Plk1 | ENSRNOG00000018815 | NCBI 25515

Details for: Plk1

Gene ID: 25515

Symbol: Plk1

Ensembl ID: ENSRNOG00000018815

Description: polo-like kinase 1

Associated with

Activation of apc/c and apc/c:cdc20 mediated degradation of mitotic proteins
(R-RNO-176814)
Activation of nima kinases nek9, nek6, nek7
(R-RNO-2980767)
Amplification of signal from the kinetochores
(R-RNO-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-RNO-141444)
Anchoring of the basal body to the plasma membrane
(R-RNO-5620912)
Apc/c-mediated degradation of cell cycle proteins
(R-RNO-174143)
Apc/c:cdh1 mediated degradation of cdc20 and other apc/c:cdh1 targeted proteins in late mitosis/early g1
(R-RNO-174178)
Aurka activation by tpx2
(R-RNO-8854518)
Cell cycle
(R-RNO-1640170)
Cell cycle, mitotic
(R-RNO-69278)
Cell cycle checkpoints
(R-RNO-69620)
Centrosome maturation
(R-RNO-380287)
Cilium assembly
(R-RNO-5617833)
Condensation of prophase chromosomes
(R-RNO-2299718)
Cyclin a/b1/b2 associated events during g2/m transition
(R-RNO-69273)
Eml4 and nudc in mitotic spindle formation
(R-RNO-9648025)
G2/m transition
(R-RNO-69275)
Golgi cisternae pericentriolar stack reorganization
(R-RNO-162658)
Loss of nlp from mitotic centrosomes
(R-RNO-380259)
Loss of proteins required for interphase microtubule organization from the centrosome
(R-RNO-380284)
Mitotic anaphase
(R-RNO-68882)
Mitotic g2-g2/m phases
(R-RNO-453274)
Mitotic metaphase/anaphase transition
(R-RNO-68881)
Mitotic metaphase and anaphase
(R-RNO-2555396)
Mitotic prometaphase
(R-RNO-68877)
Mitotic prophase
(R-RNO-68875)
Mitotic spindle checkpoint
(R-RNO-69618)
Mitotic telophase/cytokinesis
(R-RNO-68884)
M phase
(R-RNO-68886)
Nuclear envelope breakdown
(R-RNO-2980766)
Organelle biogenesis and maintenance
(R-RNO-1852241)
Phosphorylation of emi1
(R-RNO-176417)
Phosphorylation of the apc/c
(R-RNO-176412)
Polo-like kinase mediated events
(R-RNO-156711)
Recruitment of mitotic centrosome proteins and complexes
(R-RNO-380270)
Recruitment of numa to mitotic centrosomes
(R-RNO-380320)
Regulation of apc/c activators between g1/s and early anaphase
(R-RNO-176408)
Regulation of plk1 activity at g2/m transition
(R-RNO-2565942)
Resolution of sister chromatid cohesion
(R-RNO-2500257)
Rho gtpase effectors
(R-RNO-195258)
Rho gtpases activate formins
(R-RNO-5663220)
Separation of sister chromatids
(R-RNO-2467813)
Signaling by rho gtpases
(R-RNO-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-RNO-9716542)
Signal transduction
(R-RNO-162582)
The role of gtse1 in g2/m progression after g2 checkpoint
(R-RNO-8852276)
Anaphase-promoting complex binding
(GO:0010997)
Atp binding
(GO:0005524)
Centrosome cycle
(GO:0007098)
Chromatin
(GO:0000785)
Chromosome, centromeric region
(GO:0000775)
Condensed chromosome, centromeric region
(GO:0000779)
Cytoplasm
(GO:0005737)
Double-strand break repair
(GO:0006302)
Double-strand break repair via alternative nonhomologous end joining
(GO:0097681)
Establishment of mitotic spindle orientation
(GO:0000132)
Establishment of protein localization
(GO:0045184)
Female meiosis chromosome segregation
(GO:0016321)
G2/m transition of mitotic cell cycle
(GO:0000086)
Homologous chromosome segregation
(GO:0045143)
Identical protein binding
(GO:0042802)
Kinetochore
(GO:0000776)
Magnesium ion binding
(GO:0000287)
Microtubule binding
(GO:0008017)
Microtubule bundle formation
(GO:0001578)
Mitotic cell cycle
(GO:0000278)
Mitotic cytokinesis
(GO:0000281)
Mitotic g2 dna damage checkpoint signaling
(GO:0007095)
Mitotic sister chromatid segregation
(GO:0000070)
Mitotic spindle assembly checkpoint signaling
(GO:0007094)
Mitotic spindle organization
(GO:0007052)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nuclear membrane disassembly
(GO:0051081)
Nucleus
(GO:0005634)
Outer kinetochore
(GO:0000940)
Phosphorylation
(GO:0016310)
Polar body extrusion after meiotic divisions
(GO:0040038)
Positive regulation of peptidyl-threonine phosphorylation
(GO:0010800)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032436)
Positive regulation of proteolysis
(GO:0045862)
Protein destabilization
(GO:0031648)
Protein kinase activity
(GO:0004672)
Protein kinase binding
(GO:0019901)
Protein localization to chromatin
(GO:0071168)
Protein localization to nuclear envelope
(GO:0090435)
Protein localization to organelle
(GO:0033365)
Protein serine/threonine kinase activity
(GO:0004674)
Protein serine kinase activity
(GO:0106310)
Protein ubiquitination
(GO:0016567)
Regulation of cytokinesis
(GO:0032465)
Regulation of mitotic cell cycle
(GO:0007346)
Regulation of mitotic metaphase/anaphase transition
(GO:0030071)
Regulation of mitotic spindle assembly
(GO:1901673)
Regulation of protein localization to cell cortex
(GO:1904776)
Spindle pole
(GO:0000922)
Synaptonemal complex
(GO:0000795)
Synaptonemal complex disassembly
(GO:0070194)

