Details for: Gata2

Gene ID: 25159

Symbol: Gata2

Ensembl ID: ENSRNOG00000012347

Description: GATA binding protein 2

Associated with

  • Factors involved in megakaryocyte development and platelet production
    (R-RNO-983231)
  • Gene expression (transcription)
    (R-RNO-74160)
  • Generic transcription pathway
    (R-RNO-212436)
  • Hemostasis
    (R-RNO-109582)
  • Rna polymerase ii transcription
    (R-RNO-73857)
  • Runx1 regulates transcription of genes involved in differentiation of hscs
    (R-RNO-8939236)
  • Transcriptional regulation by runx1
    (R-RNO-8878171)
  • Angiogenesis
    (GO:0001525)
  • Brown fat cell differentiation
    (GO:0050873)
  • C2h2 zinc finger domain binding
    (GO:0070742)
  • Cell differentiation in hindbrain
    (GO:0021533)
  • Cell fate commitment
    (GO:0045165)
  • Cell fate determination
    (GO:0001709)
  • Central nervous system neuron development
    (GO:0021954)
  • Chromatin binding
    (GO:0003682)
  • Cochlea development
    (GO:0090102)
  • Commitment of neuronal cell to specific neuron type in forebrain
    (GO:0021902)
  • Cytoplasm
    (GO:0005737)
  • Definitive hemopoiesis
    (GO:0060216)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Embryonic placenta development
    (GO:0001892)
  • Eosinophil fate commitment
    (GO:0035854)
  • Fat cell differentiation
    (GO:0045444)
  • Gabaergic neuron differentiation
    (GO:0097154)
  • Glandular epithelial cell differentiation
    (GO:0002067)
  • Glandular epithelial cell maturation
    (GO:0002071)
  • Hematopoietic progenitor cell differentiation
    (GO:0002244)
  • Hematopoietic stem cell homeostasis
    (GO:0061484)
  • Homeostasis of number of cells within a tissue
    (GO:0048873)
  • Inner ear morphogenesis
    (GO:0042472)
  • Myeloid cell differentiation
    (GO:0030099)
  • Negative regulation of brown fat cell differentiation
    (GO:1903444)
  • Negative regulation of endothelial cell apoptotic process
    (GO:2000352)
  • Negative regulation of gene expression
    (GO:0010629)
  • Negative regulation of hematopoietic progenitor cell differentiation
    (GO:1901533)
  • Negative regulation of macrophage differentiation
    (GO:0045650)
  • Negative regulation of myeloid cell differentiation
    (GO:0045638)
  • Negative regulation of neural precursor cell proliferation
    (GO:2000178)
  • Negative regulation of neuroblast proliferation
    (GO:0007406)
  • Negative regulation of notch signaling pathway
    (GO:0045746)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Neural precursor cell proliferation
    (GO:0061351)
  • Neuroblast proliferation
    (GO:0007405)
  • Neuroendocrine cell differentiation
    (GO:0061101)
  • Neuron differentiation
    (GO:0030182)
  • Neuron fate commitment
    (GO:0048663)
  • Neuron maturation
    (GO:0042551)
  • Neuron migration
    (GO:0001764)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Phagocytosis
    (GO:0006909)
  • Pituitary gland development
    (GO:0021983)
  • Positive regulation of angiogenesis
    (GO:0045766)
  • Positive regulation of blood vessel endothelial cell migration
    (GO:0043536)
  • Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
    (GO:1903589)
  • Positive regulation of cell migration involved in sprouting angiogenesis
    (GO:0090050)
  • Positive regulation of cytosolic calcium ion concentration
    (GO:0007204)
  • Positive regulation of erythrocyte differentiation
    (GO:0045648)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of mast cell degranulation
    (GO:0043306)
  • Positive regulation of megakaryocyte differentiation
    (GO:0045654)
  • Positive regulation of mirna transcription
    (GO:1902895)
  • Positive regulation of neuron differentiation
    (GO:0045666)
  • Positive regulation of phagocytosis
    (GO:0050766)
  • Positive regulation of phagocytosis, engulfment
    (GO:0060100)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of forebrain neuron differentiation
    (GO:2000977)
  • Regulation of primitive erythrocyte differentiation
    (GO:0010725)
  • Response to lipid
    (GO:0033993)
  • Rna polymerase ii-specific dna-binding transcription factor binding
    (GO:0061629)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Semicircular canal development
    (GO:0060872)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Somatic stem cell population maintenance
    (GO:0035019)
  • Thyroid-stimulating hormone-secreting cell differentiation
    (GO:0060129)
  • Transcription by rna polymerase ii
    (GO:0006366)
  • Transcription coactivator binding
    (GO:0001223)
  • Transcription coregulator binding
    (GO:0001221)
  • Transcription regulator complex
    (GO:0005667)
  • Urogenital system development
    (GO:0001655)
  • Vascular wound healing
    (GO:0061042)
  • Ventral spinal cord interneuron differentiation
    (GO:0021514)
  • Zinc ion binding
    (GO:0008270)

Other Information

Genular Protein ID: 3330001827

Symbol: GATA2_RAT

Name: Endothelial transcription factor GATA-2

UniProtKB Accession Codes:

Q924Y4 Q8VHY4

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 CDD 1 CTD 1 EMBL 5 Ensembl 4 ExpressionAtlas 1 GO 81 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 2 RefSeq 3 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 2 eggNOG 1

Citations:

PubMed ID: 12933836

Title: Effect of transcription factor GATA-2 on phagocytic activity of alveolar macrophages from Pneumocystis carinii-infected hosts.

PubMed ID: 12933836

DOI: 10.1128/iai.71.9.4943-4952.2003

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 480
  • Mass: 50464
  • Checksum: 80FBA84AA4258EAD
  • Sequence:
    • MEVAPEQPRW MAHPAVLNAQ HPDSHHPGLA HNYMEPAQLL PPDEVDVFFN HLDSQGNPYY 
ANPAHARARV SYSPAHARLT GGQMCRPHLL HSPGLPWLDG GKAALSAAAA HHHSPWTVSP 
FSKTPLHPSA AGAPGGPLSV YPGAAGGSGG GSGSSVASLT PTAAHSGSHL FGFPPTPPKE 
VSPDPSTTGA ASPASPSAGG SVARGEDKDG VKYQVSLSES MKMEGGSPLR PGLAPMGTQP 
ATHHPIPTYP SYVPASAHEY GSGLFHPGGF LGGPASSFTP KQRSKARSCS EGRECVNCGA 
TATPLWRRDG TGHYLCNACG LYHKMNGQNR PLIKPKRRLS AARRAGTCCA NCQTTTTTLW 
RRNANGDPVC NACGLYYKLH NVNRPLTMKK EGIQTRNRKM SSKSKKSKKG AECFEELSKC 
MQEKSSPFSA AALAGHMAPV GHLPPFSHSG HILPTPTPIH PSSSLSFGHP HPSSMVTAMG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.