Acadl | ENSRNOG00000012966 | NCBI 25287

Details for: Acadl

Gene ID: 25287

Symbol: Acadl

Ensembl ID: ENSRNOG00000012966

Description: acyl-CoA dehydrogenase, long chain

Associated with

Beta oxidation of lauroyl-coa to decanoyl-coa-coa
(R-RNO-77310)
Beta oxidation of myristoyl-coa to lauroyl-coa
(R-RNO-77285)
Fatty acid metabolism
(R-RNO-8978868)
Metabolism
(R-RNO-1430728)
Metabolism of lipids
(R-RNO-556833)
Mitochondrial fatty acid beta-oxidation
(R-RNO-77289)
Mitochondrial fatty acid beta-oxidation of saturated fatty acids
(R-RNO-77286)
Carnitine catabolic process
(GO:0042413)
Carnitine metabolic process, coa-linked
(GO:0019254)
Cellular lipid catabolic process
(GO:0044242)
Cytoplasm
(GO:0005737)
Fatty-acyl-coa binding
(GO:0000062)
Fatty acid beta-oxidation using acyl-coa dehydrogenase
(GO:0033539)
Fatty acid catabolic process
(GO:0009062)
Flavin adenine dinucleotide binding
(GO:0050660)
Identical protein binding
(GO:0042802)
Long-chain fatty acid catabolic process
(GO:0042758)
Long-chain fatty acyl-coa dehydrogenase activity
(GO:0004466)
Mitochondrial matrix
(GO:0005759)
Mitochondrial membrane
(GO:0031966)
Mitochondrion
(GO:0005739)
Negative regulation of fatty acid biosynthetic process
(GO:0045717)
Negative regulation of fatty acid oxidation
(GO:0046322)
Palmitoyl-coa oxidase activity
(GO:0016401)
Positive regulation of cold-induced thermogenesis
(GO:0120162)
Regulation of cholesterol metabolic process
(GO:0090181)
Response to cold
(GO:0009409)
Temperature homeostasis
(GO:0001659)

Other Information

Proteins

Long-chain specific acyl-CoA dehydrogenase, mitochondrial

Genular Protein ID: 2714526564

Symbol: ACADL_RAT

Name: Long-chain specific acyl-CoA dehydrogenase, mitochondrial

UniProtKB Accession Codes:

P15650

Database IDs:

Citations:

PubMed ID: 2777793

Title: Molecular cloning and nucleotide sequence of cDNAs encoding the precursors of rat long chain acyl-coenzyme A, short chain acyl-coenzyme A, and isovaleryl-coenzyme A dehydrogenases. Sequence homology of four enzymes of the acyl-CoA dehydrogenase family.

PubMed ID: 2777793

DOI: 10.1016/s0021-9258(18)71624-4

PubMed ID: 8268228

Title: Tissue specific and developmental expression of rat long- and medium-chain acyl-CoA dehydrogenases.

PubMed ID: 8268228

DOI: 10.1016/0167-4781(93)90015-6

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3968063

Title: Purification and characterization of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. Isolation of the holo- and apoenzymes and conversion of the apoenzyme to the holoenzyme.

PubMed ID: 3968063

DOI: 10.1016/s0021-9258(20)71245-7

PubMed ID: 3813556

Title: Biosynthesis of four rat liver mitochondrial acyl-CoA dehydrogenases: in vitro synthesis, import into mitochondria, and processing of their precursors in a cell-free system and in cultured cells.

PubMed ID: 3813556

DOI: 10.1016/0003-9861(87)90072-5

PubMed ID: 15466478

Title: Leaky beta-oxidation of a trans-fatty acid: incomplete beta-oxidation of elaidic acid is due to the accumulation of 5-trans-tetradecenoyl-CoA and its hydrolysis and conversion to 5-trans-tetradecenoylcarnitine in the matrix of rat mitochondria.

PubMed ID: 15466478

DOI: 10.1074/jbc.m409640200

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 430
Mass: 47873
Checksum: BEE1C7E0FDD84D2E
Sequence:

MAARLLLRSL RVLSARSATL PPPSARCSHS GAEARLETPS AKKLTDIGIR RIFSSEHDIF 
RESVRKFFQE EVIPYHEEWE KAGEVSRELW EKAGKQGLLG INIAEKHGGI GGDLLSTAVT 
WEEQAYSNCT GPGFSLHSDI VMPYIANYGT KEQIEQFIPQ MTAGKCIGAI AMTEPGAGSD 
LQGVRTNAKR SGSDWILNGS KVFITNGWLS DLVIVVAVTN REARSPAHGI SLFLVENGMK 
GFIKGKKLHK MGMKAQDTAE LFFEDVRLPA SALLGEENKG FYYLMQELPQ ERLLIADLAI 
SACEFMFEET RNYVRQRKAF GKTVAHIQTV QHKLAELKTN ICVTRAFVDS CLQLHETKRL 
DSASASMAKY WASELQNTVA YQCVQLHGGW GYMWEYPIAK AYVDARVQPI YGGTNEIMKE 
LIARQIVSDS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Acadl

Associated with

Other Information

Molecular cloning and nucleotide sequence of cDNAs encoding the precursors of rat long chain acyl-coenzyme A, short chain acyl-coenzyme A, and isovaleryl-coenzyme A dehydrogenases. Sequence homology of four enzymes of the acyl-CoA dehydrogenase family. PubMed ID: 2777793

Tissue specific and developmental expression of rat long- and medium-chain acyl-CoA dehydrogenases. PubMed ID: 8268228

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Purification and characterization of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. Isolation of the holo- and apoenzymes and conversion of the apoenzyme to the holoenzyme. PubMed ID: 3968063

Biosynthesis of four rat liver mitochondrial acyl-CoA dehydrogenases: in vitro synthesis, import into mitochondria, and processing of their precursors in a cell-free system and in cultured cells. PubMed ID: 3813556

Leaky beta-oxidation of a trans-fatty acid: incomplete beta-oxidation of elaidic acid is due to the accumulation of 5-trans-tetradecenoyl-CoA and its hydrolysis and conversion to 5-trans-tetradecenoylcarnitine in the matrix of rat mitochondria. PubMed ID: 15466478

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903