Genular: Defining Cellular Identity and Function

Details for: Scarb1

Gene ID: 25073

Symbol: Scarb1

Ensembl ID: ENSRNOG00000000981

Description: scavenger receptor class B, member 1

Associated with

Binding and uptake of ligands by scavenger receptors
(R-RNO-2173782)
Hdl clearance
(R-RNO-8964011)
Plasma lipoprotein assembly, remodeling, and clearance
(R-RNO-174824)
Plasma lipoprotein clearance
(R-RNO-8964043)
Scavenging by class b receptors
(R-RNO-3000471)
Transport of small molecules
(R-RNO-382551)
Vesicle-mediated transport
(R-RNO-5653656)
Adhesion of symbiont to host
(GO:0044406)
Aflatoxin metabolic process
(GO:0046222)
Amyloid-beta binding
(GO:0001540)
Androgen biosynthetic process
(GO:0006702)
Apical plasma membrane
(GO:0016324)
Apolipoprotein a-i binding
(GO:0034186)
Apolipoprotein binding
(GO:0034185)
Basolateral plasma membrane
(GO:0016323)
Blood vessel endothelial cell migration
(GO:0043534)
Carotenoid transport
(GO:0046867)
Caveola
(GO:0005901)
Cell surface
(GO:0009986)
Cholesterol catabolic process
(GO:0006707)
Cholesterol efflux
(GO:0033344)
Cholesterol homeostasis
(GO:0042632)
Cholesterol import
(GO:0070508)
Cholesterol transport
(GO:0030301)
Cytoplasm
(GO:0005737)
Detection of lipopolysaccharide
(GO:0032497)
Endothelial cell proliferation
(GO:0001935)
High-density lipoprotein particle binding
(GO:0008035)
High-density lipoprotein particle clearance
(GO:0034384)
High-density lipoprotein particle receptor activity
(GO:0070506)
High-density lipoprotein particle remodeling
(GO:0034375)
Identical protein binding
(GO:0042802)
Intestinal lipid absorption
(GO:0098856)
Intracellular membrane-bounded organelle
(GO:0043231)
Lipid binding
(GO:0008289)
Lipid transport
(GO:0006869)
Lipid transporter activity
(GO:0005319)
Lipopolysaccharide-mediated signaling pathway
(GO:0031663)
Lipopolysaccharide binding
(GO:0001530)
Lipopolysaccharide immune receptor activity
(GO:0001875)
Lipopolysaccharide transport
(GO:0015920)
Low-density lipoprotein particle binding
(GO:0030169)
Low-density lipoprotein particle clearance
(GO:0034383)
Lysosome
(GO:0005764)
Membrane
(GO:0016020)
Microvillus membrane
(GO:0031528)
Phagocytosis, recognition
(GO:0006910)
Phosphatidylserine binding
(GO:0001786)
Phospholipid transport
(GO:0015914)
Plasma lipoprotein particle clearance
(GO:0034381)
Plasma membrane
(GO:0005886)
Positive regulation of cholesterol storage
(GO:0010886)
Positive regulation of triglyceride biosynthetic process
(GO:0010867)
Recognition of apoptotic cell
(GO:0043654)
Regulation of phagocytosis
(GO:0050764)
Regulation of phosphatidylcholine catabolic process
(GO:0010899)
Response to vitamin b3
(GO:0033552)
Reverse cholesterol transport
(GO:0043691)
Scavenger receptor activity
(GO:0005044)
Steroid biosynthetic process
(GO:0006694)
Transcytosis
(GO:0045056)
Triglyceride homeostasis
(GO:0070328)
Vitamin transmembrane transport
(GO:0035461)

Other Information

Proteins

Scavenger receptor class B member 1
A6J0X0_RAT

Genular Protein ID: 3608550143

Symbol: SCRB1_RAT

Name: Scavenger receptor class B member 1

UniProtKB Accession Codes:

P97943

Database IDs:

Citations:

PubMed ID: 9177301

Title: Cloning, characterization, and cellular distribution of rat scavenger receptor class B type I (SRBI) in the ovary.

