Genular: Defining Cellular Identity and Function

Details for: Apoa1

Gene ID: 25081

Symbol: Apoa1

Ensembl ID: ENSRNOG00000045679

Description: apolipoprotein A1

Associated with

Abc-family proteins mediated transport
(R-RNO-382556)
Abc transporters in lipid homeostasis
(R-RNO-1369062)
Binding and uptake of ligands by scavenger receptors
(R-RNO-2173782)
Cellular responses to stimuli
(R-RNO-8953897)
Cellular responses to stress
(R-RNO-2262752)
Chylomicron assembly
(R-RNO-8963888)
Chylomicron remodeling
(R-RNO-8963901)
Hdl assembly
(R-RNO-8963896)
Hdl clearance
(R-RNO-8964011)
Hdl remodeling
(R-RNO-8964058)
Heme signaling
(R-RNO-9707616)
Hemostasis
(R-RNO-109582)
Metabolism
(R-RNO-1430728)
Metabolism of fat-soluble vitamins
(R-RNO-6806667)
Metabolism of proteins
(R-RNO-392499)
Metabolism of vitamins and cofactors
(R-RNO-196854)
Plasma lipoprotein assembly
(R-RNO-8963898)
Plasma lipoprotein assembly, remodeling, and clearance
(R-RNO-174824)
Plasma lipoprotein clearance
(R-RNO-8964043)
Plasma lipoprotein remodeling
(R-RNO-8963899)
Platelet activation, signaling and aggregation
(R-RNO-76002)
Platelet degranulation
(R-RNO-114608)
Post-translational protein modification
(R-RNO-597592)
Post-translational protein phosphorylation
(R-RNO-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-RNO-381426)
Response to elevated platelet cytosolic ca2+
(R-RNO-76005)
Retinoid metabolism and transport
(R-RNO-975634)
Scavenging by class a receptors
(R-RNO-3000480)
Scavenging by class b receptors
(R-RNO-3000471)
Scavenging of heme from plasma
(R-RNO-2168880)
Sensory perception
(R-RNO-9709957)
Transport of small molecules
(R-RNO-382551)
Vesicle-mediated transport
(R-RNO-5653656)
Visual phototransduction
(R-RNO-2187338)
Adrenal gland development
(GO:0030325)
Amyloid-beta binding
(GO:0001540)
Animal organ regeneration
(GO:0031100)
Apolipoprotein a-i receptor binding
(GO:0034191)
Apolipoprotein receptor binding
(GO:0034190)
Axon regeneration
(GO:0031103)
Blood vessel endothelial cell migration
(GO:0043534)
Chemorepellent activity
(GO:0045499)
Cholesterol binding
(GO:0015485)
Cholesterol biosynthetic process
(GO:0006695)
Cholesterol efflux
(GO:0033344)
Cholesterol homeostasis
(GO:0042632)
Cholesterol metabolic process
(GO:0008203)
Cholesterol transfer activity
(GO:0120020)
Cholesterol transport
(GO:0030301)
Endothelial cell proliferation
(GO:0001935)
Enzyme binding
(GO:0019899)
Glucocorticoid metabolic process
(GO:0008211)
G protein-coupled receptor signaling pathway
(GO:0007186)
Heat shock protein binding
(GO:0031072)
High-density lipoprotein particle assembly
(GO:0034380)
High-density lipoprotein particle binding
(GO:0008035)
High-density lipoprotein particle receptor binding
(GO:0070653)
High-density lipoprotein particle remodeling
(GO:0034375)
Identical protein binding
(GO:0042802)
Integrin-mediated signaling pathway
(GO:0007229)
Lipase inhibitor activity
(GO:0055102)
Lipid binding
(GO:0008289)
Lipid storage
(GO:0019915)
Lipid transporter activity
(GO:0005319)
Lipoprotein biosynthetic process
(GO:0042158)
Lipoprotein metabolic process
(GO:0042157)
Lipoprotein particle binding
(GO:0071813)
Negative chemotaxis
(GO:0050919)
Negative regulation of cytokine production involved in immune response
(GO:0002719)
Negative regulation of heterotypic cell-cell adhesion
(GO:0034115)
Negative regulation of inflammatory response
(GO:0050728)
Negative regulation of interleukin-1 beta production
(GO:0032691)
Negative regulation of tumor necrosis factor-mediated signaling pathway
(GO:0010804)
Negative regulation of very-low-density lipoprotein particle remodeling
(GO:0010903)
Peripheral nervous system axon regeneration
(GO:0014012)
Phosphatidylcholine-sterol o-acyltransferase activator activity
(GO:0060228)
Phosphatidylcholine biosynthetic process
(GO:0006656)
Phospholipid binding
(GO:0005543)
Phospholipid efflux
(GO:0033700)
Phospholipid metabolic process
(GO:0006644)
Phospholipid transport
(GO:0015914)
Positive regulation of cholesterol efflux
(GO:0010875)
Positive regulation of phagocytosis
(GO:0050766)
Positive regulation of rho protein signal transduction
(GO:0035025)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Protein localization
(GO:0008104)
Protein stabilization
(GO:0050821)
Regulation of cdc42 protein signal transduction
(GO:0032489)
Regulation of intestinal cholesterol absorption
(GO:0030300)
Regulation of protein phosphorylation
(GO:0001932)
Response to estrogen
(GO:0043627)
Response to nutrient
(GO:0007584)
Response to xenobiotic stimulus
(GO:0009410)
Reverse cholesterol transport
(GO:0043691)
Signaling receptor binding
(GO:0005102)
Transforming growth factor beta receptor signaling pathway
(GO:0007179)

Other Information

Proteins

Apolipoprotein A-I

Genular Protein ID: 1261815116

Symbol: APOA1_RAT

Name: Apolipoprotein A-I

UniProtKB Accession Codes:

P04639 O08877 O09054 Q5EBB2

Database IDs:

Citations:

PubMed ID: 6426956

Title: Cloning and structure analysis of the rat apolipoprotein A-I cDNA.

PubMed ID: 6426956

DOI: 10.1111/j.1432-1033.1984.tb08129.x

PubMed ID: 3020028

Title: Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes.

PubMed ID: 3020028

DOI: 10.1016/s0021-9258(18)69300-7

PubMed ID: 9415807

Title: Repetitive elements in the third intron of murine apolipoprotein A-I gene.

PubMed ID: 9415807

DOI: 10.1080/15216549700204801

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6798036

Title: The primary translation product of rat intestinal apolipoprotein A-I mRNA is an unusual preproprotein.

PubMed ID: 6798036

DOI: 10.1016/s0021-9258(19)68295-5

Sequence Information:

Length: 259
Mass: 30062
Checksum: 28538891B2E3A6CD
Sequence:

MKAAVLAVAL VFLTGCQAWE FWQQDEPQSQ WDRVKDFATV YVDAVKDSGR DYVSQFESST 
LGKQLNLNLL DNWDTLGSTV GRLQEQLGPV TQEFWANLEK ETDWLRNEMN KDLENVKQKM 
QPHLDEFQEK WNEEVEAYRQ KLEPLGTELH KNAKEMQRHL KVVAEEFRDR MRVNADALRA 
KFGLYSDQMR ENLAQRLTEI KNHPTLIEYH TKASDHLKTL GEKAKPALDD LGQGLMPVLE 
AWKAKIMSMI DEAKKKLNA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Apoa1

Associated with

Other Information

Cloning and structure analysis of the rat apolipoprotein A-I cDNA. PubMed ID: 6426956

Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes. PubMed ID: 3020028

Repetitive elements in the third intron of murine apolipoprotein A-I gene. PubMed ID: 9415807