Genular: Defining Cellular Identity and Function

Details for: Htr2c

Gene ID: 25187

Symbol: Htr2c

Ensembl ID: ENSRNOG00000030877

Description: 5-hydroxytryptamine receptor 2C

Associated with

Amine ligand-binding receptors
(R-RNO-375280)
Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
G alpha (q) signalling events
(R-RNO-416476)
Gpcr downstream signalling
(R-RNO-388396)
Gpcr ligand binding
(R-RNO-500792)
Serotonin receptors
(R-RNO-390666)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
(GO:0071886)
Animal organ regeneration
(GO:0031100)
Behavioral fear response
(GO:0001662)
Behavioral response to nicotine
(GO:0035095)
Cell surface
(GO:0009986)
Cgmp-mediated signaling
(GO:0019934)
Chemical synaptic transmission
(GO:0007268)
Dendrite
(GO:0030425)
External side of plasma membrane
(GO:0009897)
Feeding behavior
(GO:0007631)
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
(GO:0007187)
G protein-coupled serotonin receptor activity
(GO:0004993)
G protein-coupled serotonin receptor complex
(GO:0098666)
G protein-coupled serotonin receptor signaling pathway
(GO:0098664)
Gq/11-coupled serotonin receptor activity
(GO:0001587)
Identical protein binding
(GO:0042802)
Intracellular calcium ion homeostasis
(GO:0006874)
Locomotory behavior
(GO:0007626)
Negative regulation of dopamine metabolic process
(GO:0045963)
Neurotransmitter receptor activity
(GO:0030594)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Phospholipase c-activating serotonin receptor signaling pathway
(GO:0007208)
Phospholipase d-activating g protein-coupled receptor signaling pathway
(GO:0031583)
Plasma membrane
(GO:0005886)
Positive regulation of acetylcholine secretion, neurotransmission
(GO:0014057)
Positive regulation of calcium-mediated signaling
(GO:0050850)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of fat cell differentiation
(GO:0045600)
Positive regulation of gamma-aminobutyric acid secretion
(GO:0014054)
Positive regulation of phosphatidylinositol biosynthetic process
(GO:0010513)
Positive regulation of vasoconstriction
(GO:0045907)
Protein binding
(GO:0005515)
Regulation of appetite
(GO:0032098)
Regulation of corticotropin-releasing hormone secretion
(GO:0043397)
Regulation of nervous system process
(GO:0031644)
Release of sequestered calcium ion into cytosol
(GO:0051209)
Response to xenobiotic stimulus
(GO:0009410)
Sensitization
(GO:0046960)
Serotonin binding
(GO:0051378)
Synapse
(GO:0045202)

Other Information

Proteins

5-hydroxytryptamine receptor 1C
Q62842_RAT

Genular Protein ID: 1735866985

Symbol: 5HT2C_RAT

Name: 5-hydroxytryptamine receptor 1C

UniProtKB Accession Codes:

P08909

Database IDs:

Citations:

PubMed ID: 3399891

Title: Molecular characterization of a functional cDNA encoding the serotonin 1c receptor.

PubMed ID: 3399891

DOI: 10.1126/science.3399891

PubMed ID: 12682077

Title: Agonist-induced phosphorylation of the serotonin 5-HT2C receptor regulates its interaction with multiple PDZ protein 1.

PubMed ID: 12682077

DOI: 10.1074/jbc.m210973200

Sequence Information:

Length: 460
Mass: 51917
Checksum: D44E977D8F80047E
Sequence:

MVNLGNAVRS LLMHLIGLLV WQFDISISPV AAIVTDTFNS SDGGRLFQFP DGVQNWPALS 
IVVIIIMTIG GNILVIMAVS MEKKLHNATN YFLMSLAIAD MLVGLLVMPL SLLAILYDYV 
WPLPRYLCPV WISLDVLFST ASIMHLCAIS LDRYVAIRNP IEHSRFNSRT KAIMKIAIVW 
AISIGVSVPI PVIGLRDESK VFVNNTTCVL NDPNFVLIGS FVAFFIPLTI MVITYFLTIY 
VLRRQTLMLL RGHTEEELAN MSLNFLNCCC KKNGGEEENA PNPNPDQKPR RKKKEKRPRG 
TMQAINNEKK ASKVLGIVFF VFLIMWCPFF ITNILSVLCG KACNQKLMEK LLNVFVWIGY 
VCSGINPLVY TLFNKIYRRA FSKYLRCDYK PDKKPPVRQI PRVAATALSG RELNVNIYRH 
TNERVARKAN DPEPGIEMQV ENLELPVNPS NVVSERISSV

Genular Protein ID: 1589444534

Symbol: Q62842_RAT

Name: N/A

UniProtKB Accession Codes:

Q62842

Database IDs:

Citations:

PubMed ID: 8863824

Title: Identification, molecular cloning, and distribution of a short variant of the 5-hydroxytryptamine2C receptor produced by alternative splicing.

PubMed ID: 8863824

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

Length: 294
Mass: 33653
Checksum: 6CC5803421AC1562
Sequence:

MCYFQLRPSC TSAPYRWTGV SVPIPVIGLR DESKVFVNNT TCVLNDPNFV LIGSFVAFFI 
PLTIMVITYF LTIYVLRRQT LMLLRGHTEE ELANMSLNFL NCCCKKNGGE EENAPNPNPD 
QKPRRKKKEK RPRGTMQAIN NEKKASKVLG IVFFVFLIMW CPFFITNILS VLCGKACNQK 
LMEKLLNVFV WIGYVCSGIN PLVYTLFNKI YRRAFSKYLR CDYKPDKKPP VRQIPRVAAT 
ALSGRELNVN IYRHTNERVA RKANDPEPGI EMQVENLELP VNPSNVVSER ISSV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Htr2c

Associated with

Other Information

Molecular characterization of a functional cDNA encoding the serotonin 1c receptor. PubMed ID: 3399891

Agonist-induced phosphorylation of the serotonin 5-HT2C receptor regulates its interaction with multiple PDZ protein 1. PubMed ID: 12682077

Identification, molecular cloning, and distribution of a short variant of the 5-hydroxytryptamine2C receptor produced by alternative splicing. PubMed ID: 8863824

Gene and alternative splicing annotation with AIR. PubMed ID: 15632090

Database document:

PubMed ID: 3399891

PubMed ID: 12682077

PubMed ID: 8863824

PubMed ID: 15632090