Mapk10 | ENSRNOG00000002079 | NCBI 25272

Details for: Mapk10

Gene ID: 25272

Symbol: Mapk10

Ensembl ID: ENSRNOG00000002079

Description: mitogen activated protein kinase 10

Associated with

Activation of the ap-1 family of transcription factors
(R-RNO-450341)
Cellular responses to stimuli
(R-RNO-8953897)
Cellular responses to stress
(R-RNO-2262752)
Cellular senescence
(R-RNO-2559583)
Cytokine signaling in immune system
(R-RNO-1280215)
Fc epsilon receptor (fceri) signaling
(R-RNO-2454202)
Fceri mediated mapk activation
(R-RNO-2871796)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Interleukin-17 signaling
(R-RNO-448424)
Jnk (c-jun kinases) phosphorylation and activation mediated by activated human tak1
(R-RNO-450321)
Map kinase activation
(R-RNO-450294)
Mapk targets/ nuclear events mediated by map kinases
(R-RNO-450282)
Myd88 cascade initiated on plasma membrane
(R-RNO-975871)
Myd88 dependent cascade initiated on endosome
(R-RNO-975155)
Myd88-independent tlr4 cascade
(R-RNO-166166)
Myd88:mal(tirap) cascade initiated on plasma membrane
(R-RNO-166058)
Oxidative stress induced senescence
(R-RNO-2559580)
Signaling by interleukins
(R-RNO-449147)
Toll-like receptor cascades
(R-RNO-168898)
Toll like receptor 2 (tlr2) cascade
(R-RNO-181438)
Toll like receptor 3 (tlr3) cascade
(R-RNO-168164)
Toll like receptor 4 (tlr4) cascade
(R-RNO-166016)
Toll like receptor 5 (tlr5) cascade
(R-RNO-168176)
Toll like receptor 7/8 (tlr7/8) cascade
(R-RNO-168181)
Toll like receptor 9 (tlr9) cascade
(R-RNO-168138)
Toll like receptor 10 (tlr10) cascade
(R-RNO-168142)
Toll like receptor tlr1:tlr2 cascade
(R-RNO-168179)
Toll like receptor tlr6:tlr2 cascade
(R-RNO-168188)
Traf6 mediated induction of nfkb and map kinases upon tlr7/8 or 9 activation
(R-RNO-975138)
Trif(ticam1)-mediated tlr4 signaling
(R-RNO-937061)
Atp binding
(GO:0005524)
Cellular hyperosmotic response
(GO:0071474)
Cytoplasm
(GO:0005737)
Glutamatergic synapse
(GO:0098978)
Jnk cascade
(GO:0007254)
Jun kinase activity
(GO:0004705)
Locomotor rhythm
(GO:0045475)
Mitochondrion
(GO:0005739)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neurotransmitter receptor transport to postsynaptic membrane
(GO:0098969)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Perikaryon
(GO:0043204)
Phosphorylation
(GO:0016310)
Plasma membrane
(GO:0005886)
Postsynaptic density
(GO:0014069)
Postsynaptic golgi apparatus
(GO:0150051)
Protein binding
(GO:0005515)
Protein serine kinase activity
(GO:0106310)
Regulation of circadian rhythm
(GO:0042752)
Response to light stimulus
(GO:0009416)
Rhythmic process
(GO:0048511)
Vesicle-mediated transport in synapse
(GO:0099003)

Other Information

Proteins

Mitogen-activated protein kinase 10
A6K5V7_RAT

Genular Protein ID: 1335632147

Symbol: MK10_RAT

Name: Mitogen-activated protein kinase 10

UniProtKB Accession Codes:

P49187 B0VXR6 D3ZQ33

Database IDs:

Citations:

PubMed ID: 8177321

Title: The stress-activated protein kinase subfamily of c-Jun kinases.

PubMed ID: 8177321

DOI: 10.1038/369156a0

PubMed ID: 21076496

Title: Regulation of stress-associated scaffold proteins JIP1 and JIP3 on the c-Jun NH2-terminal kinase in ischemia-reperfusion.

PubMed ID: 21076496

DOI: 10.1139/y10-088

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

PubMed ID: 11090355

Title: Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3.

PubMed ID: 11090355

DOI: 10.1126/science.290.5496.1574

PubMed ID: 12424734

Title: JNK3 contributes to c-jun induction and apoptosis in 4-hydroxynonenal-treated sympathetic neurons.