PubMed ID: 9177301

DOI: 10.1006/bbrc.1997.6646

PubMed ID: 12016218

Title: Phosphatidylserine binding of class B scavenger receptor type I, a phagocytosis receptor of testicular Sertoli cells.

PubMed ID: 12016218

DOI: 10.1074/jbc.m202879200

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9291126

Title: Scavenger receptor B1 (SR-B1) substrates inhibit the selective uptake of high-density-lipoprotein cholesteryl esters by rat parenchymal liver cells.

PubMed ID: 9291126

DOI: 10.1042/bj3260515

PubMed ID: 10829064

Title: Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I.

PubMed ID: 10829064

DOI: 10.1073/pnas.100114397

Sequence Information:

Length: 509
Mass: 56957
Checksum: 792A0BBE8D11A105
Sequence:

MGVSSRARWV ALGLGVLGLL CAALGVIMIL MVPSLIKQQV LKNVRIDPSS LSFGMWKEIP 
VPFYLSVYFF EVVNPSEVLN GQKPVVRERG PYVYREFRQK VNITFNDNDT VSYIENRSLR 
FQPDRSQGSE SDYIVLPNIL VLGGAVMMED KPTSLKLLMT LGLVTMGQRA FMNRTVGEIL 
WGYEDPFVNF LSKYFPDMFP IKGKFGLFVG MNDSSSGVFT VFTGVQNFSK IHLVDKWNGL 
SEVNYWHSEQ CNMINGTAGQ MWAPFMTPES SLEFFSPEAC RSMKLTYQES RVFEGIPTYR 
FTAPDTLFAN GSVYPPNEGF CPCRESGIQN VSTCRFGAPL FLSQPHFYNA DPVLSEAVLG 
LNPDPKEHSL FLDIHPVTGI PMNCSVKMQL SLYIKSVKGV GQTGKIEPVV LPLLWFEQSG 
MMGGKTLNTF YTQLVLMPQV LHYAQYVLLG LGGLLLLVPI IYQLRSQEKC FLFWSGSKKG 
SQDKEAMQAY SESLMSPAAK GTVLQEAKL

Genular Protein ID: 3737045435

Symbol: A6J0X0_RAT

Name: N/A

UniProtKB Accession Codes:

A6J0X0

Database IDs:

Citations:

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

Length: 506
Mass: 56371
Checksum: 4D817483D8CF804B
Sequence:

MGVSSRARWV ALGLGVLGLL CAALGVIMIL MVPSLIKQQV LKNVRIDPSS LSFGMWKEIP 
VPFYLSVYFF EVVNPSEVLN GQKPVVRERG PYVYREFRQK VNITFNDNDT VSYIENRSLR 
FQPDRSQGSE SDYIVLPNIL VLGGAVMMED KPTSLKLLMT LGLVTMGQRA FMNRTVGEIL 
WGYEDPFVNF LSKYFPDMFP IKGKFGLFVG MNDSSSGVFT VFTGVQNFSK IHLVDKWNGL 
SEVNYWHSEQ CNMINGTAGQ MWAPFMTPES SLEFFSPEAC RSMKLTYQES RVFEGIPTYR 
FTAPDTLFAN GSVYPPNEGF CPCRESGIQN VSTCRFGAPL FLSQPHFYNA DPVLSEAVLG 
LNPDPKEHSL FLDIHPVTGI PMNCSVKMQL SLYIKSVKGV GQTGKIEPVV LPLLWFEQSG 
MMGGKTLNTF YTQLVLMPQV LHYAQYVLLG LGGLLLLVPI IYQLRSQGPE DTTSPPNLIA 
WSDQPPSPYT PLLEDSLSGQ PASATS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Scarb1

Associated with

Other Information

Cloning, characterization, and cellular distribution of rat scavenger receptor class B type I (SRBI) in the ovary. PubMed ID: 9177301

Phosphatidylserine binding of class B scavenger receptor type I, a phagocytosis receptor of testicular Sertoli cells. PubMed ID: 12016218

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Scavenger receptor B1 (SR-B1) substrates inhibit the selective uptake of high-density-lipoprotein cholesteryl esters by rat parenchymal liver cells. PubMed ID: 9291126

Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I. PubMed ID: 10829064