Other Information

Proteins

Serine/threonine-protein kinase PLK1

Genular Protein ID: 1523930509

Symbol: PLK1_RAT

Name: Serine/threonine-protein kinase PLK1

UniProtKB Accession Codes:

Q62673 F1LNH6 Q5XHX4

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 603
Mass: 68291
Checksum: D756DD742CB14F6E
Sequence:

MNAAAKAGKL ARAPADLGKG GVPGDAAPGA PGAAPLAKEI PEVLMDPRSR RQYVRGRFLG 
KGGFAKCFEI SDSDTKEVFP GKIVPKSLLL KPHQKEKMSM EISIHRSLAH QHVVGFHGFF 
EDSDFVFVVL ELCRRRSLLE LHKRRKALTE PEARYYLRQI VLGCQYLHRN QVIHRDLKLG 
NLFLNEDLEV KIGDFGLATK VEYEGERKKT LCGTPNYIAP EVLSKKGHSF EVDVWSIGCI 
MYTLLVGKPP FETSCLKETY LRIKKNEYSI PKHINPVAAS LIQKMLQTDP TARPTIHELL 
NDEFFTSGYI PARLPITCLT IPPRFSIAPS SLDPSNRKPL TVLNKGVENP LPDRPREKEE 
PVVRETNEAI ECHLSDLLQQ LTSVNASKPS ERGLVRQEEA EDPACIPIFW VSKWVDYSDK 
YGLGYQLCDN SVGVLFNDST RLILYNDGDS LQYIERDGTE SYLTVSSHPN SLMKKITLLN 
YFRNYMSEHL LKAGANITPR EGDELARLPY LRTWFRTRSA IILHLSNGTV QINFFQDHTK 
LILCPLMAAV TYINEKRDFR TYRLSLLEEY GCCKELASRL RYARTMVDKL LSSRSACNRL 
KAS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Plk1

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Database document:

PubMed ID: 15489334