Prkcz | ENSRNOG00000015480 | NCBI 25522

Details for: Prkcz

Gene ID: 25522

Symbol: Prkcz

Ensembl ID: ENSRNOG00000015480

Description: protein kinase C, zeta

Associated with

Esr-mediated signaling
(R-RNO-8939211)
Estrogen-stimulated signaling through prkcz
(R-RNO-9634635)
Extra-nuclear estrogen signaling
(R-RNO-9009391)
Rho gtpase effectors
(R-RNO-195258)
Rho gtpases activate nadph oxidases
(R-RNO-5668599)
Signaling by nuclear receptors
(R-RNO-9006931)
Signaling by receptor tyrosine kinases
(R-RNO-9006934)
Signaling by rho gtpases
(R-RNO-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-RNO-9716542)
Signaling by tgf-beta receptor complex
(R-RNO-170834)
Signaling by tgfb family members
(R-RNO-9006936)
Signaling by vegf
(R-RNO-194138)
Signal transduction
(R-RNO-162582)
Tgf-beta receptor signaling in emt (epithelial to mesenchymal transition)
(R-RNO-2173791)
Vegfa-vegfr2 pathway
(R-RNO-4420097)
Vegfr2 mediated cell proliferation
(R-RNO-5218921)
14-3-3 protein binding
(GO:0071889)
Apical cortex
(GO:0045179)
Apical plasma membrane
(GO:0016324)
Atp binding
(GO:0005524)
Axon hillock
(GO:0043203)
Bicellular tight junction
(GO:0005923)
Cell-cell junction
(GO:0005911)
Cell cortex
(GO:0005938)
Cell leading edge
(GO:0031252)
Cell migration
(GO:0016477)
Cell surface receptor signaling pathway
(GO:0007166)
Cellular response to insulin stimulus
(GO:0032869)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Diacylglycerol-dependent serine/threonine kinase activity
(GO:0004697)
Endosome
(GO:0005768)
Establishment of cell polarity
(GO:0030010)
Glutamatergic synapse
(GO:0098978)
Inflammatory response
(GO:0006954)
Intracellular signal transduction
(GO:0035556)
Long-term memory
(GO:0007616)
Long-term synaptic potentiation
(GO:0060291)
Membrane depolarization
(GO:0051899)
Membrane hyperpolarization
(GO:0060081)
Metal ion binding
(GO:0046872)
Microtubule cytoskeleton organization
(GO:0000226)
Microtubule organizing center
(GO:0005815)
Myelin sheath abaxonal region
(GO:0035748)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of insulin receptor signaling pathway
(GO:0046627)
Negative regulation of peptidyl-tyrosine phosphorylation
(GO:0050732)
Negative regulation of protein-containing complex assembly
(GO:0031333)
Neuron projection extension
(GO:1990138)
Nuclear envelope
(GO:0005635)
Nuclear matrix
(GO:0016363)
Nucleus
(GO:0005634)
Peptidyl-serine phosphorylation
(GO:0018105)
Perinuclear region of cytoplasm
(GO:0048471)
Phospholipase binding
(GO:0043274)
Phosphorylation
(GO:0016310)
Plasma membrane
(GO:0005886)
Positive regulation of cell-matrix adhesion
(GO:0001954)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of excitatory postsynaptic potential
(GO:2000463)
Positive regulation of insulin receptor signaling pathway
(GO:0046628)
Positive regulation of interleukin-4 production
(GO:0032753)
Positive regulation of interleukin-5 production
(GO:0032754)
Positive regulation of interleukin-10 production
(GO:0032733)
Positive regulation of interleukin-13 production
(GO:0032736)
Positive regulation of protein transport
(GO:0051222)
Positive regulation of synaptic transmission
(GO:0050806)
Positive regulation of t-helper 2 cell cytokine production
(GO:2000553)
Positive regulation of t-helper 2 cell differentiation
(GO:0045630)
Postsynaptic density
(GO:0014069)
Potassium channel regulator activity
(GO:0015459)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein kinase binding
(GO:0019901)
Protein kinase c signaling
(GO:0070528)
Protein localization to plasma membrane
(GO:0072659)
Protein serine/threonine kinase activity
(GO:0004674)
Protein serine kinase activity
(GO:0106310)
Regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
(GO:0098696)
Schaffer collateral - ca1 synapse
(GO:0098685)
Stress fiber
(GO:0001725)
Vesicle
(GO:0031982)
Vesicle transport along microtubule
(GO:0047496)

