Slc1a1 | ENSRNOG00000014816 | NCBI 25550

Details for: Slc1a1

Gene ID: 25550

Symbol: Slc1a1

Ensembl ID: ENSRNOG00000014816

Description: solute carrier family 1 member 1

Associated with

Glutamate neurotransmitter release cycle
(R-RNO-210500)
Neuronal system
(R-RNO-112316)
Neurotransmitter release cycle
(R-RNO-112310)
Slc-mediated transmembrane transport
(R-RNO-425407)
Transmission across chemical synapses
(R-RNO-112315)
Transport of inorganic cations/anions and amino acids/oligopeptides
(R-RNO-425393)
Transport of small molecules
(R-RNO-382551)
Acidic amino acid transmembrane transporter activity
(GO:0015172)
Adult behavior
(GO:0030534)
Apical plasma membrane
(GO:0016324)
Axon
(GO:0030424)
Behavioral fear response
(GO:0001662)
Blood vessel morphogenesis
(GO:0048514)
Brain development
(GO:0007420)
Cell surface
(GO:0009986)
Cellular response to ammonium ion
(GO:0071242)
Cellular response to bisphenol a
(GO:1903926)
Cellular response to cocaine
(GO:0071314)
Cellular response to mercury ion
(GO:0071288)
Cellular response to organic cyclic compound
(GO:0071407)
Cellular response to oxidative stress
(GO:0034599)
Chloride transmembrane transport
(GO:1902476)
Chloride transmembrane transporter activity
(GO:0015108)
Conditioned place preference
(GO:1990708)
Cysteine transmembrane transport
(GO:1903712)
Cysteine transmembrane transporter activity
(GO:0033229)
Cysteine transport
(GO:0042883)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytoplasm
(GO:0005737)
D-aspartate import across plasma membrane
(GO:0070779)
D-aspartate transmembrane transporter activity
(GO:0140010)
D-aspartate transport
(GO:0070777)
Dendrite
(GO:0030425)
Dopamine metabolic process
(GO:0042417)
Dopamine receptor signaling pathway
(GO:0007212)
Early endosome membrane
(GO:0031901)
Endoplasmic reticulum
(GO:0005783)
Establishment of protein localization
(GO:0045184)
Gene expression
(GO:0010467)
Glutamate:sodium symporter activity
(GO:0015501)
Glutamate binding
(GO:0016595)
Glutamate receptor signaling pathway
(GO:0007215)
Glutathione biosynthetic process
(GO:0006750)
Glutathione metabolic process
(GO:0006749)
Grooming behavior
(GO:0007625)
Heart contraction
(GO:0060047)
High-affinity l-glutamate transmembrane transporter activity
(GO:0005314)
Identical protein binding
(GO:0042802)
Intracellular glutamate homeostasis
(GO:0090461)
Intracellular zinc ion homeostasis
(GO:0006882)
L-amino acid transmembrane transporter activity
(GO:0015179)
L-aspartate import across plasma membrane
(GO:0140009)
L-aspartate transmembrane transport
(GO:0070778)
L-aspartate transmembrane transporter activity
(GO:0015183)
L-glutamate import
(GO:0051938)
L-glutamate import across plasma membrane
(GO:0098712)
L-glutamate transmembrane transport
(GO:0015813)
L-glutamate transmembrane transporter activity
(GO:0005313)
Late endosome membrane
(GO:0031902)
Learning or memory
(GO:0007611)
Locomotory behavior
(GO:0007626)
Long-term synaptic potentiation
(GO:0060291)
Maintenance of blood-brain barrier
(GO:0035633)
Membrane
(GO:0016020)
Memory
(GO:0007613)
Metal ion binding
(GO:0046872)
Monoatomic anion channel activity
(GO:0005253)
Motor behavior
(GO:0061744)
Motor neuron apoptotic process
(GO:0097049)
Negative regulation of neuron apoptotic process
(GO:0043524)
Neurogenesis
(GO:0022008)
Neuron apoptotic process
(GO:0051402)
Neurotransmitter receptor transport to plasma membrane
(GO:0098877)
Plasma membrane
(GO:0005886)
Positive regulation of heart rate
(GO:0010460)
Postsynaptic modulation of chemical synaptic transmission
(GO:0099170)
Protein binding
(GO:0005515)
Regulation of heart rate
(GO:0002027)
Regulation of protein phosphorylation
(GO:0001932)
Regulation of protein targeting to membrane
(GO:0090313)
Response to amphetamine
(GO:0001975)
Response to anesthetic
(GO:0072347)
Response to axon injury
(GO:0048678)
Response to decreased oxygen levels
(GO:0036293)
Response to morphine
(GO:0043278)
Response to xenobiotic stimulus
(GO:0009410)
Retina development in camera-type eye
(GO:0060041)
Retina layer formation
(GO:0010842)
Righting reflex
(GO:0060013)
Superoxide metabolic process
(GO:0006801)
Symporter activity
(GO:0015293)
Synapse organization
(GO:0050808)
Zinc ion transmembrane transport
(GO:0071577)

