Genular: Defining Cellular Identity and Function

Details for: Vav1

Gene ID: 25156

Symbol: Vav1

Ensembl ID: ENSRNOG00000050430

Description: vav guanine nucleotide exchange factor 1

Associated with

Adaptive immune system
(R-RNO-1280218)
Antigen activates b cell receptor (bcr) leading to generation of second messengers
(R-RNO-983695)
Azathioprine adme
(R-RNO-9748787)
Cd28 co-stimulation
(R-RNO-389356)
Cd28 dependent vav1 pathway
(R-RNO-389359)
Cell death signalling via nrage, nrif and nade
(R-RNO-204998)
Costimulation by the cd28 family
(R-RNO-388841)
Cytokine signaling in immune system
(R-RNO-1280215)
Death receptor signaling
(R-RNO-73887)
Drug adme
(R-RNO-9748784)
Erythropoietin activates ras
(R-RNO-9027284)
Fc epsilon receptor (fceri) signaling
(R-RNO-2454202)
Fceri mediated ca+2 mobilization
(R-RNO-2871809)
Fceri mediated mapk activation
(R-RNO-2871796)
Fcgamma receptor (fcgr) dependent phagocytosis
(R-RNO-2029480)
G alpha (12/13) signalling events
(R-RNO-416482)
Gpcr downstream signalling
(R-RNO-388396)
Gpvi-mediated activation cascade
(R-RNO-114604)
Hemostasis
(R-RNO-109582)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Interleukin-3, interleukin-5 and gm-csf signaling
(R-RNO-512988)
Intracellular signaling by second messengers
(R-RNO-9006925)
Negative regulation of the pi3k/akt network
(R-RNO-199418)
Nrage signals death through jnk
(R-RNO-193648)
P75 ntr receptor-mediated signalling
(R-RNO-193704)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-RNO-6811558)
Pip3 activates akt signaling
(R-RNO-1257604)
Platelet activation, signaling and aggregation
(R-RNO-76002)
Rac1 gtpase cycle
(R-RNO-9013149)
Rac2 gtpase cycle
(R-RNO-9013404)
Regulation of actin dynamics for phagocytic cup formation
(R-RNO-2029482)
Regulation of signaling by cbl
(R-RNO-912631)
Rhoa gtpase cycle
(R-RNO-8980692)
Rhog gtpase cycle
(R-RNO-9013408)
Rho gtpase cycle
(R-RNO-9012999)
Signaling by erythropoietin
(R-RNO-9006335)
Signaling by gpcr
(R-RNO-372790)
Signaling by interleukins
(R-RNO-449147)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signaling by rho gtpases
(R-RNO-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-RNO-9716542)
Signaling by scf-kit
(R-RNO-1433557)
Signaling by the b cell receptor (bcr)
(R-RNO-983705)
Signaling by vegf
(R-RNO-194138)
Signal transduction
(R-RNO-162582)
Vegfa-vegfr2 pathway
(R-RNO-4420097)
Vegfr2 mediated vascular permeability
(R-RNO-5218920)
Cell-cell junction
(GO:0005911)
Cell development
(GO:0048468)
Cell migration
(GO:0016477)
Cell surface receptor signaling pathway
(GO:0007166)
Cytoplasm
(GO:0005737)
G protein-coupled receptor signaling pathway
(GO:0007186)
Guanyl-nucleotide exchange factor activity
(GO:0005085)
Immune response
(GO:0006955)
Immune response-regulating cell surface receptor signaling pathway
(GO:0002768)
Integrin-mediated signaling pathway
(GO:0007229)
Intracellular signal transduction
(GO:0035556)
Metal ion binding
(GO:0046872)
Neutrophil chemotaxis
(GO:0030593)
Phagocytosis
(GO:0006909)
Phosphorylation-dependent protein binding
(GO:0140031)
Phosphotyrosine residue binding
(GO:0001784)
Positive regulation of cell adhesion
(GO:0045785)
Positive regulation of natural killer cell mediated cytotoxicity
(GO:0045954)
Reactive oxygen species metabolic process
(GO:0072593)
Regulation of cell size
(GO:0008361)
Regulation of gtpase activity
(GO:0043087)
T cell activation
(GO:0042110)
T cell differentiation
(GO:0030217)

Other Information

Proteins

Q5BK91_RAT

Genular Protein ID: 996869135

Symbol: Q5BK91_RAT

Name: N/A

UniProtKB Accession Codes:

Q5BK91

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

Length: 843
Mass: 97971
Checksum: 33C5CB8F3095CA46
Sequence:

MELWRQCTHW LIQCRVLPPS HRVTWEGAQV CELAQALRDG VLLCQLLNNL LPHAINLREV 
NLWPQMSQFL CLKNIRTFLS TCCEKFGLKR SELFEAFDLF DVQDFGKVIY TLSALSWTPI 
AQNKGIMPFP TEDSALGDED IYSGLSDQID DTAEEDEDLY DCVENEEAEG DEIYEDLMRS 
ESVPTPPKMT EYDKRCCCLR EIQQTEEKYT DTLGSIQQHF MKPLQRFLKP QDMETIFVNI 
EELLSVHTHF LKELKDALSG PGATMLYQVF IKYKERFLVY GRYCSQVESA SKHLDQVATA 
REDVQMKLEE CSQRANNGRF TLRDLLMVPM QRVLKYHLLL QELVKHTQDT TEKENLRLAL 
DAMRDLAQCV NEVKRDNETL RQITNFQLSI ENLDQSLANY GRPKIDGELK ITSVERRSKT 
DRYAFLLDKA LLICKRRGDS YDLKASVNLH SFQVRDDSSG ERDNKKWSHM FLLIEDQGAQ 
GYELFFKTRE LKKKWMEQFE MAISNIYPEN ATANGHDFQM FSFEETTSCK ACQMLLRGTF 
YQGYRCYRCR APAHKECLGR VPPCGRQDFS GTMKKDKLHR RAQDKKRNEL GLPKMEVCQE 
YYGIPPPPGA FGPFLRLNPG DIVELTKAEA EHNWWEGRNT ATNEVGWFPC NRVRPYVHGP 
PQDLSVHLWY AGPMERAGAE GILTNRSDGT YLVRQRVKDT AEFAISIKYN VEVKHIKIMT 
SEGLYRITEK KAFRGLPELV EFYQQNSLKD CFKSLDTTLQ FPYKEPERRA INKPPVGSTK 
YFGTAKARYD FCARDRSELS LKEGDIIKIL NKKGQQGWWR GEIYGRIGWF PSNYVEEDYS 
EYC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Vav1

Associated with

Other Information

Genome sequence of the Brown Norway rat yields insights into mammalian evolution. PubMed ID: 15057822

Database document:

PubMed ID: 15057822