Stat3 | ENSRNOG00000019742 | NCBI 25125

Details for: Stat3

Gene ID: 25125

Symbol: Stat3

Ensembl ID: ENSRNOG00000019742

Description: signal transducer and activator of transcription 3

Associated with

Antiviral mechanism by ifn-stimulated genes
(R-RNO-1169410)
Cytokine signaling in immune system
(R-RNO-1280215)
Downstream signal transduction
(R-RNO-186763)
Immune system
(R-RNO-168256)
Interferon signaling
(R-RNO-913531)
Interleukin-1 family signaling
(R-RNO-446652)
Interleukin-2 family signaling
(R-RNO-451927)
Interleukin-4 and interleukin-13 signaling
(R-RNO-6785807)
Interleukin-6 family signaling
(R-RNO-6783589)
Interleukin-6 signaling
(R-RNO-1059683)
Interleukin-7 signaling
(R-RNO-1266695)
Interleukin-9 signaling
(R-RNO-8985947)
Interleukin-10 signaling
(R-RNO-6783783)
Interleukin-12 family signaling
(R-RNO-447115)
Interleukin-15 signaling
(R-RNO-8983432)
Interleukin-20 family signaling
(R-RNO-8854691)
Interleukin-21 signaling
(R-RNO-9020958)
Interleukin-23 signaling
(R-RNO-9020933)
Interleukin-27 signaling
(R-RNO-9020956)
Interleukin-35 signalling
(R-RNO-8984722)
Interleukin-37 signaling
(R-RNO-9008059)
Met activates stat3
(R-RNO-8875791)
Pkr-mediated signaling
(R-RNO-9833482)
Ptk6 activates stat3
(R-RNO-8849474)
Signaling by alk
(R-RNO-201556)
Signaling by interleukins
(R-RNO-449147)
Signaling by met
(R-RNO-6806834)
Signaling by non-receptor tyrosine kinases
(R-RNO-9006927)
Signaling by pdgf
(R-RNO-186797)
Signaling by ptk6
(R-RNO-8848021)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signaling by scf-kit
(R-RNO-1433557)
Signal transduction
(R-RNO-162582)
Stat3 nuclear events downstream of alk signaling
(R-RNO-9701898)
Acute-phase response
(GO:0006953)
Ccr5 chemokine receptor binding
(GO:0031730)
Cell differentiation
(GO:0030154)
Cell population proliferation
(GO:0008283)
Cellular response to hormone stimulus
(GO:0032870)
Chromatin dna binding
(GO:0031490)
Defense response
(GO:0006952)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription factor binding
(GO:0140297)
Dna binding
(GO:0003677)
Eye photoreceptor cell differentiation
(GO:0001754)
Gene expression
(GO:0010467)
Identical protein binding
(GO:0042802)
Inflammatory response
(GO:0006954)
Intracellular receptor signaling pathway
(GO:0030522)
Leptin-mediated signaling pathway
(GO:0033210)
Negative regulation of autophagy
(GO:0010507)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of hydrogen peroxide biosynthetic process
(GO:0010730)
Nuclear glucocorticoid receptor binding
(GO:0035259)
Nuclear receptor activity
(GO:0004879)
Phosphorylation
(GO:0016310)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of interleukin-1 beta production
(GO:0032731)
Positive regulation of interleukin-6 production
(GO:0032755)
Positive regulation of interleukin-8 production
(GO:0032757)
Positive regulation of interleukin-10 production
(GO:0032733)
Positive regulation of tumor necrosis factor production
(GO:0032760)
Positive regulation of vascular endothelial growth factor production
(GO:0010575)
Primary mirna binding
(GO:0070878)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Protein homodimerization activity
(GO:0042803)
Protein import into nucleus
(GO:0006606)
Protein kinase binding
(GO:0019901)
Protein phosphatase binding
(GO:0019903)
Receptor signaling pathway via jak-stat
(GO:0007259)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to estradiol
(GO:0032355)
Response to ischemia
(GO:0002931)
Response to organic cyclic compound
(GO:0014070)
Response to organic substance
(GO:0010033)
Response to xenobiotic stimulus
(GO:0009410)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna sequestering activity
(GO:0140610)
Sequence-specific dna binding
(GO:0043565)
Sexual reproduction
(GO:0019953)
Signaling adaptor activity
(GO:0035591)
Signaling receptor binding
(GO:0005102)
Temperature homeostasis
(GO:0001659)
Transcription by rna polymerase ii
(GO:0006366)
Transcription cis-regulatory region binding
(GO:0000976)
Transforming growth factor beta receptor signaling pathway
(GO:0007179)

Other Information

Proteins

Signal transducer and activator of transcription 3

Genular Protein ID: 2139975786

Symbol: STAT3_RAT

Name: Signal transducer and activator of transcription 3

UniProtKB Accession Codes:

P52631

Database IDs:

Citations:

PubMed ID: 8530402

Title: Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements.

PubMed ID: 8530402

DOI: 10.1074/jbc.270.50.29998

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19427337

Title: Caveolin-2 regulation of STAT3 transcriptional activation in response to insulin.

PubMed ID: 19427337

DOI: 10.1016/j.bbamcr.2009.04.015

Sequence Information:

Length: 770
Mass: 88040
Checksum: D74A0C76954754ED
Sequence:

MAQWNQLQQL DTRYLEQLHQ LYSDSFPMEL RQFLAPWIES QDWAYAASKE SHATLVFHNL 
LGEIDQQYSR FLQESNVLYQ HNLRRIKQFL QSRYLEKPME IARIVARCLW EESRLLQTAA 
TAAQQGGQAN HPTAAVVTEK QQMLEQHLQD VRKRVQDLEQ KMKVVENLQD DFDFNYKTLK 
SQGDMQDLNG NNQSVTRQKM QQLEQMLTAL DQMRRSIVSE LAGLLSAMEY VQKTLTDEEL 
ADWKRRQQIA CIGGPPNICL DRLENWITSL AESQLQTRQQ IKKLEELQQK VSYKGDPIVQ 
HRPMLEERIV DLFRNLMKSA FVVERQPCMP MHPDRPLVIK TGVQFTTKVR LLVKFPELNY 
QLKIKVCIDK DSGDVAALRG SRKFNILGTN TKVMNMEESN NGSLSAEFKH LTLREQRCGN 
GGRANCDASL IVTEELHLIT FETEVYHQGL KIDLETHSLP VVVISNICQM PNAWASILWY 
NMLTNNPKNV NFFTKPPIGT WDQVAEVLSW QFSSTTKRGL SIEQLTTLAE KLLGPGVNYS 
GCQITWAKFC KENMAGKGFS FWVWLDNIID LVKKYILALW NEGYIMGFIS KERERAILST 
KPPGTFLLRF SESSKEGGVT FTWVEKDISG KTQIQSVEPY TKQQLNNMSF AEIIMGYKIM 
DATNILVSPL VYLYPDIPKE EAFGKYCRPE SQEHPEADPG SAAPYLKTKF ICVTPTTCSN 
TIDLPMSPRT LDSLMQFGNN GEGAEPSAGG QFESLTFDMD LTSECATSPM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.