Other Information

Proteins

Excitatory amino acid transporter 3

Genular Protein ID: 3976159489

Symbol: EAA3_RAT

Name: Excitatory amino acid transporter 3

UniProtKB Accession Codes:

P51907 O88389 Q63727 Q9JJP8

Database IDs:

Citations:

PubMed ID: 9011753

Title: Cloning and expression of a neuronal rat brain glutamate transporter.

PubMed ID: 9011753

DOI: 10.1016/0169-328x(95)00279-2

PubMed ID: 8747153

Title: Neuronal high-affinity glutamate transport in the rat central nervous system.

PubMed ID: 8747153

DOI: 10.1097/00001756-199511270-00020

PubMed ID: 8613726

Title: Nerve injury enhances rat neuronal glutamate transporter expression: identification by differential display PCR.

PubMed ID: 8613726

DOI: 10.1523/jneurosci.15-12-07872.1995

PubMed ID: 8772431

Title: Characterization and distribution of the neuronal glutamate transporter EAAC1 in rat brain.

PubMed ID: 8772431

DOI: 10.1152/ajpcell.1996.270.1.c67

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8738164

Title: Rat C6 and human astrocytic tumor cells express a neuronal type of glutamate transporter.

PubMed ID: 8738164

DOI: 10.1016/0169-328x(95)00331-l

PubMed ID: 11242046

Title: Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18.

PubMed ID: 11242046

DOI: 10.1038/35065084

PubMed ID: 19720795

Title: Functional role of neuroendocrine-specific protein-like 1 in membrane translocation of GLUT4.

PubMed ID: 19720795

DOI: 10.2337/db09-0756

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 523
Mass: 56772
Checksum: D6783244E37640E4
Sequence:

MGKPTSSGCD WRRFLRNHWL LLSTVAAVVL GIVVGVLVRG HSELSNLDKF YFAFPGEILM 
RMLKLVILPL IISSMITGVA ALDSNVSGKI GLRAVVYYFS TTVIAVILGI VLVVSIKPGV 
TQKVNEINRT GKTPEVSTVD AMLDLIRNMF PENLVQACFQ QYKTKREEVK PASDPGGNQT 
EVSVTTAMTT MSENKTKEYK IVGLYSDGIN VLGLIIFCLV FGLVIGKMGE KGQILVDFFN 
ALSDATMKIV QIIMCYMPIG ILFLIAGKII EVEDWEIFRK LGLYMATVLS GLAIHSLVVL 
PLIYFIVVRK NPFRFALGMA QALLTALMIS SSSATLPVTF RCAEEKNHVD KRITRFVLPV 
GATINMDGTA LYEAVAAVFI AQLNGMDLSI GQIITISITA TAASIGAAGV PQAGLVTMVI 
VLSAVGLPAE DVTLIIAVDW LLDRFRTMVN VLGDAFGTGI VEKLSKKELE QVDVSSEVNI 
VNPFALEPTI LDNEDSDTKK SYVNGGFSVD KSDTISFTQT SQF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Slc1a1

Associated with

Other Information

Cloning and expression of a neuronal rat brain glutamate transporter. PubMed ID: 9011753

Neuronal high-affinity glutamate transport in the rat central nervous system. PubMed ID: 8747153

Nerve injury enhances rat neuronal glutamate transporter expression: identification by differential display PCR. PubMed ID: 8613726

Characterization and distribution of the neuronal glutamate transporter EAAC1 in rat brain. PubMed ID: 8772431

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Rat C6 and human astrocytic tumor cells express a neuronal type of glutamate transporter. PubMed ID: 8738164

Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18. PubMed ID: 11242046

Functional role of neuroendocrine-specific protein-like 1 in membrane translocation of GLUT4. PubMed ID: 19720795

Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. PubMed ID: 22673903