Gpc3 | ENSRNOG00000060179 | NCBI 25236

Details for: Gpc3

Gene ID: 25236

Symbol: Gpc3

Ensembl ID: ENSRNOG00000060179

Description: glypican 3

Associated with

A tetrasaccharide linker sequence is required for gag synthesis
(R-RNO-1971475)
Chondroitin sulfate/dermatan sulfate metabolism
(R-RNO-1793185)
Glycosaminoglycan metabolism
(R-RNO-1630316)
Heparan sulfate/heparin (hs-gag) metabolism
(R-RNO-1638091)
Hs-gag biosynthesis
(R-RNO-2022928)
Hs-gag degradation
(R-RNO-2024096)
Metabolism
(R-RNO-1430728)
Metabolism of carbohydrates
(R-RNO-71387)
Metabolism of fat-soluble vitamins
(R-RNO-6806667)
Metabolism of proteins
(R-RNO-392499)
Metabolism of vitamins and cofactors
(R-RNO-196854)
Post-translational protein modification
(R-RNO-597592)
Post-translational protein phosphorylation
(R-RNO-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-RNO-381426)
Retinoid metabolism and transport
(R-RNO-975634)
Sensory perception
(R-RNO-9709957)
Visual phototransduction
(R-RNO-2187338)
Animal organ morphogenesis
(GO:0009887)
Anterior/posterior axis specification
(GO:0009948)
Biological_process
(GO:0008150)
Body morphogenesis
(GO:0010171)
Bone mineralization
(GO:0030282)
Branching involved in ureteric bud morphogenesis
(GO:0001658)
Canonical wnt signaling pathway
(GO:0060070)
Cell migration
(GO:0016477)
Cell migration involved in gastrulation
(GO:0042074)
Cell proliferation involved in kidney development
(GO:0072111)
Cell proliferation involved in metanephros development
(GO:0072203)
Cell surface
(GO:0009986)
Collagen-containing extracellular matrix
(GO:0062023)
Coronary vasculature development
(GO:0060976)
Embryonic hindlimb morphogenesis
(GO:0035116)
Epithelial cell proliferation
(GO:0050673)
Kidney development
(GO:0001822)
Lung development
(GO:0030324)
Lysosome
(GO:0005764)
Mesenchymal cell proliferation involved in ureteric bud development
(GO:0072138)
Mesonephric duct morphogenesis
(GO:0072180)
Negative regulation of canonical wnt signaling pathway
(GO:0090090)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of epithelial cell proliferation
(GO:0050680)
Negative regulation of growth
(GO:0045926)
Negative regulation of smoothened signaling pathway
(GO:0045879)
Osteoclast differentiation
(GO:0030316)
Peptidyl-dipeptidase inhibitor activity
(GO:0060422)
Plasma membrane
(GO:0005886)
Positive regulation of bmp signaling pathway
(GO:0030513)
Positive regulation of canonical wnt signaling pathway
(GO:0090263)
Positive regulation of endocytosis
(GO:0045807)
Positive regulation of glucose import
(GO:0046326)
Positive regulation of protein catabolic process
(GO:0045732)
Positive regulation of smoothened signaling pathway
(GO:0045880)
Positive regulation of wnt signaling pathway, planar cell polarity pathway
(GO:2000096)
Regulation of canonical wnt signaling pathway
(GO:0060828)
Regulation of growth
(GO:0040008)
Regulation of non-canonical wnt signaling pathway
(GO:2000050)
Regulation of protein localization to membrane
(GO:1905475)
Response to bacterium
(GO:0009617)
Side of membrane
(GO:0098552)
Smoothened signaling pathway
(GO:0007224)
Wnt signaling pathway, planar cell polarity pathway
(GO:0060071)

Other Information

Proteins

Glypican-3

Genular Protein ID: 1638114904

Symbol: GPC3_RAT

Name: Glypican-3

UniProtKB Accession Codes:

P13265 Q5U326

Database IDs:

Citations:

PubMed ID: 3185547

Title: Isolation of a cDNA corresponding to a developmentally regulated transcript in rat intestine.

PubMed ID: 3185547

DOI: 10.1128/mcb.8.10.4243-4249.1988

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7487896

Title: Identification of a new membrane-bound heparan sulphate proteoglycan.

PubMed ID: 7487896

DOI: 10.1042/bj3110561

PubMed ID: 9065409

Title: OCI-5/rat glypican-3 binds to fibroblast growth factor-2 but not to insulin-like growth factor-2.

PubMed ID: 9065409

DOI: 10.1074/jbc.272.12.7574

Sequence Information:

Length: 597
Mass: 67049
Checksum: C556AD4127685687
Sequence:

MAGTVRTACL LVAMLLGLGC LGQAQPPPPP DATCHQVRSF FQRLQPGLKW VPETPVPGSD 
LQVCLPKGPT CCSRKMEEKY QLTARLNMEQ LLQSASMELK FLIIQNAAVF QEAFEIVVRH 
AKNYTNAMFK NNYPSLTPQA FEFVGEFFTD VSLYILGSDI NVDDMVNELF DSLFPVIYTQ 
MMNPGLPESV LDINECLRGA RRDLKVFGSF PKLIMTQVSK SLQVTRIFLQ ALNLGIEVIN 
TTDHLKFSKD CGRMLTRMWY CSYCQGLMMV KPCGGYCNVV MQGCMAGVVE IDKYWREYIL 
SLEELVNGMY RIYDMENVLL GLFSTIHDSI QYVQKNGGKL TTTIGKLCAH SQQRQYRSAY 
YPEDLFIDKK VLKVARVEHE ETLSSRRREL IQKLKSFISF YSALPGYICS HSPVAENDTL 
CWNGQELVER YSQKAARNGM KNQFNLHELK MKGPEPVVSQ IIDKLKHINQ LLRTMSVPKG 
KVVDKSLDEE GLESGDCGDD EDECIGSSGD GMMKVKNQLR FLAELAYDLD VDDAPGNKQH 
GNQKDNEITT SHSVGNMPSP LKILISVAIY VACFFSWCTD LPCPCLCCPA APCGPPT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Gpc3

Associated with

Other Information

Isolation of a cDNA corresponding to a developmentally regulated transcript in rat intestine. PubMed ID: 3185547

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of a new membrane-bound heparan sulphate proteoglycan. PubMed ID: 7487896

OCI-5/rat glypican-3 binds to fibroblast growth factor-2 but not to insulin-like growth factor-2. PubMed ID: 9065409

Database document:

PubMed ID: 3185547

PubMed ID: 15489334

PubMed ID: 7487896

PubMed ID: 9065409