Genular: Defining Cellular Identity and Function

Details for: Itga1

Gene ID: 25118

Symbol: Itga1

Ensembl ID: ENSRNOG00000053550

Description: integrin subunit alpha 1

Associated with

Extracellular matrix organization
(R-RNO-1474244)
Integrin cell surface interactions
(R-RNO-216083)
Muscle contraction
(R-RNO-397014)
Smooth muscle contraction
(R-RNO-445355)
Acrosomal vesicle
(GO:0001669)
Basal part of cell
(GO:0045178)
Cell-cell adhesion
(GO:0098609)
Cell-matrix adhesion
(GO:0007160)
Cell adhesion
(GO:0007155)
Cell adhesion mediated by integrin
(GO:0033627)
Cell chemotaxis
(GO:0060326)
Cell surface
(GO:0009986)
Cellular extravasation
(GO:0045123)
Collagen binding
(GO:0005518)
Collagen binding involved in cell-matrix adhesion
(GO:0098639)
External side of plasma membrane
(GO:0009897)
Focal adhesion
(GO:0005925)
Integrin-mediated signaling pathway
(GO:0007229)
Integrin alpha1-beta1 complex
(GO:0034665)
Integrin binding
(GO:0005178)
Integrin complex
(GO:0008305)
Metal ion binding
(GO:0046872)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of epidermal growth factor receptor signaling pathway
(GO:0042059)
Neuron projection morphogenesis
(GO:0048812)
Neutrophil chemotaxis
(GO:0030593)
Perikaryon
(GO:0043204)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of neuron apoptotic process
(GO:0043525)
Protein phosphatase binding
(GO:0019903)
Signaling receptor binding
(GO:0005102)
Vasodilation
(GO:0042311)

Other Information

Proteins

Integrin alpha-1

Genular Protein ID: 3435248471

Symbol: ITA1_RAT

Name: Integrin alpha-1

UniProtKB Accession Codes:

P18614

Database IDs:

Citations:

PubMed ID: 2380249

Title: Molecular cloning of the rat integrin alpha 1-subunit: a receptor for laminin and collagen.

PubMed ID: 2380249

DOI: 10.1083/jcb.111.2.709

PubMed ID: 24090084

Title: Site-specific glycan-peptide analysis for determination of N-glycoproteome heterogeneity.

PubMed ID: 24090084

DOI: 10.1021/pr400783j

PubMed ID: 10386626

Title: Crystal structure of the alpha1beta1 integrin I-domain: insights into integrin I-domain function.

PubMed ID: 10386626

DOI: 10.1016/s0014-5793(99)00666-3

Sequence Information:

Length: 1180
Mass: 130809
Checksum: 8E5DA2BE02362EE4
Sequence:

MVPRRPASLE VTVACIWLLT VILGFCVSFN VDVKNSMSFS GPVEDMFGYT VQQYENEEGK 
WVLIGSPLVG QPKARTGDVY KCPVGRERAM PCVKLDLPVN TSIPNVTEIK ENMTFGSTLV 
TNPNGGFLAC GPLYAYRCGH LHYTTGICSD VSPTFQVVNS FAPVQECSTQ LDIVIVLDGS 
NSIYPWESVI AFLNDLLKRM DIGPKQTQVG IVQYGENVTH EFNLNKYSST EEVLVAANKI 
GRQGGLQTMT ALGIDTARKE AFTEARGARR GVKKVMVIVT DGESHDNYRL KQVIQDCEDE 
NIQRFSIAIL GHYNRGNLST EKFVEEIKSI ASEPTEKHFF NVSDELALVT IVKALGERIF 
ALEATADQSA ASFEMEMSQT GFSAHYSQDW VMLGAVGAYD WNGTVVMQKA NQMVIPHNTT 
FQTEPAKMNE PLASYLGYTV NSATIPGDVL YIAGQPRYNH TGQVVIYKME DGNINILQTL 
GGEQIGSYFG SVLTTIDIDK DSYTDLLLVG APMYMGTEKE EQGKVYVYAV NQTRFEYQMS 
LEPIRQTCCS SLKDNSCTKE NKNEPCGARF GTAIAAVKDL NVDGFNDVVI GAPLEDDHAG 
AVYIYHGSGK TIREAYAQRI PSGGDGKTLK FFGQSIHGEM DLNGDGLTDV TIGGLGGAAL 
FWARDVAVVK VTMNFEPNKV NIQKKNCRVE GKETVCINAT MCFHVKLKSK EDSIYEADLQ 
YRVTLDSLRQ ISRSFFSGTQ ERKIQRNITV RESECIRHSF YMLDKHDFQD SVRVTLDFNL 
TDPENGPVLD DALPNSVHEH IPFAKDCGNK ERCISDLTLN VSTTEKSLLI VKSQHDKFNV 
SLTVKNKGDS AYNTRTVVQH SPNLIFSGIE EIQKDSCESN QNITCRVGYP FLRAGETVTF 
KIIFQFNTSH LSENAIIHLS ATSDSEEPLE SLNDNEVNIS IPVKYEVGLQ FYSSASEHHI 
SVAANETIPE FINSTEDIGN EINVFYTIRK RGHFPMPELQ LSISFPNLTA DGYPVLYPIG 
WSSSDNVNCR PRSLEDPFGI NSGKKMTISK SEVLKRGTIQ DCSSTCGVAT ITCSLLPSDL 
SQVNVSLLLW KPTFIRAHFS SLNLTLRGEL KSENSSLTLS SSNRKRELAI QISKDGLPGR 
VPLWVILLSA FAGLLLLMLL ILALWKIGFF KRPLKKKMEK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.