Details for: F2r

Gene ID: 25439

Symbol: F2r

Ensembl ID: ENSRNOG00000048043

Description: coagulation factor II (thrombin) receptor

Associated with

  • Class a/1 (rhodopsin-like receptors)
    (R-RNO-373076)
  • Common pathway of fibrin clot formation
    (R-RNO-140875)
  • Formation of fibrin clot (clotting cascade)
    (R-RNO-140877)
  • G alpha (q) signalling events
    (R-RNO-416476)
  • Gpcr downstream signalling
    (R-RNO-388396)
  • Gpcr ligand binding
    (R-RNO-500792)
  • Hemostasis
    (R-RNO-109582)
  • Peptide ligand-binding receptors
    (R-RNO-375276)
  • Platelet activation, signaling and aggregation
    (R-RNO-76002)
  • Signaling by gpcr
    (R-RNO-372790)
  • Signal transduction
    (R-RNO-162582)
  • Thrombin signalling through proteinase activated receptors (pars)
    (R-RNO-456926)
  • Caveola
    (GO:0005901)
  • Cell-cell junction maintenance
    (GO:0045217)
  • Cell surface
    (GO:0009986)
  • Connective tissue replacement involved in inflammatory response wound healing
    (GO:0002248)
  • Dendritic cell homeostasis
    (GO:0036145)
  • Early endosome
    (GO:0005769)
  • Establishment of synaptic specificity at neuromuscular junction
    (GO:0007529)
  • G-protein alpha-subunit binding
    (GO:0001965)
  • G-protein beta-subunit binding
    (GO:0031681)
  • G protein-coupled receptor activity
    (GO:0004930)
  • G protein-coupled receptor signaling pathway
    (GO:0007186)
  • Homeostasis of number of cells within a tissue
    (GO:0048873)
  • Inflammatory response
    (GO:0006954)
  • Late endosome
    (GO:0005770)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of glomerular filtration
    (GO:0003105)
  • Negative regulation of neuron apoptotic process
    (GO:0043524)
  • Negative regulation of renin secretion into blood stream
    (GO:1900134)
  • Neuromuscular junction
    (GO:0031594)
  • Phospholipase c-activating g protein-coupled receptor signaling pathway
    (GO:0007200)
  • Plasma membrane
    (GO:0005886)
  • Platelet activation
    (GO:0030168)
  • Platelet dense tubular network
    (GO:0031094)
  • Positive regulation of blood coagulation
    (GO:0030194)
  • Positive regulation of calcium ion transport
    (GO:0051928)
  • Positive regulation of canonical nf-kappab signal transduction
    (GO:0043123)
  • Positive regulation of cell migration
    (GO:0030335)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of collagen biosynthetic process
    (GO:0032967)
  • Positive regulation of cytosolic calcium ion concentration
    (GO:0007204)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of erk1 and erk2 cascade
    (GO:0070374)
  • Positive regulation of interleukin-6 production
    (GO:0032755)
  • Positive regulation of interleukin-8 production
    (GO:0032757)
  • Positive regulation of mapk cascade
    (GO:0043410)
  • Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051897)
  • Positive regulation of receptor signaling pathway via jak-stat
    (GO:0046427)
  • Positive regulation of release of sequestered calcium ion into cytosol
    (GO:0051281)
  • Positive regulation of rho protein signal transduction
    (GO:0035025)
  • Positive regulation of smooth muscle contraction
    (GO:0045987)
  • Positive regulation of vasoconstriction
    (GO:0045907)
  • Postsynaptic membrane
    (GO:0045211)
  • Protein kinase c-activating g protein-coupled receptor signaling pathway
    (GO:0007205)
  • Regulation of blood coagulation
    (GO:0030193)
  • Regulation of interleukin-1 beta production
    (GO:0032651)
  • Release of sequestered calcium ion into cytosol
    (GO:0051209)
  • Response to lipopolysaccharide
    (GO:0032496)
  • Response to wounding
    (GO:0009611)
  • Signaling receptor binding
    (GO:0005102)
  • Synapse
    (GO:0045202)
  • Thrombin-activated receptor activity
    (GO:0015057)
  • Thrombin-activated receptor signaling pathway
    (GO:0070493)
  • Trans-synaptic signaling by endocannabinoid, modulating synaptic transmission
    (GO:0099553)

Other Information

Genular Protein ID: 74428637

Symbol: A0A9K3Y7Y4_RAT

Name: N/A

UniProtKB Accession Codes:

A0A9K3Y7Y4

Database IDs:

ARBA 15 CDD 1 CTD 1 EMBL 4 GO 3 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 3 PROSITE 3 Pfam 1 Proteomes 1 RGD 2 RefSeq 1 RuleBase 1 SAM 2 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

  • Length: 432
  • Mass: 48343
  • Checksum: 360447E604CD02CF
  • Sequence:
    • MGPRRLLLVA VGLSLCGPLL SSRVPMRQPE SERMYATPYA TPNPRSFFLR NPSEDTFEQF 
PLGDEEEKNE SIPLEGRAVY LNKSRFPPMP PPPFISEDAS GYLTSPWLTL FIPSVYTFVF 
IVSLPLNILA IAVFVFRMKV KKPAVVYMLH LAMADVLFVS VLPFKISYYF SGTDWQFGSG 
MCRFATAAFY CNMYASIMLM TVISIDRFLA VVYPIQSLSW RTLGRANFTC VVIWVMAIMG 
VVPLLLKEQT TQVPGLNITT CHDVLNETLL HGFYSYYFSA FSAIFFLVPL IISTVCYTSI 
IRCLSSSAVA NRSKKSRALF LSAAVFCIFI VCFGPTNVLL IVHYLLLSDS PGTETAYFAY 
LLCVCVSSVS CCIDPLIYYY ASSECQKHLY SILCCRESSD SNSCNSTGQL MPSKMDTCSS 
HLNNSIYKKL LA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.