Pdgfra | ENSRNOG00000002244 | NCBI 25267

Details for: Pdgfra

Gene ID: 25267

Symbol: Pdgfra

Ensembl ID: ENSRNOG00000002244

Description: platelet derived growth factor receptor alpha

Associated with

Downstream signal transduction
(R-RNO-186763)
Intracellular signaling by second messengers
(R-RNO-9006925)
Mapk1/mapk3 signaling
(R-RNO-5684996)
Mapk family signaling cascades
(R-RNO-5683057)
Negative regulation of the pi3k/akt network
(R-RNO-199418)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-RNO-6811558)
Pip3 activates akt signaling
(R-RNO-1257604)
Raf/map kinase cascade
(R-RNO-5673001)
Signaling by pdgf
(R-RNO-186797)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signal transduction
(R-RNO-162582)
Adrenal gland development
(GO:0030325)
Anatomical structure morphogenesis
(GO:0009653)
Animal organ morphogenesis
(GO:0009887)
Atp binding
(GO:0005524)
Cardiac myofibril assembly
(GO:0055003)
Cell chemotaxis
(GO:0060326)
Cell junction
(GO:0030054)
Cell migration
(GO:0016477)
Cell surface
(GO:0009986)
Cellular response to amino acid stimulus
(GO:0071230)
Cellular response to fibroblast growth factor stimulus
(GO:0044344)
Cellular response to growth factor stimulus
(GO:0071363)
Cellular response to interleukin-1
(GO:0071347)
Cellular response to reactive oxygen species
(GO:0034614)
Cilium
(GO:0005929)
Cytoplasm
(GO:0005737)
Embryonic cranial skeleton morphogenesis
(GO:0048701)
Embryonic digestive tract morphogenesis
(GO:0048557)
Embryonic skeletal system morphogenesis
(GO:0048704)
Estrogen metabolic process
(GO:0008210)
External side of plasma membrane
(GO:0009897)
Extracellular matrix organization
(GO:0030198)
Face morphogenesis
(GO:0060325)
Female gonad development
(GO:0008585)
Golgi apparatus
(GO:0005794)
Hematopoietic progenitor cell differentiation
(GO:0002244)
Inner ear development
(GO:0048839)
In utero embryonic development
(GO:0001701)
Leydig cell differentiation
(GO:0033327)
Lung development
(GO:0030324)
Lung growth
(GO:0060437)
Luteinization
(GO:0001553)
Male genitalia development
(GO:0030539)
Male gonad development
(GO:0008584)
Metal ion binding
(GO:0046872)
Metanephric glomerular capillary formation
(GO:0072277)
Microvillus
(GO:0005902)
Multicellular organism development
(GO:0007275)
Negative regulation of platelet activation
(GO:0010544)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Odontogenesis of dentin-containing tooth
(GO:0042475)
Phosphatidylinositol 3-kinase binding
(GO:0043548)
Phosphorylation
(GO:0016310)
Plasma membrane
(GO:0005886)
Platelet-derived growth factor alpha-receptor activity
(GO:0005018)
Platelet-derived growth factor binding
(GO:0048407)
Platelet-derived growth factor receptor-alpha signaling pathway
(GO:0035790)
Platelet-derived growth factor receptor binding
(GO:0005161)
Platelet-derived growth factor receptor signaling pathway
(GO:0048008)
Platelet aggregation
(GO:0070527)
Positive regulation of branching involved in lung morphogenesis
(GO:0061047)
Positive regulation of calcium-mediated signaling
(GO:0050850)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cell proliferation by vegf-activated platelet derived growth factor receptor signaling pathway
(GO:0038091)
Positive regulation of chemotaxis
(GO:0050921)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of fibroblast proliferation
(GO:0048146)
Positive regulation of kinase activity
(GO:0033674)
Positive regulation of peptidyl-tyrosine phosphorylation
(GO:0050731)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Protein-containing complex binding
(GO:0044877)
Protein homodimerization activity
(GO:0042803)
Protein kinase activity
(GO:0004672)
Regulation of mesenchymal stem cell differentiation
(GO:2000739)
Response to cytokine
(GO:0034097)
Response to estradiol
(GO:0032355)
Response to estrogen
(GO:0043627)
Response to formaldehyde
(GO:1904404)
Response to hormone
(GO:0009725)
Response to hyperoxia
(GO:0055093)
Response to inorganic substance
(GO:0010035)
Response to organic substance
(GO:0010033)
Retina vasculature development in camera-type eye
(GO:0061298)
Roof of mouth development
(GO:0060021)
Signal transduction involved in regulation of gene expression
(GO:0023019)
Skeletal system morphogenesis
(GO:0048705)
Transmembrane receptor protein tyrosine kinase activity
(GO:0004714)
Transmembrane receptor protein tyrosine kinase signaling pathway
(GO:0007169)
Vascular endothelial growth factor binding
(GO:0038085)
Vascular endothelial growth factor receptor activity
(GO:0005021)
White fat cell differentiation
(GO:0050872)
Wound healing
(GO:0042060)

