Casp3 | ENSRNOG00000010475 | NCBI 25402

Details for: Casp3

Gene ID: 25402

Symbol: Casp3

Ensembl ID: ENSRNOG00000010475

Description: caspase 3

Associated with

Activation of caspases through apoptosome-mediated cleavage
(R-RNO-111459)
Apoptosis
(R-RNO-109581)
Apoptosis induced dna fragmentation
(R-RNO-140342)
Apoptotic cleavage of cell adhesion proteins
(R-RNO-351906)
Apoptotic cleavage of cellular proteins
(R-RNO-111465)
Apoptotic execution phase
(R-RNO-75153)
Apoptotic factor-mediated response
(R-RNO-111471)
Caspase-mediated cleavage of cytoskeletal proteins
(R-RNO-264870)
Caspase activation via dependence receptors in the absence of ligand
(R-RNO-418889)
Caspase activation via extrinsic apoptotic signalling pathway
(R-RNO-5357769)
Cell death signalling via nrage, nrif and nade
(R-RNO-204998)
Cytochrome c-mediated apoptotic response
(R-RNO-111461)
Cytokine signaling in immune system
(R-RNO-1280215)
Death receptor signaling
(R-RNO-73887)
Immune system
(R-RNO-168256)
Intrinsic pathway for apoptosis
(R-RNO-109606)
Nade modulates death signalling
(R-RNO-205025)
Other interleukin signaling
(R-RNO-449836)
P75 ntr receptor-mediated signalling
(R-RNO-193704)
Programmed cell death
(R-RNO-5357801)
Pyroptosis
(R-RNO-5620971)
Regulated necrosis
(R-RNO-5218859)
Signaling by hippo
(R-RNO-2028269)
Signaling by interleukins
(R-RNO-449147)
Signal transduction
(R-RNO-162582)
Smac, xiap-regulated apoptotic response
(R-RNO-111469)
Anterior neural tube closure
(GO:0061713)
Apoptotic process
(GO:0006915)
Aspartic-type endopeptidase activity
(GO:0004190)
Axonal fasciculation
(GO:0007413)
B cell homeostasis
(GO:0001782)
Cell fate commitment
(GO:0045165)
Cyclin-dependent protein serine/threonine kinase inhibitor activity
(GO:0004861)
Cysteine-type endopeptidase activity
(GO:0004197)
Cysteine-type endopeptidase activity involved in apoptotic process
(GO:0097153)
Cysteine-type endopeptidase activity involved in apoptotic signaling pathway
(GO:0097199)
Cysteine-type endopeptidase activity involved in execution phase of apoptosis
(GO:0097200)
Cysteine-type peptidase activity
(GO:0008234)
Death receptor binding
(GO:0005123)
Dna damage response
(GO:0006974)
Endopeptidase activity
(GO:0004175)
Enzyme activator activity
(GO:0008047)
Erythrocyte differentiation
(GO:0030218)
Fibroblast apoptotic process
(GO:0044346)
Glial cell apoptotic process
(GO:0034349)
Heart development
(GO:0007507)
Hippocampus development
(GO:0021766)
Intracellular signal transduction
(GO:0035556)
Intrinsic apoptotic signaling pathway in response to osmotic stress
(GO:0008627)
Keratinocyte differentiation
(GO:0030216)
Learning or memory
(GO:0007611)
Luteolysis
(GO:0001554)
Negative regulation of activated t cell proliferation
(GO:0046007)
Negative regulation of b cell proliferation
(GO:0030889)
Negative regulation of cell cycle
(GO:0045786)
Negative regulation of cytokine production
(GO:0001818)
Neuron apoptotic process
(GO:0051402)
Neuron differentiation
(GO:0030182)
Neurotrophin trk receptor signaling pathway
(GO:0048011)
Peptidase activity
(GO:0008233)
Phospholipase a2 activator activity
(GO:0016005)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of neuron apoptotic process
(GO:0043525)
Protease binding
(GO:0002020)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein catabolic process
(GO:0030163)
Protein maturation
(GO:0051604)
Protein processing
(GO:0016485)
Proteolysis
(GO:0006508)
Regulation of protein stability
(GO:0031647)
Response to amino acid
(GO:0043200)
Response to auditory stimulus
(GO:0010996)
Response to cobalt ion
(GO:0032025)
Response to estradiol
(GO:0032355)
Response to glucocorticoid
(GO:0051384)
Response to glucose
(GO:0009749)
Response to hydrogen peroxide
(GO:0042542)
Response to hypoxia
(GO:0001666)
Response to lipopolysaccharide
(GO:0032496)
Response to metal ion
(GO:0010038)
Response to nicotine
(GO:0035094)
Response to organic cyclic compound
(GO:0014070)
Response to organic substance
(GO:0010033)
Response to uv
(GO:0009411)
Response to wounding
(GO:0009611)
Response to x-ray
(GO:0010165)
Response to xenobiotic stimulus
(GO:0009410)
Sensory perception of sound
(GO:0007605)
Striated muscle cell differentiation
(GO:0051146)
T cell homeostasis
(GO:0043029)

Other Information

Proteins

Caspase-3

Genular Protein ID: 4059069970

Symbol: CASP3_RAT

Name: Caspase-3

UniProtKB Accession Codes:

P55213 P70543 P97699 Q62993

Database IDs:

Citations:

PubMed ID: 8761296

Title: Molecular characterization of mouse and rat CPP32 beta gene encoding a cysteine protease resembling interleukin-1 beta converting enzyme and CED-3.

PubMed ID: 8761296

PubMed ID: 9030616

Title: Cloning and expression of a rat brain interleukin-1beta-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons.

PubMed ID: 9030616

DOI: 10.1523/jneurosci.17-05-01561.1997

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7588240

Title: Interleukin-1 beta-converting enzyme-related proteases (IRPs) and mammalian cell death: dissociation of IRP-induced oligonucleosomal endonuclease activity from morphological apoptosis in granulosa cells of the ovarian follicle.

PubMed ID: 7588240

DOI: 10.1210/endo.136.11.7588240

Sequence Information:

Length: 277
Mass: 31492
Checksum: ADABF418E2507402
Sequence:

MDNNETSVDS KSINNFETKT IHGSKSMDSG IYLDSSYKMD YPEMGLCIII NNKNFHKSTG 
MSARNGTDVD AANLRETFMA LKYEVRNKND LTREEIMELM DSVSKEDHSK RSSFVCVILS 
HGDEGVIFGT NGPVDLKKLT SFFRGDYCRS LTGKPKLFII QACRGTELDC GIETDSGTDD 
DMACQKIPVE ADFLYAYSTA PGYYSWRNSR DGSWFIQSLC AMLKLYAHKL EFMHILTRVN 
RKVATEFESF SLDATFHAKK QIPCIVSMLT KELYFYH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Casp3

Associated with

Other Information

Molecular characterization of mouse and rat CPP32 beta gene encoding a cysteine protease resembling interleukin-1 beta converting enzyme and CED-3. PubMed ID: 8761296

Cloning and expression of a rat brain interleukin-1beta-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons. PubMed ID: 9030616

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Interleukin-1 beta-converting enzyme-related proteases (IRPs) and mammalian cell death: dissociation of IRP-induced oligonucleosomal endonuclease activity from morphological apoptosis in granulosa cells of the ovarian follicle. PubMed ID: 7588240

Database document:

PubMed ID: 8761296

PubMed ID: 9030616

PubMed ID: 15489334

PubMed ID: 7588240