PubMed ID: 12424734

DOI: 10.1002/jnr.10437

PubMed ID: 15944381

Title: Physiological regulation of the beta-amyloid precursor protein signaling domain by c-Jun N-terminal kinase JNK3 during neuronal differentiation.

PubMed ID: 15944381

DOI: 10.1523/jneurosci.4883-04.2005

PubMed ID: 18408005

Title: The beta-arrestin-2 scaffold protein promotes c-Jun N-terminal kinase-3 activation by binding to its nonconserved N terminus.

PubMed ID: 18408005

DOI: 10.1074/jbc.m710006200

Sequence Information:

Length: 464
Mass: 52532
Checksum: 1B08210326F4EEDD
Sequence:

MSLHFLYYCS EPTLDVKIAF CQGFDKHVDV SSVVKHYNMS KSKVDNQFYS VEVGDSTFTV 
LKRYQNLKPI GSGAQGIVCA AYDAVLDRNV AIKKLSRPFQ NQTHAKRAYR ELVLMKCVNH 
KNIISLLNVF TPQKTLEEFQ DVYLVMELMD ANLCQVIQME LDHERMSYLL YQMLCGIKHL 
HSAGIIHRDL KPSNIVVKSD CTLKILDFGL ARTAGTSFMM TPYVVTRYYR APEVILGMGY 
KENVDIWSVG CIMGEMVRHK ILFPGRDYID QWNKVIEQLG TPCPEFMKKL QPTVRNYVEN 
RPKYAGLTFP KLFPDSLFPA DSEHNKLKAS QARDLLSKML VIDPAKRISV DDALQHPYIN 
VWYDPAEVEA PPPQIYDKQL DEREHTIEEW KELIYKEVMN SEEKTKNGVV KGQPSPSGAA 
VNSSESLPPS SSVNDISSMS TDQTLASDTD SSLEASAGPL GCCR

Genular Protein ID: 3481257741

Symbol: A6K5V7_RAT

Name: N/A

UniProtKB Accession Codes:

A6K5V7

Database IDs:

Citations:

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

Length: 464
Mass: 52504
Checksum: 3E61407FCF31A342
Sequence:

MSLHFLYYCS EPTLDVKIAF CQGFDKHVDV SSVAKHYNMS KSKVDNQFYS VEVGDSTFTV 
LKRYQNLKPI GSGAQGIVCA AYDAVLDRNV AIKKLSRPFQ NQTHAKRAYR ELVLMKCVNH 
KNIISLLNVF TPQKTLEEFQ DVYLVMELMD ANLCQVIQME LDHERMSYLL YQMLCGIKHL 
HSAGIIHRDL KPSNIVVKSD CTLKILDFGL ARTAGTSFMM TPYVVTRYYR APEVILGMGY 
KENVDIWSVG CIMGEMVRHK ILFPGRDYID QWNKVIEQLG TPCPEFMKKL QPTVRNYVEN 
RPKYAGLTFP KLFPDSLFPA DSEHNKLKAS QARDLLSKML VIDPAKRISV DDALQHPYIN 
VWYDPAEVEA PPPQIYDKQL DEREHTIEEW KELIYKEVMN SEEKTKNGVV KGQPSPSGAA 
VNSSESLPPS SSVNDISSMS TDQTLASDTD SSLEASAGPL GCCR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mapk10

Associated with

Other Information

The stress-activated protein kinase subfamily of c-Jun kinases. PubMed ID: 8177321

Regulation of stress-associated scaffold proteins JIP1 and JIP3 on the c-Jun NH2-terminal kinase in ischemia-reperfusion. PubMed ID: 21076496

Genome sequence of the Brown Norway rat yields insights into mammalian evolution. PubMed ID: 15057822

Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. PubMed ID: 11090355

JNK3 contributes to c-jun induction and apoptosis in 4-hydroxynonenal-treated sympathetic neurons. PubMed ID: 12424734

Physiological regulation of the beta-amyloid precursor protein signaling domain by c-Jun N-terminal kinase JNK3 during neuronal differentiation. PubMed ID: 15944381

The beta-arrestin-2 scaffold protein promotes c-Jun N-terminal kinase-3 activation by binding to its nonconserved N terminus. PubMed ID: 18408005

Gene and alternative splicing annotation with AIR. PubMed ID: 15632090