Other Information

Proteins

Platelet-derived growth factor receptor alpha
A6JD04_RAT

Genular Protein ID: 3820587183

Symbol: PGFRA_RAT

Name: Platelet-derived growth factor receptor alpha

UniProtKB Accession Codes:

P20786

Database IDs:

Citations:

PubMed ID: 2157969

Title: Isolation and characterization of the alpha platelet-derived growth factor receptor from rat olfactory epithelium.

PubMed ID: 2157969

DOI: 10.1128/mcb.10.5.2237-2246.1990

PubMed ID: 8318539

Title: Conservation in sequence and affinity of human and rodent PDGF ligands and receptors.

PubMed ID: 8318539

DOI: 10.1016/0167-4781(93)90127-y

Sequence Information:

Length: 1088
Mass: 122642
Checksum: 590C8BB0418801E7
Sequence:

MGTSQAFLVL SCLLTGPSLI VCQLLLPSIL PNENEKIVPL SSSFSLRCFG ESEVSWQHPM 
SEEEDPNVEI RTEENNSSLF VTVLEVVNAS AAHTGWYTCY YNHTQTEESE IEGRHIYIYV 
PDPDMAFVPL GMTDSLVIVE EDDSAIIPCL TTDPDTEVTL HNNGRLVPAS YDSRQGFNGT 
FSVGPYICEA TVRGRTFKTS EFNVYALKAT SELNLEMDTR QTVYKAGETI VVTCAVFNNE 
VVDLQWTYPG EVRNKGITML EEIKLPSIKL VYTLTVPKAT VKDSGDYECA ARQATKEVKE 
MKTVTISVHE KGFVQIRPTF GHLETVNLHQ VREFVVEVQA YPTPRISWLK DNLTLIENLT 
EITTDVQRSQ ETRYQSKLKL IRAKEEDSGH YTIIVQNDDD MKSYTFELST LVPASILELV 
DDHHGSGGGQ TVRCTAEGTP LPNIEWMICK DIKKCNNDTS WTVLASNVSN IITEFHQRGR 
STVEGRVSFA KVEETIAVRC LAKNDLGIGN RELKLVAPSL RSELTVAAAV LVLLVIVIVS 
LIVLVVIWKQ KPRYEIRWRV IESISPDGHE YIYVDPMQLP YDSRWEFPRD GLVLGRILGS 
GAFGKVVEGT AYGLSRSQPV MKVAVKMLKP TARSSEKQAL MSELKIMTHL GPHLNIVNLL 
GACTKSGPIY IITEYCFYGD LVNYLHKNRD SFMSRHPEKP KKDLDIFGLN PADESTRSYV 
ILSFENNGDY VDMKQADTTQ YVPMLERKEV SKYSDIQRSL YDRPASYKKK SMLDSEAKNL 
LSDDDSEGLT LLDLLSFTYQ VARGMEFLAS KNCVHRDLAA RNVLLAQGKI VKICDFGLAR 
DIMHDSNYVS KGSTFLPVKW MAPESIFDNL YTTLSDVWSY GVLLWEIFSL GGTPYPGMMV 
DSTFYNKIKS GYRMAKPDHA TSEVYEIMVQ CWNSEPEKRP SFYHLSEIVE NLLPGQYKKS 
YEKIHLDFLK SDHPAVARMR VDSDNAYIGV TYKNEEDKLK EWEGGLDEQR LSADSGYIIP 
LPDIDPVPEE EDLGKRNRHS SQTSEESAIE TGSSSSTFIK REDETIEDID MMDDIGIDSS 
DLVEDSFL

