Details for: Scn2b

Gene ID: 25349

Symbol: Scn2b

Ensembl ID: ENSRNOG00000063505

Description: sodium voltage-gated channel beta subunit 2

Associated with

  • Cardiac conduction
    (GO:0061337)
  • Cardiac muscle cell action potential involved in contraction
    (GO:0086002)
  • Cardiac muscle contraction
    (GO:0060048)
  • Gene expression
    (GO:0010467)
  • Membrane depolarization during cardiac muscle cell action potential
    (GO:0086012)
  • Membrane repolarization during ventricular cardiac muscle cell action potential
    (GO:0098915)
  • Nervous system development
    (GO:0007399)
  • Plasma membrane
    (GO:0005886)
  • Protein binding
    (GO:0005515)
  • Regulation of atrial cardiac muscle cell membrane depolarization
    (GO:0060371)
  • Regulation of heart rate by cardiac conduction
    (GO:0086091)
  • Regulation of sodium ion transmembrane transporter activity
    (GO:2000649)
  • Response to heat
    (GO:0009408)
  • Response to pyrethroid
    (GO:0046684)
  • Sodium channel regulator activity
    (GO:0017080)
  • Sodium ion transmembrane transport
    (GO:0035725)
  • Sodium ion transport
    (GO:0006814)
  • T-tubule
    (GO:0030315)
  • Voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
    (GO:1902282)
  • Voltage-gated sodium channel activity
    (GO:0005248)
  • Voltage-gated sodium channel activity involved in cardiac muscle cell action potential
    (GO:0086006)
  • Voltage-gated sodium channel complex
    (GO:0001518)

Other Information

Genular Protein ID: 829399668

Symbol: SCN2B_RAT

Name: Sodium channel subunit beta-2

UniProtKB Accession Codes:

P54900

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 CTD 1 DNASU 1 EMBL 1 Ensembl 5 GO 19 Gene3D 1 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8521473

Title: Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif.

PubMed ID: 8521473

DOI: 10.1016/0092-8674(95)90121-3

PubMed ID: 9861042

Title: Interaction of voltage-gated sodium channels with the extracellular matrix molecules tenascin-C and tenascin-R.

PubMed ID: 9861042

DOI: 10.1073/pnas.95.26.15753

PubMed ID: 15178439

Title: Role of auxiliary beta1-, beta2-, and beta3-subunits and their interaction with Na(v)1.8 voltage-gated sodium channel.

PubMed ID: 15178439

DOI: 10.1016/j.bbrc.2004.05.026

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 26894959

Title: Binary architecture of the Nav1.2-beta2 signaling complex.

PubMed ID: 26894959

DOI: 10.7554/elife.10960

Sequence Information:

  • Length: 215
  • Mass: 24145
  • Checksum: 23D432EA83C1459D
  • Sequence:
    • MHRDAWLPRP AFSLTGLSLF FSLVPSGRSM EVTVPTTLSV LNGSDTRLPC TFNSCYTVNH 
KQFSLNWTYQ ECSNCSEEMF LQFRMKIINL KLERFGDRVE FSGNPSKYDV SVTLKNVQLE 
DEGIYNCYIT NPPDRHRGHG KIYLQVLLEV PPERDSTVAV IVGASVGGFL AVVILVLMVV 
KCVRRKKEQK LSTDDLKTEE EGKTDGEGNA EDGAK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.