Pcsk1 | ENSRNOG00000011107 | NCBI 25204

Details for: Pcsk1

Gene ID: 25204

Symbol: Pcsk1

Ensembl ID: ENSRNOG00000011107

Description: proprotein convertase subtilisin/kexin type 1

Associated with

Metabolism of proteins
(R-RNO-392499)
Peptide hormone biosynthesis
(R-RNO-209952)
Peptide hormone metabolism
(R-RNO-2980736)
Synthesis, secretion, and deacylation of ghrelin
(R-RNO-422085)
Axon terminus
(GO:0043679)
Dendrite
(GO:0030425)
Endopeptidase activity
(GO:0004175)
Extracellular space
(GO:0005615)
Identical protein binding
(GO:0042802)
Insulin processing
(GO:0030070)
Membrane
(GO:0016020)
Neurogenesis
(GO:0022008)
Neuronal cell body
(GO:0043025)
Neuron projection
(GO:0043005)
Pancreas development
(GO:0031016)
Peptide biosynthetic process
(GO:0043043)
Peptide hormone processing
(GO:0016486)
Perikaryon
(GO:0043204)
Perinuclear region of cytoplasm
(GO:0048471)
Pituitary gland development
(GO:0021983)
Positive regulation of protein secretion
(GO:0050714)
Protein autoprocessing
(GO:0016540)
Protein processing
(GO:0016485)
Response to axon injury
(GO:0048678)
Response to calcium ion
(GO:0051592)
Response to chlorate
(GO:0010157)
Response to fatty acid
(GO:0070542)
Response to glucocorticoid
(GO:0051384)
Response to glucose
(GO:0009749)
Response to inorganic substance
(GO:0010035)
Response to interleukin-1
(GO:0070555)
Response to lipopolysaccharide
(GO:0032496)
Response to nutrient levels
(GO:0031667)
Response to organic cyclic compound
(GO:0014070)
Response to peptide hormone
(GO:0043434)
Response to xenobiotic stimulus
(GO:0009410)
Secretory granule
(GO:0030141)
Secretory granule lumen
(GO:0034774)
Serine-type endopeptidase activity
(GO:0004252)
Trans-golgi network
(GO:0005802)
Transport vesicle
(GO:0030133)

Other Information

Proteins

Neuroendocrine convertase 1

Genular Protein ID: 2733989475

Symbol: NEC1_RAT

Name: Neuroendocrine convertase 1

UniProtKB Accession Codes:

P28840

Database IDs:

Citations:

PubMed ID: 1791845

Title: Prohormone-converting enzymes: regulation and evaluation of function using antisense RNA.

PubMed ID: 1791845

DOI: 10.1210/mend-5-12-2014

PubMed ID: 1954888

Title: Isolation of two complementary deoxyribonucleic acid clones from a rat insulinoma cell line based on similarities to Kex2 and furin sequences and the specific localization of each transcript to endocrine and neuroendocrine tissues in rats.

PubMed ID: 1954888

DOI: 10.1210/endo-129-6-3053

Sequence Information:

Length: 752
Mass: 84121
Checksum: F630AD830A076DED
Sequence:

MKQRGWTLQC TAFTLFCVWC ALNSVKAKRQ FVNEWAAEIH GGPEAASAIA EELGYDLLGQ 
IGSLENHYLF KHKNHPRRSR RSALHITKRL SDDDRVIWAE QQYEKERRKR SVPRDSALNL 
FNDPMWNQQW YLQDTRMTAS LPKLDLHVIP VWQKGITGKG VVITVLDDGL EWNHTDIYAN 
YDPEASYDFN DNDHDPFPRY DPTNENKHGT RCAGEIAMQA NNHKCGVGVA YNSKVGGIRM 
LDGIVTDAIE ASSIGFNPGH VDIYSASWGP NDDGKTVEGP GRLAQKAFEY GVKQGRQGKG 
SIFVWASGNG GRQGDNCDCD GYTDSIYTIS ISSASQQGLS PWYAEKCSST LATSYSSGDY 
TDQRITSADL HNDCTETHTG TSASAPLAAG IFALALEANP NLTWRDMQHL VVWTSEYDPL 
ANNPGWKKNG AGLMVNSRFG FGLLNAKALV DLADPRTWRN VPEKKECIIK DNNFEPRALK 
ANGEVIVEIP TRACEGQENA INSLEHVQFE ATIEYSRRGD LHVTLTSAAG TSTVLLAERE 
RDTSPNGFKN WDFMSVHTWG ENPVGTWTLK VTDMSGRMQN EGRIVNWKLI LHGTSSQPEH 
MKQPRVYTSY NTVQNDRRGV EKMVNVVEEK PTQNSLNGNL LVPKNSSSSS VEDRRDEQVQ 
GAPSKAMLRL LQSAFSKNTP SKQSSKIPSA KLSVPYEGLY EALEKLNKPS QLEDSEDSLY 
SDYVDVFYNT KPYKHRDDRL LQALMDILNE KN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.