
Glucose metabolic process
(GO:0006006)
Glycolytic process
(GO:0006096)
Hexokinase activity
(GO:0004396)
Hexose metabolic process
(GO:0019318)
Identical protein binding
(GO:0042802)
Inflammatory response
(GO:0006954)
Innate immune response
(GO:0045087)
Intracellular glucose homeostasis
(GO:0001678)
Maintenance of protein location in mitochondrion
(GO:0072656)
Mannokinase activity
(GO:0019158)
Mannose metabolic process
(GO:0006013)
Membrane raft
(GO:0045121)
Mitochondrial outer membrane
(GO:0005741)
Mitochondrion
(GO:0005739)
Negative regulation of apoptotic process
(GO:0043066)
Peptidoglycan binding
(GO:0042834)
Positive regulation of cytokine production involved in immune response
(GO:0002720)
Positive regulation of interleukin-1 beta production
(GO:0032731)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Response to brassinosteroid
(GO:0009741)
Response to hypoxia
(GO:0001666)
Response to ischemia
(GO:0002931)
Response to ketamine
(GO:1901986)
Sperm principal piece
(GO:0097228)

Other Information

Proteins

HXK1_RAT

Genular Protein ID: 521807901

Symbol: HXK1_RAT

Name: N/A

UniProtKB Accession Codes:

P05708

Database IDs:

Citations:

PubMed ID: 2704734

Title: Complete amino acid sequence of rat brain hexokinase, deduced from the cloned cDNA, and proposed structure of a mammalian hexokinase.

PubMed ID: 2704734

DOI: 10.1073/pnas.86.8.2563

PubMed ID: 3277968

Title: The complete amino acid sequence of the catalytic domain of rat brain hexokinase, deduced from the cloned cDNA.

PubMed ID: 3277968

DOI: 10.1016/s0021-9258(18)69058-1

PubMed ID: 3631958

Title: Rat brain hexokinase: amino acid sequence at the substrate hexose binding site is homologous to that of yeast hexokinase.

PubMed ID: 3631958

DOI: 10.1016/0003-9861(87)90536-4

PubMed ID: 13211595

Title: Substrate specificity of brain hexokinase.

PubMed ID: 13211595

DOI: 10.1016/s0021-9258(18)65384-0

PubMed ID: 5871820

Title: Multiple molecular forms of ATP:hexose 6-phosphotransferase from rat liver.

PubMed ID: 5871820

DOI: 10.1016/0006-291x(64)90038-5

PubMed ID: 7044667

Title: The comparative isozymology of vertebrate hexokinases.

PubMed ID: 7044667

DOI: 10.1016/0305-0491(82)90461-8

PubMed ID: 3579310

Title: Rat brain hexokinase: location of the substrate hexose binding site in a structural domain at the C-terminus of the enzyme.

PubMed ID: 3579310

DOI: 10.1016/0003-9861(87)90116-0

PubMed ID: 19423663

Title: Identification of novel immunodominant epididymal sperm proteins using combinatorial approach.

PubMed ID: 19423663

DOI: 10.1530/rep-09-0052

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 9665168

Title: The structure of mammalian hexokinase-1.

PubMed ID: 9665168

DOI: 10.1038/811

Sequence Information:

Length: 918
Mass: 102408
Checksum: D2200820F0FC41EE
Sequence:

MIAAQLLAYY FTELKDDQVK KIDKYLYAMR LSDEILIDIL TRFKKEMKNG LSRDYNPTAS 
VKMLPTFVRS IPDGSEKGDF IALDLGGSSF RILRVQVNHE KNQNVSMESE IYDTPENIVH 
GSGTQLFDHV ADCLGDFMEK KKIKDKKLPV GFTFSFPCRQ SKIDEAVLIT WTKRFKASGV 
EGADVVKLLN KAIKKRGDYD ANIVAVVNDT VGTMMTCGYD DQQCEVGLII GTGTNACYME 
ELRHIDLVEG DEGRMCINTE WGAFGDDGSL EDIRTEFDRE LDRGSLNPGK QLFEKMVSGM 
YMGELVRLIL VKMAKEGLLF EGRITPELLT RGKFNTSDVS AIEKDKEGIQ NAKEILTRLG 
VEPSDVDCVS VQHICTIVSF RSANLVAATL GAILNRLRDN KGTPRLRTTV GVDGSLYKMH 
PQYSRRFHKT LRRLVPDSDV RFLLSESGTG KGAAMVTAVA YRLAEQHRQI EETLAHFRLS 
KQTLMEVKKR LRTEMEMGLR KETNSKATVK MLPSFVRSIP DGTEHGDFLA LDLGGTNFRV 
LLVKIRSGKK RTVEMHNKIY SIPLEIMQGT GDELFDHIVS CISDFLDYMG IKGPRMPLGF 
TFSFPCHQTN LDCGILISWT KGFKATDCEG HDVASLLRDA VKRREEFDLD VVAVVNDTVG 
TMMTCAYEEP TCEIGLIVGT GTNACYMEEM KNVEMVEGNQ GQMCINMEWG AFGDNGCLDD 
IRTDFDKVVD EYSLNSGKQR FEKMISGMYL GEIVRNILID FTKKGFLFRG QISEPLKTRG 
IFETKFLSQI ESDRLALLQV RAILQQLGLN STCDDSILVK TVCGVVSKRA AQLCGAGMAA 
VVEKIRENRG LDHLNVTVGV DGTLYKLHPH FSRIMHQTVK ELSPKCTVSF LLSEDGSGKG 
AALITAVGVR LRGDPSIA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Hk1

Associated with

Other Information

Complete amino acid sequence of rat brain hexokinase, deduced from the cloned cDNA, and proposed structure of a mammalian hexokinase. PubMed ID: 2704734

The complete amino acid sequence of the catalytic domain of rat brain hexokinase, deduced from the cloned cDNA. PubMed ID: 3277968

Rat brain hexokinase: amino acid sequence at the substrate hexose binding site is homologous to that of yeast hexokinase. PubMed ID: 3631958

Substrate specificity of brain hexokinase. PubMed ID: 13211595

Multiple molecular forms of ATP:hexose 6-phosphotransferase from rat liver. PubMed ID: 5871820

The comparative isozymology of vertebrate hexokinases. PubMed ID: 7044667

Rat brain hexokinase: location of the substrate hexose binding site in a structural domain at the C-terminus of the enzyme. PubMed ID: 3579310

Identification of novel immunodominant epididymal sperm proteins using combinatorial approach. PubMed ID: 19423663

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

The structure of mammalian hexokinase-1. PubMed ID: 9665168