Details for: Shox2

Gene ID: 25546

Symbol: Shox2

Ensembl ID: ENSRNOG00000012478

Description: SHOX homeobox 2

Associated with

  • Cardiac atrium morphogenesis
    (GO:0003209)
  • Cardiac pacemaker cell differentiation
    (GO:0060920)
  • Cardiac right atrium morphogenesis
    (GO:0003213)
  • Cartilage development involved in endochondral bone morphogenesis
    (GO:0060351)
  • Chondrocyte development
    (GO:0002063)
  • Chondrocyte differentiation
    (GO:0002062)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Embryonic digestive tract morphogenesis
    (GO:0048557)
  • Embryonic forelimb morphogenesis
    (GO:0035115)
  • Embryonic limb morphogenesis
    (GO:0030326)
  • Embryonic morphogenesis
    (GO:0048598)
  • Embryonic skeletal joint morphogenesis
    (GO:0060272)
  • Heart valve development
    (GO:0003170)
  • Mesenchymal cell proliferation
    (GO:0010463)
  • Muscle tissue morphogenesis
    (GO:0060415)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Osteoblast differentiation
    (GO:0001649)
  • Positive regulation of axonogenesis
    (GO:0050772)
  • Positive regulation of mesenchymal cell proliferation
    (GO:0002053)
  • Positive regulation of skeletal muscle fiber development
    (GO:0048743)
  • Positive regulation of smoothened signaling pathway
    (GO:0045880)
  • Positive regulation of stem cell proliferation
    (GO:2000648)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of branching morphogenesis of a nerve
    (GO:2000172)
  • Regulation of chondrocyte differentiation
    (GO:0032330)
  • Regulation of heart rate
    (GO:0002027)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Sinoatrial node cell development
    (GO:0060931)
  • Sinoatrial node development
    (GO:0003163)
  • Sinoatrial valve development
    (GO:0003172)
  • Smoothened signaling pathway
    (GO:0007224)
  • Stem cell proliferation
    (GO:0072089)

Other Information

Genular Protein ID: 4278069801

Symbol: SHOX2_RAT

Name: Short stature homeobox protein 2

UniProtKB Accession Codes:

O35750 O35749 O35751

Database IDs:

AGR 1 AlphaFoldDB 1 CDD 1 CTD 1 EMBL 3 GO 35 Gene3D 1 InParanoid 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 eggNOG 1 jPOST 1

Citations:

PubMed ID: 9371788

Title: Homeobox gene Prx3 expression in rodent brain and extraneural tissues.

PubMed ID: 9371788

DOI: 10.1073/pnas.94.24.12993

Sequence Information:

  • Length: 237
  • Mass: 26221
  • Checksum: 96702BF3A25A144A
  • Sequence:
    • RELDMGAAER SREPGSPRLT EVSPELKDRK EDAKGMEDEG QTKIKQRRSR TNFTLEQLNE 
LERLFDETHY PDAFMREELS QRLGLSEARV QVWFQNRRAK CRKQENQLHK GVLIGAASQF 
EACRVAPYVN VGALRMPFQQ DSHCNVTPLS FQVQAHVQLD SAVRAAHHHL HPHLAAHGPY 
MMFPAPPFGL PLATLAADSA SAASVVAAAA AAKTTSKNSS IADLRLKAKK HAAALGL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.