Details for: Mgmt

Gene ID: 25332

Symbol: Mgmt

Ensembl ID: ENSRNOG00000016038

Description: O-6-methylguanine-DNA methyltransferase

Associated with

Other Information

Genular Protein ID: 880156526

Symbol: MGMT_RAT

Name: Methylated-DNA--protein-cysteine methyltransferase

UniProtKB Accession Codes:

P24528

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 CDD 1 CTD 1 ChEBI 19 EC 3 EMBL 3 Ensembl 4 GO 21 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 RefSeq 1 Rhea 10 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UniProtKB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 2049083

Title: cDNA cloning of the rat O6-methylguanine-DNA-methyltransferase.

PubMed ID: 2049083

DOI: 10.1016/0006-291x(91)91830-6

PubMed ID: 2013136

Title: Isolation and cDNA cloning of a rat O6-alkylguanine-DNA-alkyltransferase gene, molecular analysis of expression in rat liver.

PubMed ID: 2013136

DOI: 10.1093/carcin/12.4.727

PubMed ID: 8467487

Title: Ribozyme-mediated modulation of human O6-methylguanine-DNA methyltransferase expression.

PubMed ID: 8467487

PubMed ID: 1945835

Title: Cloning and expression of cDNA for rat O6-methylguanine-DNA methyltransferase.

PubMed ID: 1945835

DOI: 10.1093/nar/19.20.5597

PubMed ID: 8202360

Title: Specificities of human, rat and E. coli O6-methylguanine-DNA methyltransferases towards the repair of O6-methyl and O6-ethylguanine in DNA.

PubMed ID: 8202360

DOI: 10.1093/nar/22.9.1613

Sequence Information:

  • Length: 209
  • Mass: 22244
  • Checksum: 61F8F51C8937D4A7
  • Sequence:
    • MAEICKMKYT VLDSPLGKIE LSGCERGLHG IRFLSGKTPN TDPTEAPACP EVLGGPEGVP 
EPLVQCTAWL EAYFHEPAAT EGLPLPALHH PVFQQDSFTR QVLWKLLKVV KFGEMVSYQQ 
LAALAGNPKA ARAVGGAMRS NPVPILIPCH RVIRSDGAIG NYSGGGQTVK EWLLAHEGIP 
TGQPASKGLG LIGSWLKPSF ESSSPKPSG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.