Spp1 | ENSRNOG00000043451 | NCBI 25353

Details for: Spp1

Gene ID: 25353

Symbol: Spp1

Ensembl ID: ENSRNOG00000043451

Description: secreted phosphoprotein 1

Associated with

Degradation of the extracellular matrix
(R-RNO-1474228)
Extracellular matrix organization
(R-RNO-1474244)
Integrin cell surface interactions
(R-RNO-216083)
Metabolism of proteins
(R-RNO-392499)
Post-translational protein modification
(R-RNO-597592)
Post-translational protein phosphorylation
(R-RNO-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-RNO-381426)
Signaling by pdgf
(R-RNO-186797)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Androgen catabolic process
(GO:0006710)
Apical part of cell
(GO:0045177)
Bone mineralization
(GO:0030282)
Calcium ion homeostasis
(GO:0055074)
Cell adhesion
(GO:0007155)
Cell differentiation
(GO:0030154)
Cell projection
(GO:0042995)
Cellular response to fluid shear stress
(GO:0071498)
Cellular response to leukemia inhibitory factor
(GO:1990830)
Cellular response to testosterone stimulus
(GO:0071394)
Collecting duct development
(GO:0072044)
Cytokine activity
(GO:0005125)
Cytoplasm
(GO:0005737)
Extracellular matrix binding
(GO:0050840)
Extracellular space
(GO:0005615)
Golgi apparatus
(GO:0005794)
Integrin binding
(GO:0005178)
Intracellular calcium ion homeostasis
(GO:0006874)
Intracellular chloride ion homeostasis
(GO:0030644)
Intracellular phosphate ion homeostasis
(GO:0030643)
Intracellular sodium ion homeostasis
(GO:0006883)
Ion binding
(GO:0043167)
Negative regulation of collateral sprouting of intact axon in response to injury
(GO:0048685)
Neutrophil chemotaxis
(GO:0030593)
Ossification
(GO:0001503)
Osteoblast differentiation
(GO:0001649)
Perinuclear region of cytoplasm
(GO:0048471)
Positive regulation of bone resorption
(GO:0045780)
Positive regulation of cell-substrate adhesion
(GO:0010811)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of estradiol secretion
(GO:2000866)
Response to macrophage colony-stimulating factor
(GO:0036005)
Response to organic substance
(GO:0010033)
Response to steroid hormone
(GO:0048545)
Response to vitamin d
(GO:0033280)
Signal transduction
(GO:0007165)
Small molecule binding
(GO:0036094)
Urate biosynthetic process
(GO:0034418)
Vesicle
(GO:0031982)

Other Information

Proteins

Osteopontin

Genular Protein ID: 1776349512

Symbol: OSTP_RAT

Name: Osteopontin

UniProtKB Accession Codes:

P08721

Database IDs:

Citations:

PubMed ID: 1429723

Title: Differential processing of osteopontin transcripts in rat kidney- and osteoblast-derived cell lines.

PubMed ID: 1429723

DOI: 10.1016/s0021-9258(18)35914-3

PubMed ID: 3024151

Title: Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence.

PubMed ID: 3024151

DOI: 10.1073/pnas.83.23.8819

PubMed ID: 8408622

Title: Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques.

PubMed ID: 8408622

DOI: 10.1172/jci116755

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2736258

Title: Purification of a human milk protein closely similar to tumor-secreted phosphoproteins and osteopontin.

PubMed ID: 2736258

DOI: 10.1016/0167-4838(89)90092-7

PubMed ID: 3469201

Title: Isolation, characterization, and biosynthesis of a phosphorylated glycoprotein from rat bone.

PubMed ID: 3469201

DOI: 10.1016/s0021-9258(18)61592-3

PubMed ID: 3167835

Title: Secreted phosphoproteins associated with neoplastic transformation: close homology with plasma proteins cleaved during blood coagulation.

PubMed ID: 3167835

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 317
Mass: 34963
Checksum: 73CB5C21FFF62310
Sequence:

MRLAVVCFCL FGLASCLPVK VAEFGSSEEK AHYSKHSDAV ATWLKPDPSQ KQNLLAPQNS 
VSSEETDDFK QETLPSNSNE SHDHMDDDDD DDDDGDHAES EDSVNSDESD ESHHSDESDE 
SFTASTQADV LTPIAPTVDV PDGRGDSLAY GLRSKSRSFP VSDEQYPDAT DEDLTSRMKS 
QESDEAIKVI PVAQRLSVPS DQDSNGKTSH ESSQLDEPSV ETHSLEQSKE YKQRASHEST 
EQSDAIDSAE KPDAIDSAER SDAIDSQASS KASLEHQSHE FHSHEDKLVL DPKSKEDDRY 
LKFRISHELE SSSSEVN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Spp1

Associated with

Other Information

Differential processing of osteopontin transcripts in rat kidney- and osteoblast-derived cell lines. PubMed ID: 1429723

Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence. PubMed ID: 3024151

Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. PubMed ID: 8408622

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Purification of a human milk protein closely similar to tumor-secreted phosphoproteins and osteopontin. PubMed ID: 2736258

Isolation, characterization, and biosynthesis of a phosphorylated glycoprotein from rat bone. PubMed ID: 3469201

Secreted phosphoproteins associated with neoplastic transformation: close homology with plasma proteins cleaved during blood coagulation. PubMed ID: 3167835

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903