Genular Protein ID: 2572627466

Symbol: A6JD04_RAT

Name: N/A

UniProtKB Accession Codes:

A6JD04

Database IDs:

Citations:

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

Length: 1088
Mass: 122699
Checksum: 749725FA4961DB23
Sequence:

MGTSQAFLVL SCLLTGPSLI VCQLLLPSIL PNENEKIVPL SSSFSLRCFG ESEVSWQHPM 
SEEEDPNVEI RTEENNSSLF VTVLEVVNAS AAHTGWYTCY YNHTQTEESE IEGRHIYIYV 
PDPDMAFVPL GMTDSLVIVE EDDSAIIPCR TTDPDTEVTL HNNGRLVPAS YDSRQGFNGT 
FSVGPYICEA TVRGRTFKTS EFNVYALKAT SELNLEMDTR QTVYKAGETI VVTCAVFNNE 
VVDLQWTYPG EVRNKGITML EEIKLPSIKL VYTLTVPKAT VKDSGDYECA ARQATKEVKE 
MKTVTISVHE KGFVQIRPTF GHLETVNLHQ VREFVVEVQA YPTPRISWLK DNLTLIENLT 
EITTDVQRSQ ETRYQSKLKL IRAKEEDSGH YTIIVQNDDD MKSYTFELST LVPASILELV 
DDHHGSGGGQ TVRCTAEGTP LPNIEWMICK DIKKCNNDTS WTVLASNVSN IITEFHQRGR 
STVEGRVSFA KVEETIAVRC LAKNDLGIGN RELKLVAPTL RSELTVAAAV LVLLVIVIVS 
LIVLVVIWKQ KPRYEIRWRV IESISPDGHE YIYVDPMQLP YDSRWEFPRD GLVLGRILGS 
GAFGKVVEGT AYGLSRSQPV MKVAVKMLKP TARSSEKQAL MSELKIMTHL GPHLNIVNLL 
GACTKSGPIY IITEYCFYGD LVNYLHKNRD SFMSRHPEKP KKDLDIFGLN PADESTRSYV 
ILSFENNGDY VDMKQADTTQ YVPMLERKEV SKYSDIQRSL YDRPASYKKK SMLDSEAKNL 
LSDDDSEGLT LLDLLSFTYQ VARGMEFLAS KNCVHRDLAA RNVLLAQGKI VKICDFGLAR 
DIMHDSNYVS KGSTFLPVKW MAPESIFDNL YTTLSDVWSY GVLLWEIFSL GGTPYPGMMV 
DSTFYNKIKS GYRMAKPDHA TSEVYEIMVQ CWNSEPEKRP SFYHLSEIVE NLLPGQYKKS 
YEKIHLDFLK SDHPAVARMR VDSDNAYIGV TYKNEEDKLK EWEGGLDEQR LSADSGYIIP 
LPDIDPVPEE EDLGKRNRHS SQTSEESAIE TGSSSSTFIK REDETIEDID MMDDIGIDSS 
DLVEDSFL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.