Other Information

Proteins

Protein kinase C zeta type
A6IUP4_RAT

Genular Protein ID: 2814720726

Symbol: KPCZ_RAT

Name: Protein kinase C zeta type

UniProtKB Accession Codes:

P09217

Database IDs:

Citations:

PubMed ID: 2470089

Title: Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties.

PubMed ID: 2470089

DOI: 10.1073/pnas.86.9.3099

PubMed ID: 2834397

Title: The structure, expression, and properties of additional members of the protein kinase C family.

PubMed ID: 2834397

DOI: 10.1016/s0021-9258(18)68732-0

PubMed ID: 3691811

Title: Identification of three additional members of rat protein kinase C family: delta-, epsilon- and zeta-subspecies.

PubMed ID: 3691811

DOI: 10.1016/0014-5793(87)80564-1

PubMed ID: 8378304

Title: Persistent activation of the zeta isoform of protein kinase C in the maintenance of long-term potentiation.

PubMed ID: 8378304

DOI: 10.1073/pnas.90.18.8342

PubMed ID: 8557035

Title: Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta.

PubMed ID: 8557035

DOI: 10.1002/j.1460-2075.1995.tb00306.x

PubMed ID: 9374484

Title: Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport.

PubMed ID: 9374484

DOI: 10.1074/jbc.272.48.30075

PubMed ID: 9177193

Title: Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein.

PubMed ID: 9177193

DOI: 10.1073/pnas.94.12.6191

PubMed ID: 10022904

Title: Activation of IkappaB kinase beta by protein kinase C isoforms.

PubMed ID: 10022904

DOI: 10.1128/mcb.19.3.2180

PubMed ID: 10747026

Title: The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway.

PubMed ID: 10747026

DOI: 10.1093/emboj/19.7.1576

PubMed ID: 11525734

Title: Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta.

PubMed ID: 11525734

DOI: 10.1016/s0092-8674(01)00471-8

PubMed ID: 11158308

Title: MEK5, a new target of the atypical protein kinase C isoforms in mitogenic signaling.

PubMed ID: 11158308

DOI: 10.1128/mcb.21.4.1218-1227.2001

PubMed ID: 11914719

Title: Protein kinase Mzeta is necessary and sufficient for LTP maintenance.

PubMed ID: 11914719

DOI: 10.1038/nn829

PubMed ID: 12431995

Title: ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2.

PubMed ID: 12431995

DOI: 10.1074/jbc.m205162200

PubMed ID: 12813044

Title: Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.

PubMed ID: 12813044

DOI: 10.1074/jbc.m303221200

PubMed ID: 12857744

Title: Protein kinase M zeta synthesis from a brain mRNA encoding an independent protein kinase C zeta catalytic domain. Implications for the molecular mechanism of memory.

PubMed ID: 12857744

DOI: 10.1074/jbc.m307065200

PubMed ID: 14580237

Title: Molecular mechanisms regulating protein kinase Czeta turnover and cellular transformation.

PubMed ID: 14580237

DOI: 10.1042/bj20031194

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 27498875

Title: Distinct Roles of PKCiota/lambda and PKMzeta in the Initiation and Maintenance of Hippocampal Long-Term Potentiation and Memory.

