Kcna5 | ENSRNOG00000019719 | NCBI 25470

Details for: Kcna5

Gene ID: 25470

Symbol: Kcna5

Ensembl ID: ENSRNOG00000019719

Description: potassium voltage-gated channel subfamily A member 5

Associated with

Cardiac conduction
(R-RNO-5576891)
Muscle contraction
(R-RNO-397014)
Neuronal system
(R-RNO-112316)
Phase 3 - rapid repolarisation
(R-RNO-5576890)
Potassium channels
(R-RNO-1296071)
Voltage gated potassium channels
(R-RNO-1296072)
Alpha-actinin binding
(GO:0051393)
Atrial cardiac muscle cell action potential
(GO:0086014)
Cell surface
(GO:0009986)
Delayed rectifier potassium channel activity
(GO:0005251)
Intercalated disc
(GO:0014704)
Intracellular canaliculus
(GO:0046691)
Membrane
(GO:0016020)
Membrane hyperpolarization
(GO:0060081)
Membrane raft
(GO:0045121)
Membrane repolarization during atrial cardiac muscle cell action potential
(GO:0098914)
Membrane repolarization during bundle of his cell action potential
(GO:0086050)
Membrane repolarization during sa node cell action potential
(GO:0086052)
Negative regulation of cytosolic calcium ion concentration
(GO:0051481)
Negative regulation of potassium ion transport
(GO:0043267)
Notch signaling pathway
(GO:0007219)
Outward rectifier potassium channel activity
(GO:0015271)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Positive regulation of g1/s transition of mitotic cell cycle
(GO:1900087)
Positive regulation of myoblast proliferation
(GO:2000288)
Potassium channel complex
(GO:0034705)
Potassium channel inhibitor activity
(GO:0019870)
Potassium ion export across plasma membrane
(GO:0097623)
Potassium ion homeostasis
(GO:0055075)
Potassium ion transmembrane transport
(GO:0071805)
Potassium ion transport
(GO:0006813)
Protein binding
(GO:0005515)
Protein complex oligomerization
(GO:0051259)
Protein homooligomerization
(GO:0051260)
Protein kinase binding
(GO:0019901)
Regulation of atrial cardiac muscle cell membrane repolarization
(GO:0060372)
Regulation of heart rate by cardiac conduction
(GO:0086091)
Regulation of membrane potential
(GO:0042391)
Regulation of potassium ion transport
(GO:0043266)
Regulation of vasoconstriction
(GO:0019229)
Response to hydrogen peroxide
(GO:0042542)
Response to hyperoxia
(GO:0055093)
Response to hypoxia
(GO:0001666)
Response to mechanical stimulus
(GO:0009612)
Response to organic substance
(GO:0010033)
Scaffold protein binding
(GO:0097110)
Signaling receptor binding
(GO:0005102)
Voltage-gated potassium channel activity
(GO:0005249)
Voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
(GO:0086089)
Voltage-gated potassium channel activity involved in bundle of his cell action potential repolarization
(GO:0086087)
Voltage-gated potassium channel activity involved in sa node cell action potential repolarization
(GO:0086090)
Voltage-gated potassium channel complex
(GO:0008076)
Z disc
(GO:0030018)

Other Information

Proteins

Potassium voltage-gated channel subfamily A member 5

Genular Protein ID: 4247407258

Symbol: KCNA5_RAT

Name: Potassium voltage-gated channel subfamily A member 5

UniProtKB Accession Codes:

P19024 Q6LEB7

Database IDs:

Citations:

PubMed ID: 2361015

Title: Cloning and expression of cDNA and genomic clones encoding three delayed rectifier potassium channels in rat brain.

PubMed ID: 2361015

DOI: 10.1016/0896-6273(90)90146-7

PubMed ID: 1705709

Title: Cloning and tissue-specific expression of five voltage-gated potassium channel cDNAs expressed in rat heart.

PubMed ID: 1705709

DOI: 10.1073/pnas.88.5.1798

PubMed ID: 8253777

Title: The transcription of a mammalian voltage-gated potassium channel is regulated by cAMP in a cell-specific manner.

PubMed ID: 8253777

DOI: 10.1016/s0021-9258(19)74340-3

PubMed ID: 11709425

Title: SAP97 interacts with Kv1.5 in heterologous expression systems.

PubMed ID: 11709425

DOI: 10.1152/ajpheart.2001.281.6.h2575

PubMed ID: 15277200

Title: Caveolin-3 and SAP97 form a scaffolding protein complex that regulates the voltage-gated potassium channel Kv1.5.

PubMed ID: 15277200

DOI: 10.1152/ajpheart.00152.2004

PubMed ID: 15618540

Title: Heteromultimeric Kv1 channels contribute to myogenic control of arterial diameter.

PubMed ID: 15618540

DOI: 10.1161/01.res.0000154070.06421.25

Sequence Information:

Length: 602
Mass: 66553
Checksum: 6A784535FF226ED7
Sequence:

MEISLVPLEN GSAMTLRGGG EAGASCVQTP RGECGCPPTS GLNNQSKETL LRGRTTLEDA 
NQGGRPLPPM AQELPQPRRL SAEDEEGEGD PGLGTVEEDQ APQDAGSLHH QRVLINISGL 
RFETQLGTLA QFPNTLLGDP AKRLHYFDPL RNEYFFDRNR PSFDGILYYY QSGGRLRRPV 
NVSLDVFADE IRFYQLGDEA MERFREDEGF IKEEEKPLPR NEFQRQVWLI FEYPESSGSA 
RAIAIVSVLV ILISIITFCL ETLPEFRDER ELLRHPPVPP QPPAPAPGIN GSVSGALSSG 
PTVAPLLPRT LADPFFIVET TCVIWFTFEL LVRFFACPSK AEFSRNIMNI IDVVAIFPYF 
ITLGTELAEQ QPGGGGQNGQ QAMSLAILRV IRLVRVFRIF KLSRHSKGLQ ILGKTLQASM 
RELGLLIFFL FIGVILFSSA VYFAEADNHG SHFSSIPDAF WWAVVTMTTV GYGDMRPITV 
GGKIVGSLCA IAGVLTIALP VPVIVSNFNY FYHRETDHEE QAALKEEQGN QRRESGLDTG 
GQRKVSCSKA SFCKTGGSLE SSDSIRRGSC PLEKCHLKAK SNVDLRRSLY ALCLDTSRET 
DL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Kcna5

Associated with

Other Information

Cloning and expression of cDNA and genomic clones encoding three delayed rectifier potassium channels in rat brain. PubMed ID: 2361015

Cloning and tissue-specific expression of five voltage-gated potassium channel cDNAs expressed in rat heart. PubMed ID: 1705709

The transcription of a mammalian voltage-gated potassium channel is regulated by cAMP in a cell-specific manner. PubMed ID: 8253777

SAP97 interacts with Kv1.5 in heterologous expression systems. PubMed ID: 11709425

Caveolin-3 and SAP97 form a scaffolding protein complex that regulates the voltage-gated potassium channel Kv1.5. PubMed ID: 15277200