Details for: Aanat

Gene ID: 25120

Symbol: Aanat

Ensembl ID: ENSRNOG00000011182

Description: aralkylamine N-acetyltransferase

Associated with

Other Information

Genular Protein ID: 3592539439

Symbol: SNAT_RAT

Name: Serotonin N-acetyltransferase

UniProtKB Accession Codes:

Q64666 Q4JL74 Q64553

Database IDs:

AGR 1 AlphaFoldDB 1 BRENDA 1 Bgee 1 BindingDB 1 CTD 1 ChEBI 8 ChEMBL 1 EC 1 EMBL 4 Ensembl 4 GO 23 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 1 RefSeq 3 Rhea 1 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UniPathway 1 UniProtKB 3 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8770929

Title: Melatonin synthesis: analysis of the more than 150-fold nocturnal increase in serotonin N-acetyltransferase messenger ribonucleic acid in the rat pineal gland.

PubMed ID: 8770929

DOI: 10.1210/endo.137.7.8770929

PubMed ID: 8524412

Title: Diurnal variation in mRNA encoding serotonin N-acetyltransferase in pineal gland.

PubMed ID: 8524412

DOI: 10.1038/378783a0

PubMed ID: 7502081

Title: Pineal serotonin N-acetyltransferase: expression cloning and molecular analysis.

PubMed ID: 7502081

DOI: 10.1126/science.270.5242.1681

PubMed ID: 11427721

Title: Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis.

PubMed ID: 11427721

DOI: 10.1073/pnas.141118798

PubMed ID: 16099857

Title: Proteasomal proteolysis in the adrenergic induction of arylalkylamine-N-acetyltransferase in rat pinealocytes.

PubMed ID: 16099857

DOI: 10.1210/en.2005-0642

PubMed ID: 19103603

Title: Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling.

PubMed ID: 19103603

DOI: 10.1074/jbc.m808394200

PubMed ID: 20210853

Title: N-terminal residues regulate proteasomal degradation of AANAT.

PubMed ID: 20210853

DOI: 10.1111/j.1600-079x.2010.00753.x

Sequence Information:

  • Length: 205
  • Mass: 23142
  • Checksum: 2504E3082A26BF8E
  • Sequence:
    • MLSIHPLKPE ALHLPLGTSE FLGCQRRHTL PASEFRCLTP EDATSAFEIE REAFISVSGT 
CPLHLDEIRH FLTLCPELSL GWFEEGCLVA FIIGSLWDKE RLTQESLTLH RPGGRTAHLH 
VLAVHRTFRQ QGKGSVLLWR YLHHLGSQPA VRRAVLMCEN ALVPFYEKFG FQAMGPCAIT 
MGSLTFTELQ CSLRCHTFLR RNSGC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.