Smo | ENSRNOG00000008332 | NCBI 25273

Details for: Smo

Gene ID: 25273

Symbol: Smo

Ensembl ID: ENSRNOG00000008332

Description: smoothened, frizzled class receptor

Associated with

Anterior/posterior pattern specification
(GO:0009952)
Apoptotic process
(GO:0006915)
Astrocyte activation
(GO:0048143)
Atrial septum morphogenesis
(GO:0060413)
Axon extension involved in axon guidance
(GO:0048846)
Camp-dependent protein kinase inhibitor activity
(GO:0004862)
Cell development
(GO:0048468)
Cell fate specification
(GO:0001708)
Cell population proliferation
(GO:0008283)
Cellular response to cholesterol
(GO:0071397)
Central nervous system development
(GO:0007417)
Central nervous system neuron differentiation
(GO:0021953)
Cerebellar cortex morphogenesis
(GO:0021696)
Cerebral cortex development
(GO:0021987)
Commissural neuron axon guidance
(GO:0071679)
Contact inhibition
(GO:0060242)
Dentate gyrus development
(GO:0021542)
Determination of left/right asymmetry in lateral mesoderm
(GO:0003140)
Determination of left/right symmetry
(GO:0007368)
Developmental growth
(GO:0048589)
Digestive tract development
(GO:0048565)
Dopaminergic neuron differentiation
(GO:0071542)
Dorsal/ventral neural tube patterning
(GO:0021904)
Dorsal/ventral pattern formation
(GO:0009953)
Embryonic organ development
(GO:0048568)
Epithelial-mesenchymal cell signaling
(GO:0060684)
Epithelial cell differentiation
(GO:0030855)
Epithelial cell proliferation
(GO:0050673)
Facial nerve development
(GO:0021561)
Forebrain morphogenesis
(GO:0048853)
Gene expression
(GO:0010467)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Hair follicle development
(GO:0001942)
Hair follicle morphogenesis
(GO:0031069)
Heart looping
(GO:0001947)
Heart morphogenesis
(GO:0003007)
Homeostasis of number of cells within a tissue
(GO:0048873)
In utero embryonic development
(GO:0001701)
Left/right axis specification
(GO:0070986)
Mammary gland epithelial cell differentiation
(GO:0060644)
Mesenchymal to epithelial transition
(GO:0060231)
Mesenchymal to epithelial transition involved in metanephric renal vesicle formation
(GO:0072285)
Midgut development
(GO:0007494)
Multicellular organism growth
(GO:0035264)
Myoblast migration
(GO:0051451)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of epithelial cell differentiation
(GO:0030857)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of hair follicle development
(GO:0051799)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of protein phosphorylation
(GO:0001933)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neural crest cell migration
(GO:0001755)
Neuroblast proliferation
(GO:0007405)
Neuron projection regeneration
(GO:0031102)
Odontogenesis of dentin-containing tooth
(GO:0042475)
Ossification
(GO:0001503)
Osteoblast differentiation
(GO:0001649)
Oxysterol binding
(GO:0008142)
Pancreas morphogenesis
(GO:0061113)
Patched binding
(GO:0005113)
Pattern specification process
(GO:0007389)
Positive regulation of autophagy
(GO:0010508)
Positive regulation of branching involved in ureteric bud morphogenesis
(GO:0090190)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of mesenchymal cell proliferation
(GO:0002053)
Positive regulation of multicellular organism growth
(GO:0040018)
Positive regulation of neuroblast proliferation
(GO:0002052)
Positive regulation of organ growth
(GO:0046622)
Positive regulation of protein import into nucleus
(GO:0042307)
Positive regulation of smoothened signaling pathway
(GO:0045880)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein import into nucleus
(GO:0006606)
Protein kinase a catalytic subunit binding
(GO:0034236)
Protein localization to nucleus
(GO:0034504)
Protein sequestering activity
(GO:0140311)
Protein stabilization
(GO:0050821)
Regulation of gene expression
(GO:0010468)
Regulation of localization
(GO:0032879)
Regulation of somatic stem cell population maintenance
(GO:1904672)
Response to organic substance
(GO:0010033)
Skeletal muscle fiber development
(GO:0048741)
Smoothened signaling pathway
(GO:0007224)
Smooth muscle tissue development
(GO:0048745)
Somite development
(GO:0061053)
Spermatogenesis
(GO:0007283)
Spinal cord dorsal/ventral patterning
(GO:0021513)
Thalamus development
(GO:0021794)
Type b pancreatic cell development
(GO:0003323)
Vasculogenesis
(GO:0001570)
Ventral midline determination
(GO:0007371)

Other Information

Proteins

Protein smoothened

Genular Protein ID: 3045234713

Symbol: SMO_RAT

Name: Protein smoothened

UniProtKB Accession Codes:

P97698

Database IDs:

Citations:

PubMed ID: 8906787

Title: The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog.

PubMed ID: 8906787

DOI: 10.1038/384129a0

Sequence Information:

Length: 793
Mass: 87376
Checksum: 27B88178B2565FB9
Sequence:

MAAGRPVRGP ELAPRRLLQL LLLVLLGGRG RGAALSGNVT GPGPRSAGGS ARRNAPVTSP 
PPPLLSHCGR AAHCEPLRYN VCLGSALPYG ATTTLLAGDS DSQEEAHSKL VLWSGLRNAP 
RCWAVIQPLL CAVYMPKCEN DRVELPSRTL CQATRGPCAI VERERGWPDF LRCTPDHFPE 
GCPNEVQNIK FNSSGQCEAP LVRTDNPKSW YEDVEGCGIQ CQNPLFTEAE HQDMHSYIAA 
FGAVTGLCTL FTLATFVADW RNSNRYPAVI LFYVNACFFV GSIGWLAQFM DGARREIVCR 
ADGTMRFGEP TSSETLSCVI IFVIVYYALM AGVVWFVVLT YAWHTSFKAL GTTYQPLSGK 
TSYFHLLTWS LPFVLTVAIL AVAQVDGDSV SGICFVGYKN YRYRAGFVLA PIGLVLIVGG 
YFLIRGVMTL FSIKSNHPGL LSEKAASKIN ETMLRLGIFG FLAFGFVLIT FSCHFYDFFN 
QAEWERSFRD YVLCQANVTI GLPTKKPIPD CEIKNRPSLL VEKINLFAMF GTGIAMSTWV 
WTKATLLIWR RTWCRLTGHS DDEPKRIKKS KMIAKAFSKR RELLQNPGQE LSFSMHTVSH 
DGPVAGLAFE LNEPSADVSS AWAQHVTKMV ARRGAILPQD VSVTPVATPV PPEEQANLWL 
VEAEISPELE KRLGRKKKRR KRKKEVCPLG PAPELHHSAP VPATSAVPRL PQLPRQKCLV 
AANAWGTGEP CRQGAWTVVS NPFCPEPSPH QDPFLPGASA PRVWAQGRLQ GLGSIHSRTN 
LMEAELLDAD SDF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Smo

Associated with

Other Information

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. PubMed ID: 8906787

Database document:

PubMed ID: 8906787