Bglap | ENSRNOG00000019607 | NCBI 25295

Details for: Bglap

Gene ID: 25295

Symbol: Bglap

Ensembl ID: ENSRNOG00000019607

Description: bone gamma-carboxyglutamate protein

Associated with

Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
(R-RNO-159854)
Gamma-carboxylation of protein precursors
(R-RNO-159740)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
(R-RNO-163841)
Metabolism of proteins
(R-RNO-392499)
Post-translational protein modification
(R-RNO-597592)
Removal of aminoterminal propeptides from gamma-carboxylated proteins
(R-RNO-159782)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the golgi apparatus
(R-RNO-159763)
Biomineral tissue development
(GO:0031214)
Bone development
(GO:0060348)
Brain development
(GO:0007420)
Calcium-dependent protein binding
(GO:0048306)
Calcium ion binding
(GO:0005509)
Cell projection
(GO:0042995)
Cellular response to bmp stimulus
(GO:0071773)
Cellular response to growth factor stimulus
(GO:0071363)
Cellular response to insulin stimulus
(GO:0032869)
Cellular response to vitamin d
(GO:0071305)
Cellular response to zinc ion starvation
(GO:0034224)
Cognition
(GO:0050890)
Collagen-containing extracellular matrix
(GO:0062023)
Cytoplasm
(GO:0005737)
Dendrite
(GO:0030425)
Dephosphorylation
(GO:0016311)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Glucose homeostasis
(GO:0042593)
Hormone activity
(GO:0005179)
Hydroxyapatite binding
(GO:0046848)
Ion binding
(GO:0043167)
Learning or memory
(GO:0007611)
Negative regulation of bone development
(GO:1903011)
Ossification
(GO:0001503)
Osteoblast development
(GO:0002076)
Osteoblast differentiation
(GO:0001649)
Perikaryon
(GO:0043204)
Positive regulation of neurotransmitter secretion
(GO:0001956)
Regulation of bone mineralization
(GO:0030500)
Regulation of cellular response to insulin stimulus
(GO:1900076)
Regulation of testosterone biosynthetic process
(GO:2000224)
Response to activity
(GO:0014823)
Response to estrogen
(GO:0043627)
Response to ethanol
(GO:0045471)
Response to glucocorticoid
(GO:0051384)
Response to gravity
(GO:0009629)
Response to hydroxyisoflavone
(GO:0033594)
Response to inorganic substance
(GO:0010035)
Response to insulin
(GO:0032868)
Response to macrophage colony-stimulating factor
(GO:0036005)
Response to mechanical stimulus
(GO:0009612)
Response to nutrient levels
(GO:0031667)
Response to organic cyclic compound
(GO:0014070)
Response to testosterone
(GO:0033574)
Response to vitamin d
(GO:0033280)
Response to vitamin k
(GO:0032571)
Response to xenobiotic stimulus
(GO:0009410)
Response to zinc ion
(GO:0010043)
Signal transduction
(GO:0007165)
Stem cell differentiation
(GO:0048863)
Structural constituent of bone
(GO:0008147)
Transition metal ion binding
(GO:0046914)
Type b pancreatic cell proliferation
(GO:0044342)
Vesicle
(GO:0031982)

Other Information

Proteins

Osteocalcin

Genular Protein ID: 2280319556

Symbol: OSTCN_RAT

Name: Osteocalcin

UniProtKB Accession Codes:

P04640

Database IDs:

Citations:

PubMed ID: 3019668

Title: Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones.

PubMed ID: 3019668

DOI: 10.1002/j.1460-2075.1986.tb04440.x

PubMed ID: 3875856

Title: The propeptide of rat bone gamma-carboxyglutamic acid protein shares homology with other vitamin K-dependent protein precursors.

PubMed ID: 3875856

DOI: 10.1073/pnas.82.18.6109

PubMed ID: 3265336

Title: Characterization of the rat osteocalcin gene: stimulation of promoter activity by 1,25-dihydroxyvitamin D3.

PubMed ID: 3265336

DOI: 10.1021/bi00423a003

PubMed ID: 2785907

Title: Molecular structure of the rat bone Gla protein gene and identification of putative regulatory elements.

PubMed ID: 2785907

DOI: 10.1089/dna.1.1989.8.213

PubMed ID: 2784002

Title: Structure of the rat osteocalcin gene and regulation of vitamin D-dependent expression.

PubMed ID: 2784002

DOI: 10.1073/pnas.86.4.1143

Sequence Information:

Length: 99
Mass: 10927
Checksum: 7F18F1866D4E4388
Sequence:

MRTLSLLTLL ALTAFCLSDL AGAKPSDSES DKAFMSKQEG SKVVNRLRRY LNNGLGAPAP 
YPDPLEPHRE VCELNPNCDE LADHIGFQDA YKRIYGTTV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Bglap

Associated with

Other Information

Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones. PubMed ID: 3019668

The propeptide of rat bone gamma-carboxyglutamic acid protein shares homology with other vitamin K-dependent protein precursors. PubMed ID: 3875856

Characterization of the rat osteocalcin gene: stimulation of promoter activity by 1,25-dihydroxyvitamin D3. PubMed ID: 3265336