Pax6 | ENSRNOG00000004410 | NCBI 25509

Details for: Pax6

Gene ID: 25509

Symbol: Pax6

Ensembl ID: ENSRNOG00000004410

Description: paired box 6

Associated with

Anterior/posterior pattern specification
(GO:0009952)
Axon guidance
(GO:0007411)
Axonogenesis
(GO:0007409)
Blood vessel development
(GO:0001568)
Brain development
(GO:0007420)
Camera-type eye development
(GO:0043010)
Cell differentiation
(GO:0030154)
Cell fate determination
(GO:0001709)
Cell population proliferation
(GO:0008283)
Cellular response to fibroblast growth factor stimulus
(GO:0044344)
Cellular response to insulin stimulus
(GO:0032869)
Cerebellum development
(GO:0021549)
Cerebral cortex development
(GO:0021987)
Cerebral cortex regionalization
(GO:0021796)
Chromatin binding
(GO:0003682)
Chromatin dna binding
(GO:0031490)
Chromatin remodeling
(GO:0006338)
Co-smad binding
(GO:0070410)
Commitment of neuronal cell to specific neuron type in forebrain
(GO:0021902)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Dna methylation
(GO:0006306)
Dorsal/ventral axis specification
(GO:0009950)
Dorsal/ventral pattern formation
(GO:0009953)
Double-stranded dna binding
(GO:0003690)
Epithelial cell development
(GO:0002064)
Establishment of mitotic spindle orientation
(GO:0000132)
Eye photoreceptor cell development
(GO:0042462)
Forebrain-midbrain boundary formation
(GO:0021905)
Forebrain development
(GO:0030900)
Forebrain dorsal/ventral pattern formation
(GO:0021798)
Gene expression
(GO:0010467)
Glandular epithelial cell differentiation
(GO:0002067)
Glucose homeostasis
(GO:0042593)
Habenula development
(GO:0021986)
Hindbrain development
(GO:0030902)
Histone acetyltransferase binding
(GO:0035035)
Hmg box domain binding
(GO:0071837)
Interkinetic nuclear migration
(GO:0022027)
Keratinocyte differentiation
(GO:0030216)
Lacrimal gland development
(GO:0032808)
Lens development in camera-type eye
(GO:0002088)
Minor groove of adenine-thymine-rich dna binding
(GO:0003680)
Negative regulation of neuroblast proliferation
(GO:0007406)
Negative regulation of protein phosphorylation
(GO:0001933)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nervous system development
(GO:0007399)
Neural crest cell migration
(GO:0001755)
Neuroblast proliferation
(GO:0007405)
Neuron differentiation
(GO:0030182)
Neuron migration
(GO:0001764)
Olfactory bulb development
(GO:0021772)
Oligodendrocyte cell fate specification
(GO:0021778)
Pallium development
(GO:0021543)
Pancreatic a cell development
(GO:0003322)
Pancreatic a cell differentiation
(GO:0003310)
Pituitary gland development
(GO:0021983)
Positive regulation of cell fate specification
(GO:0042660)
Positive regulation of epithelial cell differentiation
(GO:0030858)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of neuroblast proliferation
(GO:0002052)
Protein kinase binding
(GO:0019901)
Protein localization to organelle
(GO:0033365)
R-smad binding
(GO:0070412)
Regionalization
(GO:0003002)
Regulation of asymmetric cell division
(GO:0009786)
Regulation of cell migration
(GO:0030334)
Regulation of gene expression
(GO:0010468)
Regulation of neuron projection development
(GO:0010975)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to wounding
(GO:0009611)
Rhombomere morphogenesis
(GO:0021593)
Rna binding
(GO:0003723)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii core promoter sequence-specific dna binding
(GO:0000979)
Salivary gland morphogenesis
(GO:0007435)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Signal transduction involved in regulation of gene expression
(GO:0023019)
Smoothened signaling pathway
(GO:0007224)
Spinal cord development
(GO:0021510)
Telencephalon regionalization
(GO:0021978)
Transcription by rna polymerase ii
(GO:0006366)
Transcription cis-regulatory region binding
(GO:0000976)
Transcription coregulator binding
(GO:0001221)
Type b pancreatic cell differentiation
(GO:0003309)
Ubiquitin protein ligase binding
(GO:0031625)
Ventral spinal cord development
(GO:0021517)

Other Information

Proteins

Paired box protein Pax-6

Genular Protein ID: 938951665

Symbol: PAX6_RAT

Name: Paired box protein Pax-6

UniProtKB Accession Codes:

P63016 A1A5N7 P32117 P70601 Q62222 Q64037 Q6QHS5 Q701Q8

Database IDs:

Citations:

PubMed ID: 24952136

Title: Cloning, expression, and functional characterization of the rat Pax6 5a orthologous splicing variant.

PubMed ID: 24952136

DOI: 10.1016/j.gene.2014.06.032

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7981749

Title: A mutation in the Pax-6 gene in rat small eye is associated with impaired migration of midbrain crest cells.

PubMed ID: 7981749

DOI: 10.1038/ng0493-299

PubMed ID: 11880342

Title: Pax6 regulates specification of ventral neurone subtypes in the hindbrain by establishing progenitor domains.

PubMed ID: 11880342

DOI: 10.1242/dev.129.6.1327

PubMed ID: 24114637

Title: Transcription factor Pax6 is expressed by astroglia after transient brain ischemia in the rat model.

PubMed ID: 24114637

DOI: 10.5114/fn.2013.37704

Sequence Information:

Length: 422
Mass: 46754
Checksum: B0B2E5C176A518FE
Sequence:

MQNSHSGVNQ LGGVFVNGRP LPDSTRQKIV ELAHSGARPC DISRILQVSN GCVSKILGRY 
YETGSIRPRA IGGSKPRVAT PEVVSKIAQY KRECPSIFAW EIRDRLLSEG VCTNDNIPSV 
SSINRVLRNL ASEKQQMGAD GMYDKLRMLN GQTGSWGTRP GWYPGTSVPG QPTQDGCQQQ 
EGQGENTNSI SSNGEDSDEA QMRLQLKRKL QRNRTSFTQE QIEALEKEFE RTHYPDVFAR 
ERLAAKIDLP EARIQVWFSN RRAKWRREEK LRNQRRQASN TPSHIPISSS FSTSVYQPIP 
QPTTPVSSFT SGSMLGRTDT ALTNTYSALP PMPSFTMANN LPMQPPVPSQ TSSYSCMLPT 
SPSVNGRSYD TYTPPHMQTH MNSQPMGTSG TTSTGLISPG VSVPVQVPGS EPDMSQYWPR 
LQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pax6

Associated with

Other Information

Cloning, expression, and functional characterization of the rat Pax6 5a orthologous splicing variant. PubMed ID: 24952136

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A mutation in the Pax-6 gene in rat small eye is associated with impaired migration of midbrain crest cells. PubMed ID: 7981749