PubMed ID: 27498875

DOI: 10.1016/j.celrep.2016.07.030

Sequence Information:

Length: 592
Mass: 67733
Checksum: 5A3021171C2FD7C7
Sequence:

MPSRTDPKMD RSGGRVRLKA HYGGDILITS VDPTTTFQDL CEEVRDMCGL HQQHPLTLKW 
VDSEGDPCTV SSQMELEEAF RLACQGRDEV LIIHVFPSIP EQPGMPCPGE DKSIYRRGAR 
RWRKLYRANG HLFQAKRFNR RAYCGQCSER IWGLARQGYR CINCKLLVHK RCHVLVPLTC 
RRHMDSVMPS QEPPVDDKND GVDLPSEETD GIAYISSSRK HDNIKDDSED LKPVIDGVDG 
IKISQGLGLQ DFDLIRVIGR GSYAKVLLVR LKKNDQIYAM KVVKKELVHD DEDIDWVQTE 
KHVFEQASSN PFLVGLHSCF QTTSRLFLVI EYVNGGDLMF HMQRQRKLPE EHARFYAAEI 
CIALNFLHER GIIYRDLKLD NVLLDADGHI KLTDYGMCKE GLGPGDTTST FCGTPNYIAP 
EILRGEEYGF SVDWWALGVL MFEMMAGRSP FDIITDNPDM NTEDYLFQVI LEKPIRIPRF 
LSVKASHVLK GFLNKDPKER LGCRPQTGFS DIKSHAFFRS IDWDLLEKKQ TLPPFQPQIT 
DDYGLDNFDT QFTSEPVQLT PDDEDVIKRI DQSEFEGFEY INPLLLSAEE SV

Genular Protein ID: 2775137496

Symbol: A6IUP4_RAT

Name: N/A

UniProtKB Accession Codes:

A6IUP4

Database IDs:

Citations:

PubMed ID: 15632090

Title: Gene and alternative splicing annotation with AIR.

PubMed ID: 15632090

DOI: 10.1101/gr.2889405

Sequence Information:

Length: 409
Mass: 46601
Checksum: F233CE0BBD7D324E
Sequence:

MDSVMPSQEP PVDDKNDGVD LPSEETDGIA YISSSRKHDN IKDDSEDLKP VIDGVDGIKI 
SQGLGLQDFD LIRVIGRGSY AKVLLVRLKK NDQIYAMKVV KKELVHDDED IDWVQTEKHV 
FEQASSNPFL VGLHSCFQTT SRLFLVIEYV NGGDLMFHMQ RQRKLPEEHA RFYAAEICIA 
LNFLHERGII YRDLKLDNVL LDADGHIKLT DYGMCKEGLG PGDTTSTFCG TPNYIAPEIL 
RGEEYGFSVD WWALGVLMFE MMAGRSPFDI ITDNPDMNTE DYLFQVILEK PIRIPRFLSV 
KASHVLKGFL NKDPKERLGC RPQTGFSDIK SHAFFRSIDW DLLEKKQTLP PFQPQITDDY 
GLDNFDTQFT SEPVQLTPDD EDVIKRIDQS EFEGFEYINP LLLSAEESV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Prkcz

Associated with

Other Information

Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties. PubMed ID: 2470089

The structure, expression, and properties of additional members of the protein kinase C family. PubMed ID: 2834397

Identification of three additional members of rat protein kinase C family: delta-, epsilon- and zeta-subspecies. PubMed ID: 3691811

Persistent activation of the zeta isoform of protein kinase C in the maintenance of long-term potentiation. PubMed ID: 8378304

Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta. PubMed ID: 8557035

Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport. PubMed ID: 9374484

Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein. PubMed ID: 9177193

Activation of IkappaB kinase beta by protein kinase C isoforms. PubMed ID: 10022904

The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway. PubMed ID: 10747026

Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta. PubMed ID: 11525734

MEK5, a new target of the atypical protein kinase C isoforms in mitogenic signaling. PubMed ID: 11158308

Protein kinase Mzeta is necessary and sufficient for LTP maintenance. PubMed ID: 11914719

ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2. PubMed ID: 12431995

Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins. PubMed ID: 12813044

Protein kinase M zeta synthesis from a brain mRNA encoding an independent protein kinase C zeta catalytic domain. Implications for the molecular mechanism of memory. PubMed ID: 12857744

Molecular mechanisms regulating protein kinase Czeta turnover and cellular transformation. PubMed ID: 14580237

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903

Distinct Roles of PKCiota/lambda and PKMzeta in the Initiation and Maintenance of Hippocampal Long-Term Potentiation and Memory. PubMed ID: 27498875

Gene and alternative splicing annotation with AIR. PubMed ID: 15632090