Akt2 | ENSRNOG00000018677 | NCBI 25233

Details for: Akt2

Gene ID: 25233

Symbol: Akt2

Ensembl ID: ENSRNOG00000018677

Description: AKT serine/threonine kinase 2

Associated with

Atp binding
(GO:0005524)
Carbohydrate transport
(GO:0008643)
Cell cortex
(GO:0005938)
Cellular response to high light intensity
(GO:0071486)
Cellular response to hormone stimulus
(GO:0032870)
Cellular response to insulin stimulus
(GO:0032869)
Cellular response to organic cyclic compound
(GO:0071407)
Cytosol
(GO:0005829)
Early endosome
(GO:0005769)
Glucose metabolic process
(GO:0006006)
Glycogen biosynthetic process
(GO:0005978)
Insulin-responsive compartment
(GO:0032593)
Insulin receptor signaling pathway
(GO:0008286)
Intracellular membrane-bounded organelle
(GO:0043231)
Intracellular signal transduction
(GO:0035556)
Metal ion binding
(GO:0046872)
Molecular function activator activity
(GO:0140677)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of long-chain fatty acid import across plasma membrane
(GO:0010748)
Negative regulation of rna splicing
(GO:0033119)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Peptidyl-serine phosphorylation
(GO:0018105)
Peripheral nervous system myelin maintenance
(GO:0032287)
Phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0043491)
Phosphorylation
(GO:0016310)
Plasma membrane
(GO:0005886)
Positive regulation of adipose tissue development
(GO:1904179)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell motility
(GO:2000147)
Positive regulation of fatty acid beta-oxidation
(GO:0032000)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of glucose import
(GO:0046326)
Positive regulation of glucose metabolic process
(GO:0010907)
Positive regulation of glycogen biosynthetic process
(GO:0045725)
Positive regulation of nitric oxide biosynthetic process
(GO:0045429)
Positive regulation of peptidyl-serine phosphorylation
(GO:0033138)
Positive regulation of positive chemotaxis
(GO:0050927)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of protein targeting to membrane
(GO:0090314)
Positive regulation of signal transduction
(GO:0009967)
Positive regulation of sodium ion transport
(GO:0010765)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein kinase c binding
(GO:0005080)
Protein localization to nucleus
(GO:0034504)
Protein localization to plasma membrane
(GO:0072659)
Protein serine/threonine kinase activity
(GO:0004674)
Protein serine kinase activity
(GO:0106310)
Regulation of translation
(GO:0006417)
Response to hypoxia
(GO:0001666)
Response to insulin
(GO:0032868)
Response to muscle activity
(GO:0014850)
Response to nutrient levels
(GO:0031667)
Retinal rod cell apoptotic process
(GO:0097473)
Ruffle membrane
(GO:0032587)
Sarcoplasmic reticulum
(GO:0016529)
Vesicle
(GO:0031982)

Other Information

Proteins

RAC-beta serine/threonine-protein kinase
Q3HSE5_RAT

Genular Protein ID: 1287226390

Symbol: AKT2_RAT

Name: RAC-beta serine/threonine-protein kinase

UniProtKB Accession Codes:

P47197

Database IDs:

Citations:

PubMed ID: 7999118

Title: Molecular cloning of rat RAC protein kinase alpha and beta and their association with protein kinase C zeta.

PubMed ID: 7999118

DOI: 10.1006/bbrc.1994.2738

PubMed ID: 20074525

Title: Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis.

PubMed ID: 20074525

DOI: 10.1016/j.cmet.2009.11.006

PubMed ID: 21620960

Title: Akt signalling in health and disease.

PubMed ID: 21620960

DOI: 10.1016/j.cellsig.2011.05.004

PubMed ID: 21432781

Title: Akt1 and Akt2: differentiating the aktion.

PubMed ID: 21432781

DOI: 10.14670/hh-26.651

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 481
Mass: 55543
Checksum: 3C4BE65B2F376F85
Sequence:

MNEVSVIKEG WLHKRGEYIK TWRPRYFLLK SDGSFIGYKE RPEAPDQTLP PLNNFSVAEC 
QLMKTERPRP NTFVIRCLQW TTVIERTFHV DSPDEREEWI RAIQMVANSL KQRGPGEDAM 
DYKCGSPSDS STSEMMEVAV SKARAKVTMN DFDYLKLLGK GTFGKVILVR EKATGRYYAM 
KILRKEVIIA KDEVAHTVTE SRVLQNTRHP FLTALKYAFQ THDRLCFVME YANGGDLFFH 
LSRERVFTED RARFYGAEIV SALEYLHSTD VVYRDIKLEN LMLDKDGHIK ITDFGLSKEG 
ISDGATMKTF CGTPEYLAPE VLEDNDYGRA VDWWGLGVVM YEMMCGRLPF YNQDHERLFE 
LILMEEIRFP RTLGPEAKSL LAGLLKKDPK QRLGGGPSDA KEVMEHRFFL SINWQDVVQK 
KLLPPFKPQV TSEVDTRYFD DEFTAQSITI TPPDRYDSLG SLELDQRTHF PQFSYSASIR 
E

Genular Protein ID: 3991608152

Symbol: Q3HSE5_RAT

Name: N/A

UniProtKB Accession Codes:

Q3HSE5

Database IDs:

Citations:

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

PubMed ID: 16452480

Title: Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation.

PubMed ID: 16452480

DOI: 10.1074/jbc.M510724200

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

Sequence Information:

Length: 481
Mass: 55629
Checksum: 4738A48046FE8714
Sequence:

MNEVSVIKEG WLHKRGEYIK TWRPRYFLLK SDGSFIGYKE RPEAPDQTLP PLNNFSVAEC 
QLMKTERPRP NTFVIRCLQW TTVIERTFHV DSPDEREEWI RAIQMVANSL KQRGPGEDAM 
DYKCGSPSDS STSEMMEVAV SKARAKVTMN DFDYLKLLGK GTFGKVILVR EKATGRYYAM 
KILRKEVIIA KDEVAHTVTE SRVLQNTRHP FLTALKYAFQ THDRLCFVME YANGGELFFH 
LSRERVFTED RARFYGAEIV SALEYLHSRD VVYRDIKLEN LMLDKDGHIK ITDFGLCKEG 
ISDGATMKTF CGTPEYLAPE VLEDNDYGRA VDWWGLGVVM YEMMCGRLPF YNQDHERLFE 
LILMEEIRFP RTLGPEAKSL LAGLLKKDPK QRLGGGPSDA KEVMEHRFFL SINWQDVVQK 
KLLPPFKPQV TSEVDTRYFD DEFTAQSITI TPPDRYDSLG SLELDQRTHF PQFSYSASIR 
E

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Akt2

Associated with

Other Information

Molecular cloning of rat RAC protein kinase alpha and beta and their association with protein kinase C zeta. PubMed ID: 7999118

Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis. PubMed ID: 20074525

Akt signalling in health and disease. PubMed ID: 21620960

Akt1 and Akt2: differentiating the aktion. PubMed ID: 21432781

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

Gene and alternative splicing annotation with AIR. PubMed ID: 15632090

Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane. Role of TRB3 in inhibition of Akt/protein kinase B activation. PubMed ID: 16452480

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

Database document:

PubMed ID: 7999118

PubMed ID: 20074525

PubMed ID: 21620960

PubMed ID: 21432781

PubMed ID: 22673903

PubMed ID: 15632090

PubMed ID: 16452480

PubMed ID: 22673903