Details for: Gfra1

Gene ID: 25454

Symbol: Gfra1

Ensembl ID: ENSRNOG00000017438

Description: GDNF family receptor alpha 1

Associated with

Other Information

Genular Protein ID: 2508653529

Symbol: GFRA1_RAT

Name: GDNF family receptor alpha-1

UniProtKB Accession Codes:

Q62997

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID 1 CTD 1 EMBL 2 EMDB 1 Ensembl 4 EvolutionaryTrace 1 GO 19 Gene3D 1 GeneTree 1 GlyCosmos 1 GlyGen 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 4 PIRSF 1 PRINTS 2 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 2 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UniProtKB 1 eggNOG 1

Citations:

PubMed ID: 8674117

Title: GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF.

PubMed ID: 8674117

DOI: 10.1016/s0092-8674(00)81311-2

PubMed ID: 9177201

Title: Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins.

PubMed ID: 9177201

DOI: 10.1073/pnas.94.12.6238

PubMed ID: 8657309

Title: Characterization of a multicomponent receptor for GDNF.

PubMed ID: 8657309

DOI: 10.1038/382080a0

PubMed ID: 10719212

Title: Expression of the GDNF family members and their receptors in the mature rat cochlea.

PubMed ID: 10719212

DOI: 10.1016/s0169-328x(99)00328-9

PubMed ID: 23333276

Title: SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRalpha1 and RET.

PubMed ID: 23333276

DOI: 10.1016/j.celrep.2012.12.011

PubMed ID: 15044950

Title: The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation.

PubMed ID: 15044950

DOI: 10.1038/sj.emboj.7600174

Sequence Information:

  • Length: 468
  • Mass: 51650
  • Checksum: B2EE5906F5025E0F
  • Sequence:
    • MFLATLYFAL PLLDLLMSAE VSGGDRLDCV KASDQCLKEQ SCSTKYRTLR QCVAGKETNF 
SLTSGLEAKD ECRSAMEALK QKSLYNCRCK RGMKKEKNCL RIYWSMYQSL QGNDLLEDSP 
YEPVNSRLSD IFRAVPFISD VFQQVEHISK GNNCLDAAKA CNLDDTCKKY RSAYITPCTT 
SMSNEVCNRR KCHKALRQFF DKVPAKHSYG MLFCSCRDIA CTERRRQTIV PVCSYEERER 
PNCLSLQDSC KTNYICRSRL ADFFTNCQPE SRSVSNCLKE NYADCLLAYS GLIGTVMTPN 
YVDSSSLSVA PWCDCSNSGN DLEDCLKFLN FFKDNTCLKN AIQAFGNGSD VTMWQPAPPV 
QTTTATTTTA FRVKNKPLGP AGSENEIPTH VLPPCANLQA QKLKSNVSGS THLCLSDSDF 
GKDGLAGASS HITTKSMAAP PSCSLSSLPV LMLTALAALL SVSLAETS

Genular Protein ID: 1826204931

Symbol: A6JI56_RAT

Name: N/A

UniProtKB Accession Codes:

A6JI56

Database IDs:

ARBA 10 CTD 1 EMBL 4 GO 4 Gene3D 1 InterPro 5 NCBI Taxonomy 1 PANTHER 2 PIRNR 1 PIRSF 1 PRINTS 2 Pfam 1 Proteomes 1 RefSeq 1 SMART 2 SUPFAM 1

Citations:

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

  • Length: 463
  • Mass: 51032
  • Checksum: CCC9583ACE7353CA
  • Sequence:
    • MFLATLYFAL PLLDLLMSAE VSGGDRLDCV KASDQCLKEQ SCSTKYRTLR QCVAGKETNF 
SLTSGLEAKD ECRSAMEALK QKSLYNCRCK RGMKKEKNCL RIYWSMYQSL QGNDLLEDSP 
YEPVNSRLSD IFRAVPFISV EHISKGNNCL DAAKACNLDD TCKKYRSAYI TPCTTSMSNE 
VCNRRKCHKA LRQFFDKVPA KHSYGMLFCS CRDIACTERR RQTIVPVCSY EERERPNCLS 
LQDSCKTNYI CRSRLADFFT NCQPESRSVS NCLKENYADC LLAYSGLIGT VMTPNYVDSS 
SLSVAPWCDC SNSGNDLEDC LKFLNFFKDN TCLKNAIQAF GNGSDVTMWQ PAPPVQTTTA 
TTTTAFRVKN KPLGPAGSEN EIPTHVLPPC ANLQAQKLKS NVSGSTHLCL SDSDFGKDGL 
AGASSHITTK SMAAPPSCSL SSLPVLMLTA LAALLSVSLA ETS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.