Ephx1 | ENSRNOG00000003515 | NCBI 25315

Details for: Ephx1

Gene ID: 25315

Symbol: Ephx1

Ensembl ID: ENSRNOG00000003515

Description: epoxide hydrolase 1

Associated with

Biological oxidations
(R-RNO-211859)
Metabolism
(R-RNO-1430728)
Phase i - functionalization of compounds
(R-RNO-211945)
Arachidonic acid metabolic process
(GO:0019369)
Aromatic compound catabolic process
(GO:0019439)
Cellular aromatic compound metabolic process
(GO:0006725)
Cellular response to glucocorticoid stimulus
(GO:0071385)
Cellular response to organic substance
(GO:0071310)
Cis-stilbene-oxide hydrolase activity
(GO:0033961)
Diol biosynthetic process
(GO:0034312)
Endoplasmic reticulum membrane
(GO:0005789)
Enzyme binding
(GO:0019899)
Epoxide hydrolase activity
(GO:0004301)
Epoxide metabolic process
(GO:0097176)
Intracellular membrane-bounded organelle
(GO:0043231)
Lipid metabolic process
(GO:0006629)
Liver development
(GO:0001889)
Membrane
(GO:0016020)
Oxysterol binding
(GO:0008142)
Response to organic cyclic compound
(GO:0014070)
Response to toxic substance
(GO:0009636)

Other Information

Proteins

Epoxide hydratase

Genular Protein ID: 3492926542

Symbol: HYEP_RAT

Name: Epoxide hydratase

UniProtKB Accession Codes:

P07687

Database IDs:

Citations:

PubMed ID: 3032949

Title: Structure and organization of the microsomal xenobiotic epoxide hydrolase gene.

PubMed ID: 3032949

DOI: 10.1016/s0021-9258(18)45663-3

PubMed ID: 3755318

Title: Complementary DNA and amino acid sequence of rat liver microsomal, xenobiotic epoxide hydrolase.

PubMed ID: 3755318

DOI: 10.1016/0003-9861(86)90408-x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9245728

Title: The membrane anchor of microsomal epoxide hydrolase from human, rat, and rabbit displays an unexpected membrane topology.

PubMed ID: 9245728

DOI: 10.1006/bbrc.1997.7044

PubMed ID: 9854022

Title: Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate.

PubMed ID: 9854022

DOI: 10.1042/bj3370037

PubMed ID: 15047867

Title: Organellar proteomics reveals Golgi arginine dimethylation.

PubMed ID: 15047867

DOI: 10.1091/mbc.e04-02-0101

Sequence Information:

Length: 455
Mass: 52582
Checksum: 437A15BBCD6861FA
Sequence:

MWLELVLASL LGFVIYWFVS RDKEETLPLG DGWWGPGSKP SAKEDESIRP FKVETSDEEI 
KDLHQRIDRF RASPPLEGSR FHYGFNSNYM KKVVSYWRNE FDWRKQVEIL NQYPHFKTKI 
EGLDIHFIHV KPPQLPSGRT PKPLLMVHGW PGSFYEFYKI IPLLTDPKSH GLSDEHVFEV 
ICPSIPGYGY SEASSKKGLN SVATARIFYK LMTRLGFQKF YIQGGDWGSL ICTNMAQMVP 
NHVKGLHLNM AFISRSFYTM TPLLGQRFGR FLGYTEKDIE LLYPYKEKVF YSIMRESGYL 
HIQATKPDTV GCALNDSPVG LAAYILEKFS TWTKSEYREL EDGGLERKFS LDDLLVNIMI 
YWTTGTIVSS QRYYKENLGQ GIMVHKHEGM KVFVPTGFSA FPSELLHAPE KWVKVKYPKL 
ISYSYMERGG HFAAFEEPKL LAQDIRKFVS LAELQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ephx1

Associated with

Other Information

Structure and organization of the microsomal xenobiotic epoxide hydrolase gene. PubMed ID: 3032949

Complementary DNA and amino acid sequence of rat liver microsomal, xenobiotic epoxide hydrolase. PubMed ID: 3755318

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The membrane anchor of microsomal epoxide hydrolase from human, rat, and rabbit displays an unexpected membrane topology. PubMed ID: 9245728

Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate. PubMed ID: 9854022