Details for: Bckdha

Gene ID: 25244

Symbol: Bckdha

Ensembl ID: ENSRNOG00000020607

Description: branched chain keto acid dehydrogenase E1 subunit alpha

Associated with

  • Branched-chain amino acid catabolism
    (R-RNO-70895)
  • Glyoxylate metabolism and glycine degradation
    (R-RNO-389661)
  • Metabolism
    (R-RNO-1430728)
  • Metabolism of amino acids and derivatives
    (R-RNO-71291)
  • 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity
    (GO:0003863)
  • Branched-chain alpha-keto acid dehydrogenase activity
    (GO:0047101)
  • Branched-chain amino acid catabolic process
    (GO:0009083)
  • Metal ion binding
    (GO:0046872)
  • Mitochondrial alpha-ketoglutarate dehydrogenase complex
    (GO:0005947)
  • Oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
    (GO:0016624)
  • Protein-containing complex binding
    (GO:0044877)
  • Response to camp
    (GO:0051591)
  • Response to glucocorticoid
    (GO:0051384)
  • Response to nutrient
    (GO:0007584)

Other Information

Genular Protein ID: 1708681260

Symbol: ODBA_RAT

Name: Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain

UniProtKB Accession Codes:

P11960

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID 1 CDD 1 CTD 1 ChEBI 21 EC 1 EMBL 1 GO 9 Gene3D 1 GlyGen 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MINT 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 2 Reactome 2 RefSeq 1 Rhea 4 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 UniProtKB 2 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 2822716

Title: Molecular cloning of a cDNA for the E1 alpha subunit of rat liver branched chain alpha-ketoacid dehydrogenase.

PubMed ID: 2822716

DOI: 10.1016/s0021-9258(18)48161-6

PubMed ID: 16396499

Title: Phosphoproteomic analysis of rat liver by high capacity IMAC and LC-MS/MS.

PubMed ID: 16396499

DOI: 10.1021/pr0503073

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 29779826

Title: The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase.

PubMed ID: 29779826

DOI: 10.1016/j.cmet.2018.04.015

Sequence Information:

  • Length: 441
  • Mass: 50164
  • Checksum: FFD7709A94094C8E
  • Sequence:
    • SAAKIWRPSR GLRQAALLLL GRPGARGLAR FHPSRQQQQQ FPSLDDKPQF PGASAEFVDK 
LEFIQPNVIS GIPIYRVMDR QGQIINPSED PHLPQEEVLK LYRSMTLLNT MDRILYESQR 
QGRISFYMTN YGEEGTHVGS AAALERTDLV FGQYREAGVL MYRDYPLELF MAQCYGNVSD 
PGKGRQMPVH YGCKERHFVT ISSPLATQIP QAVGAAYAAK RANANQIVIC YFGEGAASEG 
DAHAGFNFAA TLECPIIFFC RNNGYAISTP TSEQYRGDGI AARGPGYGIM SIRVDGNDVF 
AVYNATKEAR RRAVAENQPF LIEAMTYRIG HHSTSDDSSA YRSVDEVNYW DKQDHPISRL 
RQYLLNQGWW DEEQEKAWRK QSRKKVMEAF EQAERKLKPN PSLLFSDVYQ EMPAQLRRQQ 
ESLARHLQTY GEHYPLDHFD K

Genular Protein ID: 3567508316

Symbol: B1WBN3_RAT

Name: N/A

UniProtKB Accession Codes:

B1WBN3

Database IDs:

ARBA 6 AlphaFoldDB 1 CDD 1 CTD 1 ChEBI 6 EC 1 EMBL 2 GO 1 Gene3D 1 HOGENOM 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 RGD 2 RefSeq 1 Rhea 4 RuleBase 1 SUPFAM 1 TreeFam 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 446
  • Mass: 50668
  • Checksum: 621A9EA4405776F3
  • Sequence:
    • MAVAMSAAKI WRPSRGLRQA ALLLLGRPGA RGLARFHPSR QQQQQFPSLD DKPQFPGASA 
EFVDKLEFIQ PNVISGIPIY RVMDRQGQII NPSEDPHLPQ EEVLKLYRSM TLLNTMDRIL 
YESQRQGRIS FYMTNYGEEG THVGSAAALE RTDLVFGQYR EAGVLMYRDY PLELFMAQCY 
GNVSDPGKGR QMPVHYGCKE RHFVTISSPL ATQIPQAVGA AYAAKRANAN QIVICYFGEG 
AASEGDAHAG FNFAATLECP IIFFCRNNGY AISTPTSEQY RGDGIAARGP GYGIMSIRVD 
GNDVFAVYNA TKEARRRAVA ENQPFLIEAM TYRIGHHSTS DDSSAYRSVD EVNYWDKQDH 
PISRLRQYLL NQGWWDEEQE KAWRKQSRKK VMEAFEQAER KLKPNPSLLF SDVYQEMPAQ 
LRRQQESLAR HLQTYGEHYP LDHFDK

Genular Protein ID: 1942530853

Symbol: Q5EB89_RAT

Name: N/A

UniProtKB Accession Codes:

Q5EB89

Database IDs:

ARBA 6 AlphaFoldDB 1 CDD 1 CTD 1 ChEBI 6 EC 1 EMBL 2 GO 1 Gene3D 1 Genevisible 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 2 RGD 2 RefSeq 1 Rhea 4 RuleBase 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 328
  • Mass: 37335
  • Checksum: 730000C6D922B557
  • Sequence:
    • ILYESQRQGR ISFYMTNYGE EGTHVGSAAA LERTDLVFGQ YREAGVLMYR DYPLELFMAQ 
CYGNVSDPGK GRQMPVHYGC KERHFVTISS PLATQIPQAV GAAYAAKRAN ANQIVICYFG 
EGAASEGDAH AGFNFAATLE CPIIFFCRNN GYAISTPTSE QYRGDGIAAR GPGYGIMSIR 
VDGNDVFAVY NATKEARRRA VAENQPFLIE AMTYRIGHHS TSDDSSAYRS VDEVNYWDKQ 
DHPISRLRQY LLNQGWWDEE QEKAWRKQSR KKVMEAFEQA ERKLKPNPSL LFSDVYQEMP 
AQLRRQQESL ARHLQTYGEH YPLDHFDK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.