Scp2 | ENSRNOG00000011413 | NCBI 25541

Details for: Scp2

Gene ID: 25541

Symbol: Scp2

Ensembl ID: ENSRNOG00000011413

Description: sterol carrier protein 2

Associated with

Alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
(R-RNO-2046104)
Alpha-linolenic acid (ala) metabolism
(R-RNO-2046106)
Beta-oxidation of pristanoyl-coa
(R-RNO-389887)
Bile acid and bile salt metabolism
(R-RNO-194068)
Fatty acid metabolism
(R-RNO-8978868)
Metabolism
(R-RNO-1430728)
Metabolism of lipids
(R-RNO-556833)
Metabolism of steroids
(R-RNO-8957322)
Peroxisomal lipid metabolism
(R-RNO-390918)
Peroxisomal protein import
(R-RNO-9033241)
Protein localization
(R-RNO-9609507)
Synthesis of bile acids and bile salts
(R-RNO-192105)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
(R-RNO-193368)
Acetyl-coa c-acyltransferase activity
(GO:0003988)
Acetyl-coa c-myristoyltransferase activity
(GO:0050633)
Acyltransferase activity, transferring groups other than amino-acyl groups
(GO:0016747)
Bile acid metabolic process
(GO:0008206)
Cellular response to cholesterol
(GO:0071397)
Cholesterol binding
(GO:0015485)
Cholesterol transfer activity
(GO:0120020)
Cytoplasm
(GO:0005737)
Endoplasmic reticulum
(GO:0005783)
Fatty-acyl-coa binding
(GO:0000062)
Fatty acid beta-oxidation
(GO:0006635)
Identical protein binding
(GO:0042802)
Inositol trisphosphate biosynthetic process
(GO:0032959)
Intermembrane lipid transfer
(GO:0120009)
Intracellular cholesterol transport
(GO:0032367)
Lipid binding
(GO:0008289)
Lipid hydroperoxide transport
(GO:1901373)
Lipid metabolic process
(GO:0006629)
Lipid transport
(GO:0006869)
Long-chain fatty acyl-coa binding
(GO:0036042)
Mitochondrion
(GO:0005739)
Nucleoplasm
(GO:0005654)
Oleic acid binding
(GO:0070538)
Peroxisomal matrix
(GO:0005782)
Peroxisome
(GO:0005777)
Phosphatidylcholine transfer activity
(GO:0120019)
Phosphatidylethanolamine transfer activity
(GO:1904121)
Phosphatidylinositol transfer activity
(GO:0008526)
Phospholipid transport
(GO:0015914)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of cholesterol biosynthetic process
(GO:0045542)
Positive regulation of cholesterol import
(GO:1904109)
Positive regulation of intracellular cholesterol transport
(GO:0032385)
Positive regulation of steroid biosynthetic process
(GO:0010893)
Positive regulation of steroid metabolic process
(GO:0045940)
Progesterone biosynthetic process
(GO:0006701)
Propanoyl-coa c-acyltransferase activity
(GO:0033814)
Propionyl-coa c2-trimethyltridecanoyltransferase activity
(GO:0050632)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein localization to plasma membrane
(GO:0072659)
Regulation of phospholipid biosynthetic process
(GO:0071071)
Response to estradiol
(GO:0032355)
Response to luteinizing hormone
(GO:0034699)
Signaling receptor binding
(GO:0005102)
Steroid biosynthetic process
(GO:0006694)
Sterol transport
(GO:0015918)

Other Information

Proteins

Non-specific lipid-transfer protein

Genular Protein ID: 462715946

Symbol: SCP2_RAT

Name: Non-specific lipid-transfer protein

UniProtKB Accession Codes:

P11915 Q63383 Q642G0

Database IDs:

Citations:

PubMed ID: 1985920

Title: Cloning, expression, and nucleotide sequence of rat liver sterol carrier protein 2 cDNAs.

PubMed ID: 1985920

DOI: 10.1016/s0021-9258(18)52481-9

PubMed ID: 2034675

Title: Molecular cloning and deduced amino acid sequence of nonspecific lipid transfer protein (sterol carrier protein 2) of rat liver: a higher molecular mass (60 kDa) protein contains the primary sequence of nonspecific lipid transfer protein as its C-terminal part.

PubMed ID: 2034675

DOI: 10.1073/pnas.88.10.4338

PubMed ID: 1915369

Title: Identification of the cDNA clone which encodes the 58-kDa protein containing the amino acid sequence of rat liver non-specific lipid-transfer protein (sterol-carrier protein 2). Homology with rat peroxisomal and mitochondrial 3-oxoacyl-CoA thiolases.

PubMed ID: 1915369

DOI: 10.1111/j.1432-1033.1991.tb16279.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2334427

Title: The amino acid sequence of rat liver non-specific lipid transfer protein (sterol carrier protein 2) is present in a high molecular weight protein: evidence from cDNA analysis.

PubMed ID: 2334427

DOI: 10.1016/0006-291x(90)92367-9

PubMed ID: 2340090

Title: Characterization of a cDNA encoding rat sterol carrier protein2.

PubMed ID: 2340090

DOI: 10.1089/dna.1990.9.159

PubMed ID: 3115977

Title: Primary sequence and structural analysis of sterol carrier protein 2 from rat liver: homology with immunoglobulins.

