Details for: Kcne1

Gene ID: 25471

Symbol: Kcne1

Ensembl ID: ENSRNOG00000001984

Description: potassium voltage-gated channel subfamily E regulatory subunit 1

Associated with

  • Apical plasma membrane
    (GO:0016324)
  • Cardiac muscle cell action potential involved in contraction
    (GO:0086002)
  • Cell surface
    (GO:0009986)
  • Cellular response to acidic ph
    (GO:0071468)
  • Cellular response to camp
    (GO:0071320)
  • Cellular response to light stimulus
    (GO:0071482)
  • Delayed rectifier potassium channel activity
    (GO:0005251)
  • Epithelial cell maturation
    (GO:0002070)
  • Heart contraction
    (GO:0060047)
  • Male gonad development
    (GO:0008584)
  • Membrane raft
    (GO:0045121)
  • Membrane repolarization
    (GO:0086009)
  • Membrane repolarization during action potential
    (GO:0086011)
  • Membrane repolarization during cardiac muscle cell action potential
    (GO:0086013)
  • Membrane repolarization during ventricular cardiac muscle cell action potential
    (GO:0098915)
  • Negative regulation of delayed rectifier potassium channel activity
    (GO:1902260)
  • Negative regulation of protein targeting to membrane
    (GO:0090315)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of potassium ion transmembrane transport
    (GO:1901381)
  • Potassium channel regulator activity
    (GO:0015459)
  • Potassium ion export across plasma membrane
    (GO:0097623)
  • Potassium ion transmembrane transport
    (GO:0071805)
  • Protein-containing complex binding
    (GO:0044877)
  • Protein binding
    (GO:0005515)
  • Regulation of heart rate by cardiac conduction
    (GO:0086091)
  • Regulation of potassium ion transmembrane transport
    (GO:1901379)
  • Regulation of ventricular cardiac muscle cell membrane repolarization
    (GO:0060307)
  • Secretory granule organization
    (GO:0033363)
  • Telethonin binding
    (GO:0031433)
  • Transmembrane transporter binding
    (GO:0044325)
  • Ventricular cardiac muscle cell action potential
    (GO:0086005)
  • Vestibular nucleus development
    (GO:0021750)
  • Voltage-gated potassium channel activity
    (GO:0005249)
  • Voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
    (GO:0086008)
  • Voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
    (GO:1902282)
  • Voltage-gated potassium channel complex
    (GO:0008076)
  • Z disc
    (GO:0030018)

Other Information

Genular Protein ID: 2017168251

Symbol: KCNE1_RAT

Name: Potassium voltage-gated channel subfamily E member 1

UniProtKB Accession Codes:

P15383

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 CORUM 1 CTD 1 EMBL 3 Ensembl 16 GO 34 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 RefSeq 6 SMR 1 STRING 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 2 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 3194754

Title: Cloning of a membrane protein that induces a slow voltage-gated potassium current.

PubMed ID: 3194754

DOI: 10.1126/science.3194754

PubMed ID: 2183220

Title: Cloning and expression of the delayed-rectifier IsK channel from neonatal rat heart and diethylstilbestrol-primed rat uterus.

PubMed ID: 2183220

DOI: 10.1073/pnas.87.8.2975

PubMed ID: 2344412

Title: Estrogen induction of a small, putative K+ channel mRNA in rat uterus.

PubMed ID: 2344412

DOI: 10.1016/0896-6273(90)90207-v

PubMed ID: 2229022

Title: Characterization of gene organization and generation of heterogeneous mRNA species of rat ISK protein.

PubMed ID: 2229022

DOI: 10.1093/oxfordjournals.jbchem.a123181

PubMed ID: 1553557

Title: An amino acid mutation in a potassium channel that prevents inhibition by protein kinase C.

PubMed ID: 1553557

DOI: 10.1126/science.1553557

PubMed ID: 7605639

Title: Subunit composition of minK potassium channels.

PubMed ID: 7605639

DOI: 10.1016/0896-6273(95)90277-5

PubMed ID: 14679187

Title: MinK, MiRP1, and MiRP2 diversify Kv3.1 and Kv3.2 potassium channel gating.

PubMed ID: 14679187

DOI: 10.1074/jbc.m310501200

PubMed ID: 19219384

Title: Regulation of the Kv2.1 potassium channel by MinK and MiRP1.

PubMed ID: 19219384

DOI: 10.1007/s00232-009-9154-8

Sequence Information:

  • Length: 130
  • Mass: 14699
  • Checksum: 76717E7ED73C5E4D
  • Sequence:
    • MALSNSTTVL PFLASLWQET DEPGGNMSAD LARRSQLRDD SKLEALYILM VLGFFGFFTL 
GIMLSYIRSK KLEHSHDPFN VYIESDAWQE KGKALFQARV LESFRACYVI ENQAAVEQPA 
THLPELKPLS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.