Details for: Igfbp5

Gene ID: 25285

Symbol: Igfbp5

Ensembl ID: ENSRNOG00000017206

Description: insulin-like growth factor binding protein 5

Associated with

  • Metabolism of proteins
    (R-RNO-392499)
  • Post-translational protein modification
    (R-RNO-597592)
  • Post-translational protein phosphorylation
    (R-RNO-8957275)
  • Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
    (R-RNO-381426)
  • Cellular response to camp
    (GO:0071320)
  • Cellular response to organic cyclic compound
    (GO:0071407)
  • Extracellular space
    (GO:0005615)
  • Female pregnancy
    (GO:0007565)
  • Fibronectin binding
    (GO:0001968)
  • Glucose homeostasis
    (GO:0042593)
  • Hair follicle morphogenesis
    (GO:0031069)
  • Insulin-like growth factor binding
    (GO:0005520)
  • Insulin-like growth factor i binding
    (GO:0031994)
  • Insulin-like growth factor ii binding
    (GO:0031995)
  • Insulin-like growth factor receptor signaling pathway
    (GO:0048009)
  • Insulin-like growth factor ternary complex
    (GO:0042567)
  • Intracellular signal transduction
    (GO:0035556)
  • Lung alveolus development
    (GO:0048286)
  • Mammary gland involution
    (GO:0060056)
  • Negative regulation of cell migration
    (GO:0030336)
  • Negative regulation of growth
    (GO:0045926)
  • Negative regulation of insulin-like growth factor receptor signaling pathway
    (GO:0043569)
  • Negative regulation of muscle tissue development
    (GO:1901862)
  • Negative regulation of osteoblast differentiation
    (GO:0045668)
  • Negative regulation of skeletal muscle hypertrophy
    (GO:1904205)
  • Negative regulation of smooth muscle cell migration
    (GO:0014912)
  • Negative regulation of smooth muscle cell proliferation
    (GO:0048662)
  • Negative regulation of translation
    (GO:0017148)
  • Osteoblast differentiation
    (GO:0001649)
  • Positive regulation of insulin-like growth factor receptor signaling pathway
    (GO:0043568)
  • Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051897)
  • Positive regulation of vascular associated smooth muscle cell migration
    (GO:1904754)
  • Positive regulation of vascular associated smooth muscle cell proliferation
    (GO:1904707)
  • Regulation of cell growth
    (GO:0001558)
  • Regulation of growth
    (GO:0040008)
  • Regulation of insulin-like growth factor receptor signaling pathway
    (GO:0043567)
  • Response to growth hormone
    (GO:0060416)
  • Response to organic cyclic compound
    (GO:0014070)
  • Striated muscle cell differentiation
    (GO:0051146)
  • Type b pancreatic cell proliferation
    (GO:0044342)

Other Information

Genular Protein ID: 4116268327

Symbol: IBP5_RAT

Name: Insulin-like growth factor-binding protein 5

UniProtKB Accession Codes:

P24594

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 CDD 1 CTD 1 EMBL 2 Ensembl 4 ExpressionAtlas 1 GO 36 Gene3D 2 GeneTree 1 Genevisible 1 InParanoid 1 InterPro 7 KEGG 1 MEROPS 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 4 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 2 RefSeq 1 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 UniProtKB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 1709938

Title: Identification of five different insulin-like growth factor binding proteins (IGFBPs) from adult rat serum and molecular cloning of a novel IGFBP-5 in rat and human.

PubMed ID: 1709938

DOI: 10.1016/s0021-9258(18)99272-0

PubMed ID: 7679898

Title: Cloning of the rat insulin-like growth factor binding protein-5 gene and DNA sequence analysis of its promoter region.

PubMed ID: 7679898

DOI: 10.1006/bbrc.1993.1154

Sequence Information:

  • Length: 271
  • Mass: 30298
  • Checksum: 545B4C48F9BB5493
  • Sequence:
    • MVISVVLLLL AACAVPAQGL GSFVHCEPCD EKALSMCPPS PLGCELVKEP GCGCCMTCAL 
AEGQSCGVYT ERCAQGLRCL PRQDEEKPLH ALLHGRGVCL NEKSYGEQTK IERDSREHEE 
PTTSEMAEET YSPKVFRPKH TRISELKAEA VKKDRRKKLT QSKFVGGAEN TAHPRVIPAP 
EMRQESDQGP CRRHMEASLQ EFKASPRMVP RAVYLPNCDR KGFYKRKQCK PSRGRKRGIC 
WCVDKYGMKL PGMEYVDGDF QCHAFDSSNV E

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.