Ptgis | ENSRNOG00000008245 | NCBI 25527

Details for: Ptgis

Gene ID: 25527

Symbol: Ptgis

Ensembl ID: ENSRNOG00000008245

Description: prostaglandin I2 synthase

Associated with

Arachidonic acid metabolism
(R-RNO-2142753)
Bile acid and bile salt metabolism
(R-RNO-194068)
Biological oxidations
(R-RNO-211859)
Cytochrome p450 - arranged by substrate type
(R-RNO-211897)
Eicosanoids
(R-RNO-211979)
Endogenous sterols
(R-RNO-211976)
Fatty acid metabolism
(R-RNO-8978868)
Metabolism
(R-RNO-1430728)
Metabolism of lipids
(R-RNO-556833)
Metabolism of steroids
(R-RNO-8957322)
Metabolism of vitamins and cofactors
(R-RNO-196854)
Metabolism of water-soluble vitamins and cofactors
(R-RNO-196849)
Nicotinamide salvaging
(R-RNO-197264)
Nicotinate metabolism
(R-RNO-196807)
Phase i - functionalization of compounds
(R-RNO-211945)
Sterols are 12-hydroxylated by cyp8b1
(R-RNO-211994)
Synthesis of bile acids and bile salts
(R-RNO-192105)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
(R-RNO-193368)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol
(R-RNO-193775)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol
(R-RNO-193807)
Synthesis of prostaglandins (pg) and thromboxanes (tx)
(R-RNO-2162123)
Apoptotic signaling pathway
(GO:0097190)
Caveola
(GO:0005901)
Cellular response to hypoxia
(GO:0071456)
Cellular response to interleukin-1
(GO:0071347)
Cellular response to interleukin-6
(GO:0071354)
Cytoplasm
(GO:0005737)
Decidualization
(GO:0046697)
Embryo implantation
(GO:0007566)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Fatty acid biosynthetic process
(GO:0006633)
Heme binding
(GO:0020037)
Hydroperoxy icosatetraenoate dehydratase activity
(GO:0106256)
Icosanoid metabolic process
(GO:0006690)
Iron ion binding
(GO:0005506)
Lyase activity
(GO:0016829)
Monooxygenase activity
(GO:0004497)
Negative regulation of inflammatory response
(GO:0050728)
Negative regulation of nitric oxide biosynthetic process
(GO:0045019)
Nucleus
(GO:0005634)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
(GO:0016705)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of execution phase of apoptosis
(GO:1900119)
Positive regulation of peroxisome proliferator activated receptor signaling pathway
(GO:0035360)
Prostaglandin-i synthase activity
(GO:0008116)
Prostaglandin biosynthetic process
(GO:0001516)
Response to alkaloid
(GO:0043279)
Response to hypoxia
(GO:0001666)
Response to organic cyclic compound
(GO:0014070)
Vasodilation
(GO:0042311)

Other Information

Proteins

Prostacyclin synthase

Genular Protein ID: 2916753092

Symbol: PTGIS_RAT

Name: Prostacyclin synthase

UniProtKB Accession Codes:

Q62969

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 501
Mass: 57128
Checksum: D2D85ADF3C464863
Sequence:

MSWAALLGLL AVLLLLLLLL SRRRARRPGE PPLDLGSIPW LGHALEFGKD AASFLTRMKE 
KHGDIFTVLV GGRYVTVLLD PHSYDTVVWD LRTRLDFHPY AIFLMERIFD LQLPNFNPSE 
EKARMKPTLM HKDLQALTEA MYTNLRTVLL GDSTEGGSGW QEKGLLEFSY SSLLSAGYLT 
LYGVEASPRT HESQALDRDH SADVFRTFRQ LDLMLPKLAR GSLSVGDKDH ACSVKSRLWK 
LLSPAGLASR ADRSSWLESY LRHLEEMGVS EDMQARALVL QLWATQGNMG PTAFWLLLFL 
LKNPEALDAV HAELKRIVWQ AEKPVLQMTA LPQKILDSMP VLDSVLNETL RLTAAPFITR 
EVMADLALPM ADRREFSLRR GDRLLLFPFL SPQKDPEIYT EPEVFKYNRF LNPDGSEKKD 
FYKDGKRLKN YNMPWGAGHN QCLGKSYAIN SIKQFVVLLL THFDLELVSE DTEVPEFDLS 
RYGFGLMQPE EDVPIRYRTR L

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ptgis

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Database document:

PubMed ID: 15489334