Comp | ENSRNOG00000048472 | NCBI 25304

Details for: Comp

Gene ID: 25304

Symbol: Comp

Ensembl ID: ENSRNOG00000048472

Description: cartilage oligomeric matrix protein

Associated with

Ecm proteoglycans
(R-RNO-3000178)
Extracellular matrix organization
(R-RNO-1474244)
Integrin cell surface interactions
(R-RNO-216083)
Apoptotic process
(GO:0006915)
Artery morphogenesis
(GO:0048844)
Blood coagulation
(GO:0007596)
Bmp binding
(GO:0036122)
Bmp signaling pathway
(GO:0030509)
Bone growth
(GO:0098868)
Bone mineralization
(GO:0030282)
Bone morphogenesis
(GO:0060349)
Calcium ion binding
(GO:0005509)
Cartilage development
(GO:0051216)
Cartilage homeostasis
(GO:1990079)
Cell adhesion
(GO:0007155)
Cellular senescence
(GO:0090398)
Chondrocyte development
(GO:0002063)
Chondrocyte proliferation
(GO:0035988)
Collagen-containing extracellular matrix
(GO:0062023)
Collagen binding
(GO:0005518)
Collagen fibril organization
(GO:0030199)
Endochondral bone growth
(GO:0003416)
Extracellular matrix structural constituent
(GO:0005201)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Fibronectin binding
(GO:0001968)
Growth plate cartilage development
(GO:0003417)
Heparan sulfate proteoglycan binding
(GO:0043395)
Heparin binding
(GO:0008201)
Integrin binding
(GO:0005178)
Limb development
(GO:0060173)
Multicellular organism growth
(GO:0035264)
Muscle cell development
(GO:0055001)
Musculoskeletal movement
(GO:0050881)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of hemostasis
(GO:1900047)
Neuromuscular process
(GO:0050905)
Ossification
(GO:0001503)
Platelet aggregation
(GO:0070527)
Positive regulation of chondrocyte proliferation
(GO:1902732)
Protease binding
(GO:0002020)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Protein homooligomerization
(GO:0051260)
Protein processing
(GO:0016485)
Protein secretion
(GO:0009306)
Proteoglycan binding
(GO:0043394)
Regulation of bone mineralization
(GO:0030500)
Regulation of gene expression
(GO:0010468)
Response to unfolded protein
(GO:0006986)
Skeletal system development
(GO:0001501)
Skin development
(GO:0043588)
Tendon development
(GO:0035989)
Vascular associated smooth muscle cell development
(GO:0097084)
Vascular associated smooth muscle contraction
(GO:0014829)
Vitamin d binding
(GO:0005499)

Other Information

Proteins

COMP_RAT

Genular Protein ID: 401853325

Symbol: COMP_RAT

Name: N/A

UniProtKB Accession Codes:

P35444

Database IDs:

Citations:

PubMed ID: 1429587

Title: COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins.

PubMed ID: 1429587

DOI: 10.1016/s0021-9258(18)41677-8

PubMed ID: 20019333

Title: Cartilage oligomeric matrix protein maintains the contractile phenotype of vascular smooth muscle cells by interacting with alpha(7)beta(1) integrin.

PubMed ID: 20019333

DOI: 10.1161/circresaha.109.202762

PubMed ID: 8864111

Title: The crystal structure of a five-stranded coiled coil in COMP: a prototype ion channel?

PubMed ID: 8864111

DOI: 10.1126/science.274.5288.761

Sequence Information:

Length: 755
Mass: 82664
Checksum: AB48888FE093C598
Sequence:

MSPTACVLVL ALAALRATGQ GQIPLGGDLA PQMLRELQET NAALQDVREL LRHRVKEITF 
LKNTVMECDA CGMQPARTPG LSVRPVALCA PGSCFPGVVC TETATGARCG PCPPGYTGNG 
SHCTDVNECN AHPCFPRVRC INTSPGFHCE ACPPGFSGPT HEGVGLTFAK TNKQVCTDIN 
ECETGQHNCV PNSVCVNTRG SFQCGPCQPG FVGDQRSGCQ RRGQHFCPDG SPSPCHEKAD 
CILERDGSRS CVCAVGWAGN GLLCGRDTDL DGFPDEKLRC SERQCRKDNC VTVPNSGQED 
VDRDRIGDAC DPDADGDGVP NEQDNCPLVR NPDQRNSDKD KWGDACDNCR SQKNDDQKDT 
DRDGQGDACD DDIDGDRIRN VADNCPRVPN FDQSDSDGDG VGDACDNCPQ KDNPDQRDVD 
HDFVGDACDS DQDQDGDGHQ DSRDNCPTVP NSAQQDSDHD GKGDACDDDD DNDGVPDSRD 
NCRLVPNPGQ EDNDRDGVGD ACQGDFDADK VIDKIDVCPE NAEVTLTDFR AFQTVVLDPE 
GDAQIDPNWV VLNQGMEIVQ TMNSDPGLAV GYTAFNGVDF EGTFHVNTAT DDDYAGFIFG 
YQDSSSFYVV MWKQMEQTYW QANPFRAVAE PGIQLKAVKS STGPGEQLRN ALWHTGDTAS 
QVRLLWKDPR NVGWKDKTSY RWFLQHRPQV GYIRVRFYEG PELVADSNVV LDTAMRGGRL 
GVFCFSQENI IWANLRYRCN DTIPEDYERH RLRRA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.