Genular: Defining Cellular Identity and Function

Details for: Apoa4

Gene ID: 25080

Symbol: Apoa4

Ensembl ID: ENSRNOG00000055909

Description: apolipoprotein A4

Associated with

Chylomicron assembly
(R-RNO-8963888)
Chylomicron remodeling
(R-RNO-8963901)
Metabolism
(R-RNO-1430728)
Metabolism of fat-soluble vitamins
(R-RNO-6806667)
Metabolism of vitamins and cofactors
(R-RNO-196854)
Plasma lipoprotein assembly
(R-RNO-8963898)
Plasma lipoprotein assembly, remodeling, and clearance
(R-RNO-174824)
Plasma lipoprotein remodeling
(R-RNO-8963899)
Retinoid metabolism and transport
(R-RNO-975634)
Sensory perception
(R-RNO-9709957)
Transport of small molecules
(R-RNO-382551)
Visual phototransduction
(R-RNO-2187338)
Acylglycerol homeostasis
(GO:0055090)
Antioxidant activity
(GO:0016209)
Cell surface
(GO:0009986)
Cholesterol efflux
(GO:0033344)
Cholesterol homeostasis
(GO:0042632)
Cholesterol metabolic process
(GO:0008203)
Cholesterol transfer activity
(GO:0120020)
Chylomicron
(GO:0042627)
Copper ion binding
(GO:0005507)
Extracellular space
(GO:0005615)
Extracellular vesicle
(GO:1903561)
High-density lipoprotein particle
(GO:0034364)
High-density lipoprotein particle remodeling
(GO:0034375)
Hydrogen peroxide catabolic process
(GO:0042744)
Identical protein binding
(GO:0042802)
Innate immune response in mucosa
(GO:0002227)
Intermembrane lipid transfer
(GO:0120009)
Leukocyte cell-cell adhesion
(GO:0007159)
Lipid binding
(GO:0008289)
Lipid catabolic process
(GO:0016042)
Lipid homeostasis
(GO:0055088)
Lipid transport
(GO:0006869)
Lipoprotein metabolic process
(GO:0042157)
Low-density lipoprotein particle
(GO:0034362)
Negative regulation of plasma lipoprotein oxidation
(GO:0034445)
Peripheral nervous system axon regeneration
(GO:0014012)
Phosphatidylcholine-sterol o-acyltransferase activator activity
(GO:0060228)
Phosphatidylcholine binding
(GO:0031210)
Phosphatidylcholine metabolic process
(GO:0046470)
Phospholipid binding
(GO:0005543)
Phospholipid efflux
(GO:0033700)
Positive regulation of fatty acid biosynthetic process
(GO:0045723)
Positive regulation of triglyceride catabolic process
(GO:0010898)
Protein-lipid complex assembly
(GO:0065005)
Protein homodimerization activity
(GO:0042803)
Regulation of cholesterol transport
(GO:0032374)
Regulation of intestinal cholesterol absorption
(GO:0030300)
Removal of superoxide radicals
(GO:0019430)
Response to food
(GO:0032094)
Response to lipid hydroperoxide
(GO:0006982)
Response to stilbenoid
(GO:0035634)
Response to triglyceride
(GO:0034014)
Reverse cholesterol transport
(GO:0043691)
Synapse
(GO:0045202)
Very-low-density lipoprotein particle
(GO:0034361)
Very-low-density lipoprotein particle remodeling
(GO:0034372)

Other Information

Proteins

Apolipoprotein A-IV

Genular Protein ID: 2783650109

Symbol: APOA4_RAT

Name: Apolipoprotein A-IV

UniProtKB Accession Codes:

P02651 Q5BK92

Database IDs:

Citations:

PubMed ID: 3009456

Title: Evolution of the apolipoproteins. Structure of the rat apo-A-IV gene and its relationship to the human genes for apo-A-I, C-III, and E.

PubMed ID: 3009456

DOI: 10.1016/s0021-9258(19)84575-1

PubMed ID: 6591177

Title: Rat apolipoprotein A-IV contains 13 tandem repetitions of a 22-amino acid segment with amphipathic helical potential.

PubMed ID: 6591177

DOI: 10.1073/pnas.81.16.5021

PubMed ID: 3020028

Title: Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes.

PubMed ID: 3020028

DOI: 10.1016/s0021-9258(18)69300-7

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 391
Mass: 44456
Checksum: 24095004A809201D
Sequence:

MFLKAVVLTV ALVAITGTQA EVTSDQVANV MWDYFTQLSN NAKEAVEQLQ KTDVTQQLNT 
LFQDKLGNIN TYADDLQNKL VPFAVQLSGH LTKETERVRE EIQKELEDLR ANMMPHANKV 
SQMFGDNVQK LQEHLRPYAT DLQAQINAQT QDMKRQLTPY IQRMQTTIQD NVENLQSSMV 
PFANELKEKF NQNMEGLKGQ LTPRANELKA TIDQNLEDLR SRLAPLAEGV QEKLNHQMEG 
LAFQMKKNAE ELQTKVSTNI DQLQKNLAPL VEDVQSKLKG NTEGLQKSLE DLNKQLDQQV 
EVFRRAVEPL GDKFNMALVQ QMEKFRQQLG SDSGDVESHL SFLEKNLREK VSSFMSTLQK 
KGSPDQPLAL PLPEQVQEQV QEQVQPKPLE S

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Apoa4

Associated with

Other Information

Evolution of the apolipoproteins. Structure of the rat apo-A-IV gene and its relationship to the human genes for apo-A-I, C-III, and E. PubMed ID: 3009456

Rat apolipoprotein A-IV contains 13 tandem repetitions of a 22-amino acid segment with amphipathic helical potential. PubMed ID: 6591177

Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes. PubMed ID: 3020028