PubMed ID: 3115977

DOI: 10.1016/s0021-9258(18)45190-3

PubMed ID: 3395344

Title: A mass spectrometric study of the structure of sterol carrier protein SCP2 from rat liver.

PubMed ID: 3395344

DOI: 10.1016/0006-291x(88)90711-5

PubMed ID: 9325339

Title: Substrate specificities of 3-oxoacyl-CoA thiolase A and sterol carrier protein 2/3-oxoacyl-CoA thiolase purified from normal rat liver peroxisomes. Sterol carrier protein 2/3-oxoacyl-CoA thiolase is involved in the metabolism of 2-methyl-branched fatty acids and bile acid intermediates.

PubMed ID: 9325339

DOI: 10.1074/jbc.272.41.26023

PubMed ID: 8063752

Title: Sterol carrier protein X is peroxisomal 3-oxoacyl coenzyme A thiolase with intrinsic sterol carrier and lipid transfer activity.

PubMed ID: 8063752

DOI: 10.1016/s0021-9258(17)31960-9

PubMed ID: 9245689

Title: Sterol carrier protein X (SCPx) is a peroxisomal branched-chain beta-ketothiolase specifically reacting with 3-oxo-pristanoyl-CoA: a new, unique role for SCPx in branched-chain fatty acid metabolism in peroxisomes.

PubMed ID: 9245689

DOI: 10.1006/bbrc.1997.7007

PubMed ID: 9553048

Title: Defective peroxisomal catabolism of branched fatty acyl coenzyme A in mice lacking the sterol carrier protein-2/sterol carrier protein-x gene function.

PubMed ID: 9553048

DOI: 10.1101/gad.12.8.1189

PubMed ID: 10706581

Title: Peroxisomal fatty acid oxidation disorders and 58 kDa sterol carrier protein X (SCPx). Activity measurements in liver and fibroblasts using a newly developed method.

PubMed ID: 10706581

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 547
Mass: 58813
Checksum: D0D1B435D2DC6AFB
Sequence:

MPSVALNSPR LPRVFVVGVG MTKFMKPGGE NSRDYPDLAK EAGQKALADR QIPYSAVEQA 
CVGYVYGEST CGQRAIYHSL GLTGIPIINV NNNCSTGSTA LFMAQQLVQG GLANCVLALG 
FEKMEKGSLG TKYSDRSNPL EKHIDVLINK YGMSACPFAP QLFGSAGKEH METYGTKVEH 
FAKIGWKNHK HSVNNPYSQF QDEYSLDEIM KSRPVFDFLT VLQCCPTSDG AAAAIVSSEE 
FVQKHGLQSK AVEIVAQEMV TDMPSTFEEK SVIKMVGYDM SKEAARKCYE KSGLGPSDVD 
VIELHDCFST NELLTYEALG LCPEGQGGAL VDRGDNTYGG KWVINPSGGL ISKGHPLGAT 
GLAQCAELCW QLRGEAGKRQ VPGAKVALQH NLGLGGAAVV TLYRMGFPEA ASSFRTHQIS 
AAPTSSAGDG FKANLIFKEI EKKLEEEGEE FVKKIGGIFA FKVKDGPGGK EATWVVDVKN 
GKGSVLPDSD KKADCTITMA DSDLLALMTG KMNPQSAFFQ GKLKIAGNMG LAMKLQSLQL 
QPDKAKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Scp2

Associated with

Other Information

Cloning, expression, and nucleotide sequence of rat liver sterol carrier protein 2 cDNAs. PubMed ID: 1985920

Molecular cloning and deduced amino acid sequence of nonspecific lipid transfer protein (sterol carrier protein 2) of rat liver: a higher molecular mass (60 kDa) protein contains the primary sequence of nonspecific lipid transfer protein as its C-terminal part. PubMed ID: 2034675

Identification of the cDNA clone which encodes the 58-kDa protein containing the amino acid sequence of rat liver non-specific lipid-transfer protein (sterol-carrier protein 2). Homology with rat peroxisomal and mitochondrial 3-oxoacyl-CoA thiolases. PubMed ID: 1915369

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The amino acid sequence of rat liver non-specific lipid transfer protein (sterol carrier protein 2) is present in a high molecular weight protein: evidence from cDNA analysis. PubMed ID: 2334427

Characterization of a cDNA encoding rat sterol carrier protein2. PubMed ID: 2340090

Primary sequence and structural analysis of sterol carrier protein 2 from rat liver: homology with immunoglobulins. PubMed ID: 3115977

A mass spectrometric study of the structure of sterol carrier protein SCP2 from rat liver. PubMed ID: 3395344

Sterol carrier protein X is peroxisomal 3-oxoacyl coenzyme A thiolase with intrinsic sterol carrier and lipid transfer activity. PubMed ID: 8063752

Sterol carrier protein X (SCPx) is a peroxisomal branched-chain beta-ketothiolase specifically reacting with 3-oxo-pristanoyl-CoA: a new, unique role for SCPx in branched-chain fatty acid metabolism in peroxisomes. PubMed ID: 9245689

Defective peroxisomal catabolism of branched fatty acyl coenzyme A in mice lacking the sterol carrier protein-2/sterol carrier protein-x gene function. PubMed ID: 9553048

Peroxisomal fatty acid oxidation disorders and 58 kDa sterol carrier protein X (SCPx). Activity measurements in liver and fibroblasts using a newly developed method. PubMed ID: 10706581

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903