Details for: Lhcgr

Gene ID: 25477

Symbol: Lhcgr

Ensembl ID: ENSRNOG00000016712

Description: luteinizing hormone/choriogonadotropin receptor

Associated with

Other Information

Genular Protein ID: 3917879518

Symbol: LSHR_RAT

Name: Lutropin-choriogonadotropic hormone receptor

UniProtKB Accession Codes:

P16235 P70646 Q63807 Q63808 Q63809 Q6LDI7

Database IDs:

AGR 1 AlphaFoldDB 1 BindingDB 1 CDD 1 CTD 1 ChEMBL 1 DrugCentral 1 EMBL 65 Ensembl 6 GO 39 Gene3D 2 GeneTree 1 GlyCosmos 1 GlyGen 1 InParanoid 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 3 PRINTS 3 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 1 RefSeq 1 SMR 1 STRING 1 SUPFAM 2 SwissPalm 1 UCSC 1 UniProtKB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 2502842

Title: Lutropin-choriogonadotropin receptor: an unusual member of the G protein-coupled receptor family.

PubMed ID: 2502842

DOI: 10.1126/science.2502842

PubMed ID: 1353463

Title: Expression of the LH/CG receptor gene in rat ovarian tissue is regulated by an extensive alternative splicing of the primary transcript.

PubMed ID: 1353463

DOI: 10.1016/0303-7207(92)90079-l

PubMed ID: 2019252

Title: Structure of the luteinizing hormone receptor gene and multiple exons of the coding sequence.

PubMed ID: 2019252

DOI: 10.1210/endo-128-5-2297

PubMed ID: 1976554

Title: Cloning of rat lutropin (LH) receptor analogs lacking the soybean lectin domain.

PubMed ID: 1976554

DOI: 10.1016/0303-7207(90)90034-6

PubMed ID: 2281186

Title: Structure of the lutropin/choriogonadotropin receptor.

PubMed ID: 2281186

DOI: 10.1016/b978-0-12-571146-3.50014-6

PubMed ID: 2040640

Title: Structural organization of the rat luteinizing hormone (LH) receptor gene.

PubMed ID: 2040640

DOI: 10.1016/s0021-9258(18)99170-2

PubMed ID: 2174034

Title: Intronic nature of the rat luteinizing hormone receptor gene defines a soluble receptor subspecies with hormone binding activity.

PubMed ID: 2174034

DOI: 10.1016/s0021-9258(17)45380-4

PubMed ID: 2601325

Title: Characterization and structure of ovarian and testicular LH/hCG receptors.

PubMed ID: 2601325

DOI: 10.1016/0022-4731(89)90482-2

PubMed ID: 2925659

Title: Purification, characterization, and amino-terminal sequence of rat ovarian receptor for luteinizing hormone/human choriogonadotropin.

PubMed ID: 2925659

DOI: 10.1016/s0021-9258(18)83790-5

PubMed ID: 1714448

Title: Asp383 in the second transmembrane domain of the lutropin receptor is important for high affinity hormone binding and cAMP production.

PubMed ID: 1714448

DOI: 10.1016/s0021-9258(18)98570-4

PubMed ID: 7776964

Title: The lutropin/choriogonadotropin receptor is palmitoylated at intracellular cysteine residues.

PubMed ID: 7776964

DOI: 10.1210/mend.9.2.7776964

Sequence Information:

  • Length: 700
  • Mass: 78036
  • Checksum: 31807E73BAC94F1F
  • Sequence:
    • MGRRVPALRQ LLVLAVLLLK PSQLQSRELS GSRCPEPCDC APDGALRCPG PRAGLARLSL 
TYLPVKVIPS QAFRGLNEVV KIEISQSDSL ERIEANAFDN LLNLSELLIQ NTKNLLYIEP 
GAFTNLPRLK YLSICNTGIR TLPDVTKISS SEFNFILEIC DNLHITTIPG NAFQGMNNES 
VTLKLYGNGF EEVQSHAFNG TTLISLELKE NIYLEKMHSG AFQGATGPSI LDISSTKLQA 
LPSHGLESIQ TLIALSSYSL KTLPSKEKFT SLLVATLTYP SHCCAFRNLP KKEQNFSFSI 
FENFSKQCES TVRKADNETL YSAIFEENEL SGWDYDYGFC SPKTLQCAPE PDAFNPCEDI 
MGYAFLRVLI WLINILAIFG NLTVLFVLLT SRYKLTVPRF LMCNLSFADF CMGLYLLLIA 
SVDSQTKGQY YNHAIDWQTG SGCGAAGFFT VFASELSVYT LTVITLERWH TITYAVQLDQ 
KLRLRHAIPI MLGGWLFSTL IATMPLVGIS NYMKVSICLP MDVESTLSQV YILSILILNV 
VAFVVICACY IRIYFAVQNP ELTAPNKDTK IAKKMAILIF TDFTCMAPIS FFAISAAFKV 
PLITVTNSKI LLVLFYPVNS CANPFLYAIF TKAFQRDFLL LLSRFGCCKR RAELYRRKEF 
SAYTSNCKNG FPGASKPSQA TLKLSTVHCQ QPIPPRALTH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.