Npm1 | ENSRNOG00000004616 | NCBI 25498

Details for: Npm1

Gene ID: 25498

Symbol: Npm1

Ensembl ID: ENSRNOG00000004616

Description: nucleophosmin 1

Associated with

Antiviral mechanism by ifn-stimulated genes
(R-RNO-1169410)
Cell cycle
(R-RNO-1640170)
Chromosome maintenance
(R-RNO-73886)
Cytokine signaling in immune system
(R-RNO-1280215)
Deposition of new cenpa-containing nucleosomes at the centromere
(R-RNO-606279)
Gene expression (transcription)
(R-RNO-74160)
Generic transcription pathway
(R-RNO-212436)
Immune system
(R-RNO-168256)
Interferon signaling
(R-RNO-913531)
Metabolism of proteins
(R-RNO-392499)
Pkr-mediated signaling
(R-RNO-9833482)
Post-translational protein modification
(R-RNO-597592)
Rna polymerase ii transcription
(R-RNO-73857)
Sumo e3 ligases sumoylate target proteins
(R-RNO-3108232)
Sumoylation
(R-RNO-2990846)
Sumoylation of transcription cofactors
(R-RNO-3899300)
Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation
(R-RNO-8869496)
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
(R-RNO-6804115)
Tp53 regulates transcription of cell cycle genes
(R-RNO-6791312)
Transcriptional regulation by the ap-2 (tfap2) family of transcription factors
(R-RNO-8864260)
Transcriptional regulation by tp53
(R-RNO-3700989)
Atp binding
(GO:0005524)
Cardiac muscle hypertrophy
(GO:0003300)
Cellular response to hypoxia
(GO:0071456)
Cellular response to testosterone stimulus
(GO:0071394)
Cellular response to uv
(GO:0034644)
Cellular senescence
(GO:0090398)
Cell volume homeostasis
(GO:0006884)
Centrosome cycle
(GO:0007098)
Chromatin binding
(GO:0003682)
Chromatin remodeling
(GO:0006338)
Cleavage in its2 between 5.8s rrna and lsu-rrna of tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna)
(GO:0000448)
Core promoter sequence-specific dna binding
(GO:0001046)
Dna-binding transcription factor binding
(GO:0140297)
Dna binding
(GO:0003677)
Dna repair
(GO:0006281)
Enzyme binding
(GO:0019899)
Granular component
(GO:0001652)
Histone binding
(GO:0042393)
Identical protein binding
(GO:0042802)
Liver regeneration
(GO:0097421)
Molecular condensate scaffold activity
(GO:0140693)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of cardiac muscle cell apoptotic process
(GO:0010667)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of centrosome duplication
(GO:0010826)
Negative regulation of epithelial cell proliferation
(GO:0050680)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of mrna splicing, via spliceosome
(GO:0048025)
Negative regulation of neuron apoptotic process
(GO:0043524)
Nf-kappab binding
(GO:0051059)
Nucleocytoplasmic transport
(GO:0006913)
Nucleosome assembly
(GO:0006334)
P53 binding
(GO:0002039)
Phosphatidylinositol-3,4,5-trisphosphate binding
(GO:0005547)
Positive regulation of cell cycle g2/m phase transition
(GO:1902751)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cellular biosynthetic process
(GO:0031328)
Positive regulation of centrosome duplication
(GO:0010825)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of dna metabolic process
(GO:0051054)
Positive regulation of dna replication
(GO:0045740)
Positive regulation of protein localization to nucleolus
(GO:1904751)
Positive regulation of protein ubiquitination
(GO:0031398)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of translation
(GO:0045727)
Post-transcriptional regulation of gene expression
(GO:0010608)
Protein binding
(GO:0005515)
Protein destabilization
(GO:0031648)
Protein homodimerization activity
(GO:0042803)
Protein kinase b binding
(GO:0043422)
Protein kinase binding
(GO:0019901)
Protein kinase inhibitor activity
(GO:0004860)
Protein localization
(GO:0008104)
Protein stabilization
(GO:0050821)
Regulation of cell cycle
(GO:0051726)
Regulation of cell growth
(GO:0001558)
Regulation of centriole replication
(GO:0046599)
Regulation of centrosome duplication
(GO:0010824)
Regulation of dna damage response, signal transduction by p53 class mediator
(GO:0043516)
Regulation of eif2 alpha phosphorylation by dsrna
(GO:0060735)
Regulation of mrna stability involved in cellular response to uv
(GO:1902629)
Regulation of neuron apoptotic process
(GO:0043523)
Regulation of protein stability
(GO:0031647)
Ribosomal large subunit binding
(GO:0043023)
Ribosomal large subunit biogenesis
(GO:0042273)
Ribosomal large subunit export from nucleus
(GO:0000055)
Ribosomal small subunit binding
(GO:0043024)
Ribosomal small subunit biogenesis
(GO:0042274)
Ribosomal small subunit export from nucleus
(GO:0000056)
Ribosomal subunit export from nucleus
(GO:0000054)
Rna binding
(GO:0003723)
Rrna binding
(GO:0019843)
Rrna transcription
(GO:0009303)
Tat protein binding
(GO:0030957)
Transcription coactivator activity
(GO:0003713)
Unfolded protein binding
(GO:0051082)

Other Information

Proteins

Nucleophosmin

Genular Protein ID: 4013448720

Symbol: NPM_RAT

Name: Nucleophosmin

UniProtKB Accession Codes:

P13084 Q63698 Q64269

Database IDs:

Citations:

PubMed ID: 3417636

Title: cDNA and deduced primary structure of rat protein B23, a nucleolar protein containing highly conserved sequences.

PubMed ID: 3417636

DOI: 10.1016/s0021-9258(18)37633-6

PubMed ID: 2745414

Title: A single gene codes for two forms of rat nucleolar protein B23 mRNA.

PubMed ID: 2745414

DOI: 10.1016/s0021-9258(18)80126-0

PubMed ID: 2211699

Title: Structure of the gene for rat nucleolar protein B23.

PubMed ID: 2211699

DOI: 10.1016/s0021-9258(17)44742-9

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 20075868

Title: Nucleolar retention of a translational C/EBPalpha isoform stimulates rDNA transcription and cell size.

PubMed ID: 20075868

DOI: 10.1038/emboj.2009.404

Sequence Information:

Length: 292
Mass: 32560
Checksum: 1372A474F9ED2457
Sequence:

MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG AGAKDELHIV 
EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL RLKCGSGPVH ISGQHLVAVE 
EDAESEDEDE EDVKLLGMSG KRSAPGGGNK VPQKKVKLDE DDDEDDEDDE DDEDDDDDDF 
DEEETEEKVP VKKSVRDTPA KNAQKSNQNG KDLKPSTPRS KGQESFKKQE KTPKTPKGPS 
SVEDIKAKMQ ASIEKGGSLP KVEAKFINYV KNCFRMTDQE AIQDLWQWRK SL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Npm1

Associated with

Other Information

cDNA and deduced primary structure of rat protein B23, a nucleolar protein containing highly conserved sequences. PubMed ID: 3417636

A single gene codes for two forms of rat nucleolar protein B23 mRNA. PubMed ID: 2745414

Structure of the gene for rat nucleolar protein B23. PubMed ID: 2211699