Adora2a | ENSRNOG00000001302 | NCBI 25369

Details for: Adora2a

Gene ID: 25369

Symbol: Adora2a

Ensembl ID: ENSRNOG00000001302

Description: adenosine A2a receptor

Associated with

Adenosine p1 receptors
(R-RNO-417973)
Class a/1 (rhodopsin-like receptors)
(R-RNO-373076)
Gpcr ligand binding
(R-RNO-500792)
Metabolism of proteins
(R-RNO-392499)
Nucleotide-like (purinergic) receptors
(R-RNO-418038)
Signaling by gpcr
(R-RNO-372790)
Signal transduction
(R-RNO-162582)
Surfactant metabolism
(R-RNO-5683826)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Alpha-actinin binding
(GO:0051393)
Apoptotic signaling pathway
(GO:0097190)
Astrocyte activation
(GO:0048143)
Asymmetric synapse
(GO:0032279)
Axolemma
(GO:0030673)
Axon
(GO:0030424)
Calmodulin binding
(GO:0005516)
Dendrite
(GO:0030425)
Eating behavior
(GO:0042755)
Enzyme binding
(GO:0019899)
Excitatory postsynaptic potential
(GO:0060079)
Glutamatergic synapse
(GO:0098978)
Golgi membrane
(GO:0000139)
G protein-coupled adenosine receptor activity
(GO:0001609)
G protein-coupled adenosine receptor signaling pathway
(GO:0001973)
G protein-coupled receptor signaling pathway
(GO:0007186)
Identical protein binding
(GO:0042802)
Inhibitory postsynaptic potential
(GO:0060080)
Intermediate filament
(GO:0005882)
Lipid binding
(GO:0008289)
Locomotory behavior
(GO:0007626)
Membrane
(GO:0016020)
Membrane depolarization
(GO:0051899)
Negative regulation of alpha-beta t cell activation
(GO:0046636)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of inflammatory response
(GO:0050728)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of vascular permeability
(GO:0043116)
Neuronal cell body
(GO:0043025)
Neuron projection morphogenesis
(GO:0048812)
Plasma membrane
(GO:0005886)
Positive regulation of acetylcholine secretion, neurotransmission
(GO:0014057)
Positive regulation of apoptotic signaling pathway
(GO:2001235)
Positive regulation of circadian sleep/wake cycle, sleep
(GO:0045938)
Positive regulation of glutamate secretion
(GO:0014049)
Positive regulation of long-term synaptic potentiation
(GO:1900273)
Positive regulation of protein secretion
(GO:0050714)
Positive regulation of synaptic transmission, gabaergic
(GO:0032230)
Positive regulation of synaptic transmission, glutamatergic
(GO:0051968)
Positive regulation of urine volume
(GO:0035810)
Postsynaptic membrane
(GO:0045211)
Prepulse inhibition
(GO:0060134)
Presynaptic active zone
(GO:0048786)
Presynaptic membrane
(GO:0042734)
Presynaptic modulation of chemical synaptic transmission
(GO:0099171)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein kinase c-activating g protein-coupled receptor signaling pathway
(GO:0007205)
Regulation of calcium ion transport
(GO:0051924)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of mitochondrial membrane potential
(GO:0051881)
Regulation of norepinephrine secretion
(GO:0014061)
Response to alkaloid
(GO:0043279)
Response to amphetamine
(GO:0001975)
Response to caffeine
(GO:0031000)
Response to inorganic substance
(GO:0010035)
Response to purine-containing compound
(GO:0014074)
Response to xenobiotic stimulus
(GO:0009410)
Synaptic transmission, cholinergic
(GO:0007271)
Synaptic transmission, dopaminergic
(GO:0001963)
Synaptic transmission, glutamatergic
(GO:0035249)
Type 5 metabotropic glutamate receptor binding
(GO:0031802)
Vasodilation
(GO:0042311)

Other Information

Proteins

Adenosine receptor A2a

Genular Protein ID: 4091679893

Symbol: AA2AR_RAT

Name: Adenosine receptor A2a

UniProtKB Accession Codes:

P30543

Database IDs:

Citations:

PubMed ID: 1599465

Title: Molecular cloning of a novel adenosine receptor gene from rat brain.

PubMed ID: 1599465

DOI: 10.1016/s0006-291x(05)90000-4

PubMed ID: 1279342

Title: Molecular cloning of the rat A2 adenosine receptor: selective co-expression with D2 dopamine receptors in rat striatum.

PubMed ID: 1279342

DOI: 10.1016/0169-328x(92)90173-9

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16339847

Title: The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2A receptor.

PubMed ID: 16339847

DOI: 10.1124/mol.105.015818

PubMed ID: 23994616

Title: A novel Galphas-binding protein, Gas-2 like 2, facilitates the signaling of the A2A adenosine receptor.

PubMed ID: 23994616

DOI: 10.1016/j.bbamcr.2013.08.009

Sequence Information:

Length: 410
Mass: 44999
Checksum: D87B256CD2336BAC
Sequence:

MGSSVYITVE LAIAVLAILG NVLVCWAVWI NSNLQNVTNF FVVSLAAADI AVGVLAIPFA 
ITISTGFCAA CHGCLFFACF VLVLTQSSIF SLLAIAIDRY IAIRIPLRYN GLVTGVRAKG 
IIAICWVLSF AIGLTPMLGW NNCSQKDGNS TKTCGEGRVT CLFEDVVPMN YMVYYNFFAF 
VLLPLLLMLA IYLRIFLAAR RQLKQMESQP LPGERTRSTL QKEVHAAKSL AIIVGLFALC 
WLPLHIINCF TFFCSTCRHA PPWLMYLAII LSHSNSVVNP FIYAYRIREF RQTFRKIIRT 
HVLRRQEPFQ AGGSSAWALA AHSTEGEQVS LRLNGHPLGV WANGSATHSG RRPNGYTLGL 
GGGGSAQGSP RDVELPTQER QEGQEHPGLR GHLVQARVGA SSWSSEFAPS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Adora2a

Associated with

Other Information

Molecular cloning of a novel adenosine receptor gene from rat brain. PubMed ID: 1599465

Molecular cloning of the rat A2 adenosine receptor: selective co-expression with D2 dopamine receptors in rat striatum. PubMed ID: 1279342

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334