Associated with
Other Information
Genular Protein ID: 279053670
Symbol: HMGB1_RAT
Name: High mobility group protein B1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3684582
PubMed ID: 1885601
Title: 30-kDa heparin-binding protein of brain (amphoterin) involved in neurite outgrowth. Amino acid sequence and localization in the filopodia of the advancing plasma membrane.
PubMed ID: 1885601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2461949
Title: The adhesive and neurite-promoting molecule p30: analysis of the amino-terminal sequence and production of antipeptide antibodies that detect p30 at the surface of neuroblastoma cells and of brain neurons.
PubMed ID: 2461949
PubMed ID: 2922595
Title: Specific recognition of cruciform DNA by nuclear protein HMG1.
PubMed ID: 2922595
PubMed ID: 7592757
Title: The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system.
PubMed ID: 7592757
PubMed ID: 9507007
Title: High affinity binding and overlapping localization of neurocan and phosphacan/protein-tyrosine phosphatase-zeta/beta with tenascin-R, amphoterin, and the heparin-binding growth-associated molecule.
PubMed ID: 9507007
PubMed ID: 10866811
Title: HMG1 protein stimulates DNA end joining by promoting association of DNA molecules via their ends.
PubMed ID: 10866811
PubMed ID: 10952726
Title: High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes.
PubMed ID: 10952726
PubMed ID: 10830965
Title: Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases.
PubMed ID: 10830965
DOI: 10.1038/35012626
PubMed ID: 11154118
Title: Occurrence of amphoterin (HMG1) as an endogenous protein of human platelets that is exported to the cell surface upon platelet activation.
PubMed ID: 11154118
PubMed ID: 11513603
Title: Thermodynamics of HMGB1 interaction with duplex DNA.
PubMed ID: 11513603
DOI: 10.1021/bi0100900
PubMed ID: 12183440
Title: Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis.
PubMed ID: 12183440
PubMed ID: 12486007
Title: The DNA chaperone HMGB1 facilitates ACF/CHRAC-dependent nucleosome sliding.
PubMed ID: 12486007
DOI: 10.1093/emboj/cdf692
PubMed ID: 12110890
Title: Release of chromatin protein HMGB1 by necrotic cells triggers inflammation.
PubMed ID: 12110890
DOI: 10.1038/nature00858
PubMed ID: 14532127
Title: Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion.
PubMed ID: 14532127
DOI: 10.1093/emboj/cdg516
PubMed ID: 15379539
Title: The long acidic tail of high mobility group box 1 (HMGB1) protein forms an extended and flexible structure that interacts with specific residues within and between the HMG boxes.
PubMed ID: 15379539
DOI: 10.1021/bi049364k
PubMed ID: 15808513
Title: GR and HMGB1 interact only within chromatin and influence each other's residence time.
PubMed ID: 15808513
PubMed ID: 16962095
Title: Molecular basis for the redox control of nuclear transport of the structural chromatin protein Hmgb1.
PubMed ID: 16962095
PubMed ID: 17269659
Title: DNA bending versus DNA end joining activity of HMGB1 protein is modulated in vitro by acetylation.
PubMed ID: 17269659
DOI: 10.1021/bi0614479
PubMed ID: 18277947
Title: Relationship between high-mobility group box 1 protein release and T-cell suppression in rats after thermal injury.
PubMed ID: 18277947
PubMed ID: 20819940
PubMed ID: 20547845
Title: A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release.
PubMed ID: 20547845
PubMed ID: 22869893
Title: Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release.
PubMed ID: 22869893
DOI: 10.1084/jem.20120189
PubMed ID: 22105604
Title: Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1).
PubMed ID: 22105604
PubMed ID: 33380312
Title: Retraction Note to: Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1).
PubMed ID: 33380312
PubMed ID: 23519706
Title: HMGB1: The central cytokine for all lymphoid cells.
PubMed ID: 23519706
PubMed ID: 23446148
Title: The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis.
PubMed ID: 23446148
DOI: 10.1189/jlb.1212662
PubMed ID: 23508573
Title: Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14.
PubMed ID: 23508573
PubMed ID: 23994764
Title: Menage a Trois in stress: DAMPs, redox and autophagy.
PubMed ID: 23994764
PubMed ID: 24551219
Title: Binding of histone H1 to DNA is differentially modulated by redox state of HMGB1.
PubMed ID: 24551219
PubMed ID: 25048472
Title: The role of high mobility group box 1 in innate immunity.
PubMed ID: 25048472
PubMed ID: 8467791
Title: Structure of the HMG box motif in the B-domain of HMG1.
PubMed ID: 8467791
PubMed ID: 8527432
Title: Structure of the A-domain of HMG1 and its interaction with DNA as studied by heteronuclear three- and four-dimensional NMR spectroscopy.
PubMed ID: 8527432
DOI: 10.1021/bi00051a007
Sequence Information:
- Length: 215
- Mass: 24894
- Checksum: 8A868DE266D552B5
- Sequence:
MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK DPNAPKRPPS AFFLFCSEYR PKIKGEHPGL SIGDVAKKLG EMWNNTAADD KQPYEKKAAK LKEKYEKDIA AYRAKGKPDA AKKGVVKAEK SKKKKEEEDD EEDEEDEEEE EEEEDEDEEE DDDDE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.