Cyp7b1 | ENSRNOG00000009730 | NCBI 25429

Details for: Cyp7b1

Gene ID: 25429

Symbol: Cyp7b1

Ensembl ID: ENSRNOG00000009730

Description: cytochrome P450 family 7 subfamily B member 1

Associated with

Bile acid and bile salt metabolism
(R-RNO-194068)
Biological oxidations
(R-RNO-211859)
Cytochrome p450 - arranged by substrate type
(R-RNO-211897)
Endogenous sterols
(R-RNO-211976)
Metabolism
(R-RNO-1430728)
Metabolism of lipids
(R-RNO-556833)
Metabolism of steroids
(R-RNO-8957322)
Phase i - functionalization of compounds
(R-RNO-211945)
Synthesis of bile acids and bile salts
(R-RNO-192105)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
(R-RNO-193368)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol
(R-RNO-193807)
25-hydroxycholesterol 7alpha-hydroxylase activity
(GO:0033783)
27-hydroxycholesterol 7-alpha-monooxygenase activity
(GO:0047092)
B cell chemotaxis
(GO:0035754)
Bile acid biosynthetic process
(GO:0006699)
Cholesterol homeostasis
(GO:0042632)
Cholesterol metabolic process
(GO:0008203)
Circadian rhythm
(GO:0007623)
Endoplasmic reticulum membrane
(GO:0005789)
Epithelial cell proliferation
(GO:0050673)
Heme binding
(GO:0020037)
Intracellular estrogen receptor signaling pathway
(GO:0030520)
Iron ion binding
(GO:0005506)
Memory
(GO:0007613)
Monooxygenase activity
(GO:0004497)
Negative regulation of intracellular estrogen receptor signaling pathway
(GO:0033147)
Organic hydroxy compound metabolic process
(GO:1901615)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
(GO:0016705)
Oxysterol 7-alpha-hydroxylase activity
(GO:0008396)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Prostate gland epithelium morphogenesis
(GO:0060740)
Response to camp
(GO:0051591)
Response to xenobiotic stimulus
(GO:0009410)
Small molecule metabolic process
(GO:0044281)
Steroid metabolic process
(GO:0008202)

Other Information

Proteins

25-hydroxycholesterol 7-alpha-hydroxylase

Genular Protein ID: 1731463719

Symbol: CP7B1_RAT

Name: 25-hydroxycholesterol 7-alpha-hydroxylase

UniProtKB Accession Codes:

Q63688

Database IDs:

Citations:

PubMed ID: 8530364

Title: A novel cytochrome P450 expressed primarily in brain.

PubMed ID: 8530364

DOI: 10.1074/jbc.270.50.29739

PubMed ID: 12759897

Title: Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in the rat.

PubMed ID: 12759897

DOI: 10.1053/meta.2003.50106

Sequence Information:

Length: 414
Mass: 48227
Checksum: F2111BF6A1575BD2
Sequence:

ALEYQYVMKN PKQLSFEKFS RRLSAKAFSV KKLLTNDDLS NDIHRGYLLL QGKSLDGLLE 
TMIQEVKEIF ESRLLKLTDW NTARVFDFCS SLVFEITFTT IYGKILAANK KQIISELRDD 
FLKFDDHFPY LVSDIPIQLL RNAEFMQKKI IKCLTPEKVA QMQRRSEIVQ ERQEMLKKYY 
GHEEFEIGAH HLGLLWASLA NTIPAMFWAM YYLLQHPEAM EVLRDEIDSF LQSTGQKKGP 
GISVHFTREQ LDSLVCLESA ILEVLRLCSY SSIIREVQED MDFSSESRSY RLRKGDFVAV 
FPPMIHNDPE VFDAPKDFRF DRFVEDGKKK TTFFKGGKKL KSYIIPFGLG TSKCPGRYFA 
INEMKLLVII LLTYFDLEVI DTKPIGLNHS RMFLGIQHPD SDISFRYKAK SWRS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.